Pharmapedia

  • All things are poison; It is only the dose that makes a medicine not a poison
    3 May 2025

    All things are poison; It is only the dose that makes a medicine not a poison

    The very famous quote credited to Paracelsus who expressed the classic toxicology maxim that, "All things are poison, and nothing is without poison; only the dose makes a thing not a poison." The principle relies on the finding that all chemicals, even water and oxygen can be toxic if too much is eaten, drunk, or absorbed. The idea simply describes the phenomenon in which poisonous substances can be medicinal in small doses.

  • 17 April 2025
    Supercharged mitochondria spark aging-related blood disorders

    As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give the cells a growth advantage, laying the foundation for developing serious health conditions. Now, scientists at The Jackson Laboratory (JAX) have not only discovered the mechanism that fuels their unchecked growth but have also found a way to stop it.

  • 31 March 2025
    Google launches TxGemma, entering in Healthcare

    Google is excited to release TxGemma, a collection of open models designed to improve the efficiency of therapeutic development by leveraging the power of large language models. Developing a new therapeutic is risky, notoriously slow, and can cost billions of dollars. 90% of drug candidates fail beyond phase 1 trials.

  • 27 March 2025
    Surprising New Role for Lungs : Making Blood

    Using video microscopy in the living mouse lung, UC San Francisco scientists have revealed that the lungs play a previously unrecognized role in blood production. As reported online March 22, 2017, in Nature, the researchers found that the lungs produced more than half of the platelets – blood components required for the clotting that stanches bleeding – in the mouse circulation.

  • 11 March 2025
    Cryo-Electron Microscopy reveals hidden mechanics of DNA Replication, sheds new light on cancer target

    Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library your genome, which totals more than 3 billion base pairs of DNA has to be copied, precisely, from the parent cell to the new daughter cell.

  • 7 March 2025
    Exosomes in Cosmetics

    Vinay KumarVinay Kumar Singh. 
    Head-Formulation
    Kumar Organic Products Research Centre Pvt. Ltd.,
    Bengaluru
    Email : formulation_krc@kopresearchcentre.net

  • 20 February 2025
    Dysfunctional B Cells is a new Cancer Immunotherapy Target
    University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood, known as the tertiary lymphoid structure, where they become frustratingly dysfunctional when in close contact with tumors.
  • 10 January 2025
    Koprosteine (Procysteine) : Multifunctional active

    Vinay KumarVinay Kumar Singh. 
    Head-Formulation
    Kumar Organic Products Research Centre Pvt. Ltd.,
    Bengaluru
    Email : formulation_krc@kopresearchcentre.net

  • 13 December 2024
    Antidepressants may act in gut to reduce depression and anxiety

    Most of us have experienced the effects of moods and emotions on our gastrointestinal tract, from “butterflies” in the stomach caused by nervousness to a loss of appetite when we’re feeling blue.

  • 12 December 2024
    Stanford scientists transform ubiquitous skin bacterium into a topical vaccine

    Imagine a world in which a vaccine is a cream you rub onto your skin instead of a needle a health care worker pushes into your one of your muscles. Even better, it’s entirely pain-free and not followed by fever, swelling, redness or a sore arm. No standing in a long line to get it. Plus, it’s cheap.

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