Evaluation of Antihyperglycemic Activity of a Polyherbal Formulation in Alloxan induced Diabetic Rats
ABOUT AUTHORS:
S Hamza*, Dr D. K. Suresh, R. Hasan, Md S. Khalid, R. Mistry
Department of Pharmacology,
Luqman College of Pharmacy,
Gulbarga - 585 102,
Karnataka, India.
ABSTRACT:
The study was to assess the antidiabetic activity ofa polyherbal formulation in alloxan induced diabetic rats. The antidiabetic activity of a polyherbal formulation in alloxan induced diabetic rats was assessed using Alloxan β-cytotoxin induced chemical diabetes in a wide variety of wistar albinorats. The polyherbal formulation contains thefollowing plants leaves of Gymnema sylvestre, Ginkgo biloba and plant seeds of Mucuna prurience.The extracts were prepared by continues hot soxhlet extraction using petroleum ether and water. Three different formulations were prepared for the study. The study reveals that the polyherbal formulations of plants leaves of Gymnema sylvestre, Ginkgo biloba and plant seeds of Mucuna prurience have antidiabetic activity and theactionmay be due to the restoration or regeneration of β-cells of pancreas.
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About Authors:
National Institute of Pharmaceutical Education and Research (NIPER) under the aegis of Ministry of Chemicals and Fertilizers (Department of Pharmaceuticals), Govt, of India, is an institute of National Importance created by an Act of Parliament devoted to the promotion of pharmaceutical education and research. The Institute is located at SAS Nagar, adjoining the beautiful city of Chandigarh.
