ANSWERS of Previous PharmaQUIZ-29:

1.B    2.B    3.C    4.C    5.C

6.D    7.B    8.D    9.A    10.B

Aarkay Food Products Ltd came into existence in the year 1982 when India based “Kapoor Family” established a Manufacturing Facility dedicated solely to develop Natural Ingredients and Additives for the Food and Beverage Industry.

Sun Pharma make speciality pharmaceuticals and active pharmaceutical ingredients. Sun Pharma's brands are prescribed in chronic therapy areas like cardiology, psychiatry, neurology, gastroenterology, diabetology and respiratory.

ZANEKA HEALTH CARE PVT LTD. is manufacturing more than 400 formulations in the form of tablets, capsules, Dry syrup (Beta Lactum & Non Beta lactum), Ointments, Liquid Syrup & Dry Powder Injections (Beta Lactum)
They at ZANEKA believe that if their customer is happy then they are happy. They are committed to deliver high standard of product and develop products with the feedbacks from the customer and the final consumer following the proper WHO GMP guidelines.

At the Federation's 71st International Congress in Hyderabad, India, the World Health Organization (WHO) and the International Pharmaceutical Federation (FIP) signed a Joint Statement on the role of pharmacists in tuberculosis care and control

About Authors:
Nishant Gupta
Department of pharmaceutics,
B.N. College of pharmacy,
Udaipur-313002,
Rajasthan

ABSTRACT:
Paroxetine (PRX) crystals exhibit poor compressibility, poor flowability and its tablets show a tendency to cap. To improve the mechanical strength of tablets several kinds of “Paroxetine for direct compression” are present on the market. Current research demonstrated the best tablet properties with coated paroxetine (mass of tablets, diameter, height and mechanical strength, friability RSD<2%). Furthermore, coated paroxetine in combination with both investigated superdisintegrants such as Vivasol® and Polyplasdone® XL-10 shows faster disintegration time and dissolution rate in comparison to paroxetine for direct compression. Eventually, the major advantages of the formulation with coated paroxetine for industrial production are decrease of friability and superiority in terms of flowability, compressibility, quick disintegration and dissolution. Regarding the results, coating of PRX particles is beneficial for the manufacturing of tablets with immediate release.

About Authors:
Nishant Gupta
Department of pharmaceutics,
B.N. College of pharmacy,
Udaipur-313002,
Rajasthan

ABSTRACT:
Cancer is the leading cause of death in the United States among people younger than 85 years, and for the first time has surpassed heart disease as the number one killer. This worrisome statistic has resulted not from an increase in the incidence of cancer, but because deaths from heart disease have dropped nearly in half while the number of cancer-related deaths has remained about the same. This fact accentuates the need for a new generation of more effective therapies for cancer. Cancer patients are typically exposed to chemotherapy and radiation therapy in separate treatment rounds, doubling their emotional and physical stress. Biopharmaceutical researchers are now working on 887 medicines for cancer, according to a new report by the Pharmaceutical Research and Manufacturers of America (PhRMA). Many are high-tech weapons to fight the disease, while some involve innovative research into using existing medicines in new ways. Few things cause patients more fear and apprehension than a cancer diagnosis. But today—because of early detection and a steady stream of new and improved treatments—cancer increasingly can be managed and even beaten.

Indian Institute of Science Education and Research Bhopal was created in 2008 by the Ministry of Human Resource Development, Government of India. Its mission is to provide quality science education to UG and PG students. The prime focus is to integrate science education and research with a motive of attracting bright students and world class faculty.

Mylan is one of the world’s leading generics and specialty pharmaceutical companies, providing products to customers in more than 150 countries and territories. The company maintains one of the industry’s broadest and highest quality product portfolios, which is regularly bolstered by an innovative and robust product pipeline.

SAVA Medica Limited is a leading pharmaceutical company based in India. Human life is precious to us. That is why we, at SAVA Medica, are committed to provide such products which can improve human health & life at affordable cost.

Wallace Pharmaceuticals is a progressive, professionally managed and growing pharmaceutical company with a special focus on Antibiotic, Anti -infective, Analgesic, Anti-inflammatory, Antiacne, Paediatric, Orthopaedic, Dermatology and Diabetic segments.

Post: Product Manager

NEXTUS SOLUTIONS is a professionally managed organization engaged in offering highly acclaimed consulting, Training and Placement. With our in- depth expertise and rich experience in the field of domestic as well as international level, we have been serving aspiring candidatesand organizations in the most professional way.

About Authors:
DHAVAL PATEL ^*[1], Dr. PANKAJ SHAH ^[2]
1 School of Pharmaceutical Sciences,
Jaipur National University, Jaipur -302025, (Rajasthan.), India
² institute of kidney disease and research center,
Civil hospital, Ahmedabad (Gujarat), India

Abstract:
Inpresent study, comorbidities and laboratory abnormalities of telbivudine was analysed in hepatitis b patients. Clinical data were collected from hepatitis b patients that presented with laboratory abnormalities to telbivudine. We examined 100 patients of hepatitis b  who treated with telbivudine in i.k.d.r.c, civil hospital, Ahmedabad from January 2009 to February 2011, out of these twenty patients had used other nucleoside analogue in past. The main laboratory abnormalities were elevation of creatine kinase, elevation of ALT and elevation of AST. Hypertension was the major comorbidities with the hepatitis b.The laboratory abnormalities were related to telbivudine, but the biological mechanism of the reaction is not clear.

About Author: Rinki Verma (Research fellow)
Center of Experimental Medicine and Surgery,
Institute of Medical science
Banaras Hindu University
Varanasi - 221005

Abstract:
In 1965 ,  firstly fragility was reported in cells of  a femeal previously irradiated and described  as non-random human chromosome called “ Fragile sites”  are heritable specific chromosome loci that exhibit an increased frequency of gaps, poor staining, constrictions or breaks when chromosomes are exposed to partial DNA replication inhibition. They constitute areas of chromatin that fail to compact during mitosis. They are classified as rare or common depending on their frequency within the population and are further subdivided on the basis of their specific induction chemistry into different groups differentiated as folate sensitive or non-folate sensitive rare fragile sites, and as aphidicolin, bromodeoxyuridine (BrdU) or 5-azacytidine inducible common fragile sites. Most of the known inducers of fragility share in common their potentiality to inhibit the elongation of DNA replication, particularly at fragile site loci. There are seven non-similar folate sensitive (FRA10A, FRA11B, FRA12A, FRA16A, FRAXA, FRAXE and FRAXF) and two non-folate sensitive (FRA10B and FRA16B) and  have been molecularly characterized. Due to dynamic mutation formed DNA repeat sequences and  involving the normally occurring polymorphic CCG/CGG trinucleotide repeats at the folate sensitive and AT-rich minisatellite repeats at the non-folate sensitive fragile sites. These rare fragile site FRAXA is the most important fragile site as it is associated with the fragile X syndrome significant to the clinical side and also explained the predisposition of tumors.

Piramal Healthcare Limited A major force in the pharmaceuticals and healthcare segment, Piramal Healthcare Limited, incorporating Healthcare Solutions & Pharma Solutions, has an unequivocal vision – to become the most admired pharmaceutical company, with leadership in market share and profits.

Sigma Institute of Technology and Engineering trust is a registered charitable trust, having registration Number E/6432, and dated 8/1/2004, under public trust Act. The trust registered at Vadodara, has a mission to impart quality education that empowers generation next to build better environment for all. We at the trust follow the footsteps of Sir Sayajirao Gaikwad  in furthering this vision that education reaches all and helps build better tomorrow for all.

ANSWERS of Previous PharmaQUIZ-28:

1.A    2.C    3.A    4.C    5.B

6.B    7.D    8.D    9.A    10.A

Biocon is a research-driven, global healthcare company with a strong matrix of capabilities along the biopharmaceutical value chain. Focusing on unmet medical needs in cancer, diabetes and inflammatory diseases, it offers novel therapies on a platform of affordable innovation.
Biocon together with group companies employs more than 2500 employees with approxmimately Rs 1,000 crore turnover and is expected to grow further during the current financial year.

IIT Bombay, set up by an Act of Parliament, was established in 1958, at Powai, a northern suburb of Mumbai. Today the Institute is recognised as one of the centres of academic excellence in the country. Over the years, there has been dynamic progress at IIT Bombay in all academic and research activities, and a parallel improvement in facilities and infrastructure, to keep it on par with the best institutions in the world. Institutes in positions of excellence grow with time.