Telangana

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ABOUT AUTHORS
Goundla Uday Bhasker Goud¹*, Jakkampudi Sri Venu Prakash¹, Avadhanam Pranav Kumar², Gangi Reddy Sreenivas Reddy², Manikanta Sai Krishna².
¹Department of Industrial Pharmacy
²Department of Pharmaceutics
Bharat Institute Of Technology, Mangalpally, Hyd, Telangana, India.
gouds.uday04@gmail.com

ABSTRACT
Aim: The current paper was an attempt to design a extended release dosage form of Metformin hydrochloride using various grades of hydrophilic polymers, hydroxy propyl methyl cellulose (HPMC K4M, HPMC K15M, HPMC K100M and HPMC K200M) and MCC.
Materials and Methods: Laboratory scale batches of 4 tablet formulations were prepared by wet granulation technique. Precompression parameters of the granules were evaluated prior to compression. Tablets were characterized as crushing strength, friability, weight variation, thickness, drug content or assay and evaluated for in-vitro release pattern for 12 hr using Phosphate buffer of pH 6.8 at 37 ± 0.5°C.
Results and Discussion: The results obtained revealed that HPMC K100M in formulation (F3) was able to sustain the drug release for 12 h and followed the Higuchi pattern quasi-Fickian diffusion. and charged for stability testing, parameters were within the limit of acceptance. There was no chemical interaction found between the drug and excipients during Fourier Transform Infrared Spectroscopy (FTIR).
Conclusion: Hence it can be concluded that formulation F3 containing HPMC K100M is suitable for development of extended release tablets of Metformin Hydrochloride.

Post: Assistant Drugs Controller(India)

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No.of post: 10, UR-04, OBC-01, SC-04, ST-01

Eligible candidates are invited to attend WALK - IN - INTERVIEW on the following date at 9.30 a.m. sharp for the following positions on the ad hoc research project entitled “Vitamin A metabolic pathway on region – specific adipose tissue development and its relevance to insulin resistance: A proteomic approach to sexual dimorphism”. The essential qualification, experience, consolidated Fellowship and service tenure are as under: The project is funded by DBT.

Post: Junior Research Fellow- 02 nos.

The University of Hyderabad (UoH), one of the major institutions of higher education in India is largely devoted to postgraduate studies and is widely known for its excellence in research and for its distinguished faculty. Founded in 1974 with Prof. Gurbaksh Singh as its first Vice Chancellor, UoH - also known as Hyderabad Central University or HCU- has emerged as a leading centre of teaching and research. The large campus located near Gachibowli, which is the IT hub of Hyderabad, has immense bio-diversity and is home to over 75 varieties of bird, not to speak of the lakes and rock formations which give the campus a natural beauty.

Applications are invited from the eligible candidates (Indian Nationals only) on a plain paper for the following temporary posts in the research projects sponsored by DBT, New Delhi.

Post: Technical Assistant, Project Assistant

Nalanda College of Pharmacy (NCOP) was established in the year 1995 and is currently running different courses in Pharmacy ranging from Diploma to Post Graduation. NCOP is known for providing quality education in Pharmacy and recognized as the best college in the region.In the field of research, NCOP has created history in undertaking various useful research projects and published record number of research papers in the renowned journals around the globel. NCOP has also secured AICTE-MODROB and AICTE-RPS schemes for 2013-14 academic session.

Post: Professors / Associate Professor / Assistant Professor / Lecturers

About Authors:
*M.C.Sai HariKishan, C.P.Meher, S.M.Ahmed
Maheshwara Institute Of Pharmacy, Chitkul, Isnapur ,
Patancheru, Hyderabad-502307
*hari_mc@yahoo.com