Orissa

Regional Plant Resource Centre was established in 1985 as a recreational garden and with an aim to provide a green lung for the inhabitants of Bhubaneswar – the capital city of Orissa. Gradually it became a dynamic and vibrant research organization of the State Government with a focus on the conservation of plant biodiversity.

Applications are invited from eligible computer literate candidates for filling up of the posts as mentioned below under National Rural Health Mission, Odisha on contractual basis and subject to renewal as per the society norms. Performance Incentives and Annual increment is admissible as per the norms of the society besides the remuneration noted against each post. Upper age limit for applicants with MBBS background 68 years and for others 65 years as on 05.01.2013.

About Authors:
V. KRISHNA KISHORE
M.Pharm, 2nd Sem (Pharmaceutics)
Roland Institute of  Pharmaceutical Sciences , Berhampur, Odisha.
Krishnakishorev58@gmail.com

1. Abstract:
Pharmacokinetics is currently defined as the study of the time course of drug absorption, distribution, metabolism, and excretion. Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient.
Primary goals of clinical pharmacokinetics include enhancing efficacy and decreasing toxicity of a patient's drug therapy. The development of strong correlations between drug concentrations and their pharmacologic responses has enabled clinicians to apply pharmacokinetic principles to actual patient situations.
A drug's effect is often related to its concentration at the site of action, so it would be useful to monitor this concentration. Receptor sites of drugs are generally inaccessible to our observations or are widely distributed in the body, and therefore direct measurement of drug concentrations at these sites is not practical. For example, the receptor sites for digoxin are believed to be within the myocardium, and we cannot directly sample drug concentration in this tissue. However, we can measure drug concentration in the blood or plasma, urine, saliva, and other easily sampled fluids.

Since inception, Siksha 'O’ Anusandban Deemed University has been imparting quality education to its students through various constituent institutes with an objective to promote professional education, training, research & development in diverse fields.

National Institute of Technology, Rourkela (NIT) formerly known as Regional Engineering College, (REC) is one of the premier national level institutions for technical education in the country. and is funded by the Government of India. Government of India has elevated the Regional Engineering College, Rourkela to a deemed university under the name of National Institute of Technology, Rourkela.

About Authors:
Mortoza Rahaman
B.Pharm, BCDA College of Pharmacy & Technology (WBUT), WB
M.Pharm, Dadhichi College of Pharmacy, (BPUT), Orissa
mortozarahaman970@gmail.com

Abstract:
Novel drug delivery systems have several advantages over conventional multi dose therapy. Recent trends indicate that microparticulate drug delivery systems are especially suitable for achieving controlled or delayed release oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns as well as reproducible and short gastric residence time. The release of drug from microparticles depends on a variety of factors including the carrier used to form the microparticles and the amount of drug contained in them. Consequently, microparticulate drug delivery systems provide tremendous opportunities for designing new controlled and delayed release oral formulations, thus extending the frontier of future pharmaceutical development. One such approach is using microspheres as carriers for drugs. Microencapsulation is a process where by small discrete solid particles or small liquid droplets are surrounded and enclosed by an intact shell. Microencapsulation is used to modify and delayed drug release form pharmaceutical dosage forms. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a particular drug. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. The intent of the paper is to highlight the potential of microencapsulation technique as a vital technique in novel drug delivery.

Walk-in-Interview for filling of the following catagories of the Contractual Post under ZSS of Dhenkanal District.

Post: MPHW(M)

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Post: Pharmacist on Contractual basis

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No of Vacancy as per ORV act: No of Vacancy-:4 (ST-4)