UNDERSTAND DESIGN, SETUP, AND EXECUTION OF IN VIVO PHARMACOLOGY MODELS FOR EXPERIMENTS ASSOCIATED WITH GROSS IMMUNOLOGY, SOLID TUMORS, AND HEME-ONCOLOGY
Candidate should have knowledge of theoretical working principle of KF auto titrator, dissolution, spectroscopic instruments e.g. UV spectrometer, IR and Chromatographic instruments e.g. HPLC, GC
Syngene is an innovation-led contract research, development and manufacturing organization offering integrated scientific services from early discovery to commercial supply.
Personnel handling this profile will be responsible for performing reactions as per the requirement of the project. They are also responsible for documenting the observations in relevant note books.
To participate in sample processing for PK, ADME assays and handling of LCMS/MS. Ability to adapt to the dynamic team environment. Processing of different matrices samples of PK studies. Optimization of test compounds manually as well as automated on LCMS/MS. M.Pharm in Pharmaceutical sciences, Pharmaceutical Analysis who has interest and passion for LC/MS related bioanalysis
The candidate must possess a thorough understanding of relevant disease biology, the clinical landscape, emerging technologies, and the competitive environment.
Ability to interpret and troubleshoot data generated. Knowledge on working with small molecules and membrane proteins in a Biacore instrument will be an added advantage.
The ideal candidate will ensure smooth running of multiple cell-based and biochemical assays while maintaining highest quality and integrity of data and meeting established timelines.
The candidate must possess experience in animal handling, conducting studies, sample handling, PK data analysis and interpretation of results. Jugular vein cannulation and any other surgical skill will be desirable.