Drug Inspector

1. Assume that for digoxin, the therapeutic range is cited as Cavg 5.5 = 0.8 - 2 mg/ml. If the patient is assumed to have an estimated digoxin t1/2 of 48 hours, how long would you wait to take serum digoxin concentration measurement and when during the dosing interval would you schedule it? 
(a) 28 days then 3-4 hours after the dose is administered 
(b) 14 days then 6-8 hours after the dose is administered 
(c) 7 days then 10-14 hours after the dose is administered 
(d) 3 days then 1-2 hours after the dose is administered 

1. Separation of a tablet into two or more distinct layers is called as
(a) Capping
(b) Mottling
(c) Chipping
(d) Lamination
Correct Answer : (a) Capping

2. The polyethylene glycol ointment is an example of which type of ointment base?
(a) Hydrocarbon base
(b) Absorption base
(c) Cream base
(d) Water-soluble base
Correct Answer : (a) Hydrocarbon base

3. In the production facility of injectable drug products, the water for injection is stored in tanks at
(a) 10°C
(b) 37°C
(c) 50°C
(d) 80°C Correct Answer : (b) 37°C

1. A non-volatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection, it produces general anaesthesia for 10 minutes. Which process is responsible for termination of its action?
(a) Metabolism in liver
(b) Excretion by kidney
(c) Plasma Protein Binding
(d) Redistribution

2. Aspirin overdose is characterized by:
(a) Hyperthermia, metabolic acidosis and coma
(b) Fever, hepatic dysfunction and encephalopathy
(c) Rash, interstitial nephritis and acute renal failure
(d) Rapid, fulminant hepatic failure

Applications are invited from eligible candidates for appointment to the 43 posts of Drugs lnspector (Medical Devices) Gazetted, Non-ministerial, Pay level 8 (Rs.47600-151 100) of 7th CPC in the Central Drugs Standard Control Organisation, Directorate General of Health Services, Ministry of Health & Family Welfare on deputation basis across all the zones/ sub-zones including Head Quarter under the CDSCO.

Post : Drugs Inspector

No of posts : 43