Banaras Hindu University

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  • 10 January 2013

    Banaras Hindu University invites Junior Research Fellow, Senior Research Fellow, Research Associate

    Banaras Hindu University ranks among the first few in the country in the field of academic and research output. This university has two campuses, 3 institutes, 16 faculties, 140 departments, 4 advanced centers and 4 interdisciplinary schools.

  • 21 December 2012
    ANTIANXIETY ACTIVITY OF EMBELIN ISOLATED FROM EMBELIA RIBES

    About Authors:
    Mukesh Bansal1*, Indrajeet Singhvi2, Santosh Gupta2
    1Department of Pharmaceutics, Indian Institute of Technology (Banaras Hindu University), Varanasi, U.P., India.
    2Pacific College of Pharmacy, Pacific University, Udaipur, Rajasthan, India.
    *bansalpharma1987@gmail.com

    Abstract:
    Object:
    To investigate the effect of embelin  on anxiety   was studied  by using standard test such as Elevated zero-maze test and Novelty induced suppressed feeding latency test in a dose dependent manner.
    Material & methods:
    This portion include extraction and isolation of embelin, animals were obtained from the animal house IMS, BHU, Varanasi, India, and methods for anxiety were Elevated zero-maze test and Novelty induced suppressed feeding latency test.
    Result & conclusion:
    The  anxiolytic  activity was found at 20mg/kg. The observed anxiolytic effect of this compound seems to be regulated through monoaminergic system in the brain and the activity was comparable to diazepam.

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