Miscellaneous Articles

SOY-BASED DIET: A MESMERIZING TRIUMPH FOR WELLNESS

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There are three topics that can cause derision and division at any coffee or dinner table across the Western world: religion, politics, and soy. The humble soybean does have a noble and ingrained place in our world today and, whether you are pro or no, it’s almost unavoidable. Soy is everywhere - from your soy milks and tofus to the more discreet soy lecithin used to prevent compounds from separating during the cooking process. 

CHALLENGING ROLE OF PHARMACIST IN HEALTH CARE THE FUTURE PROSPECTS

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MODERN PHARMACIST:
One who is able to provide the patient oriented services as in developed countries is called as a modern pharmacist. Such services start from obtaining patients medication history to the feedback from the same after discharge. The componential characteristics that a modern hospital pharmacist must possess include:
1. Professional knowledge
2. Computer / IT acquaintance & skill
3. Counseling and communication skills

MEDICINAL VALUE OF CAROM SEEDS – AN OVERVIEW

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The carom seeds botanical name Trachy spermumammi belong to the family of Apiaceae (Umbelliferae), of the genus; Trachyspermum. The Umbellifers are the members of carrot or parsley family, which includes many herbs and spices such as dill, fennel, anise seed, and caraway, is an annual herbal plant growing up to 3 feet in height.  Some of the common names for the seeds are Bishop’s Weed, Ajowan, carom, Caraway and thymol seeds.etc. Carom seeds are ovoid, light brown colour seeds. They have narrow green leaves and small delicate flowers. The fruits pods of these plants are often called seeds for their seed-like appearance. The Carom plants are believed to have originated from Egypt in Middle East. They are widely grown in India, Afghanistan and Iran. These plants can be grown easily from the seeds.Well drained loam soil with a pH between 6.5 and 8.2 is ideal for their cultivation. They grow well in cold temperatures ranging from 15 °C to 25 °C. The plants can grow both in direct and partial sunlight. Relative humidity between 65% and 70 % are required for their proper growth. The umbels are harvested after they are properly matured. Harvesting is done during the later parts of winter or earlier in spring. These seeds are used as a spice in cooking. The umbels of the plant mature and produce the seeds. Ajwain is renowned for their medicinal value. Ajwain seeds are strongly pungent and aromatic in its taste.

SMOKING-HAZARDOUS TO OUR HEALTH: ‘AN OVERVIEW’

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About Authors:
Babu Lal
Department of Pharmacy,
Tirupati College of Polytechnic & Pharmacy,
Sardulgarh Road, Ratia, Dist. Fatehabad (Haryana), Pin-125051
lab_85@rediffmail.com

Abstract:
The word of smoking, drinking smoke is very famous all over the globe. The practice of Dhumrapana is commonin human beings from the last two thousand year’s to induce consciousness. Soon, the recreational use of tobacco became a part of the elite culture throughout the world and shows remarkable value in large scale productivity (multibillion dollar business)[1]. Botanically, tobacco is achieved from the dried leaves of Nicotiana tobacum Linn (var.macrophyll, N. chinensis Fisch), commercially cultivated on small scale tolarge extent in China, United States and India. The tobacco contains pyridine-piperidine type of alkaloids, among which the most prominent is nicotine. Nicotine, well known as natural botanical insecticide weighs 0.6-3.0% of dried leaves which is synthesized in roots and accumulated in the leaves. Smoking was practiced by early priests to diagnose, heal the bizarrepersons and to fend off evil spirits. As time passes, smoking tobacco becomes more than just a ritualistic comportment. However, the pattern has now been endorsed to the growing numbers of ailments, birth defects, and deaths. Worldwide, approximate 4.9 million and alone in United State (US), smoking is the reason for 434,000 deaths per year [2] and every day14,000 peoples diebecause of smoking-related diseases. Today, medical studies have proven that smoking tobacco is among the leading sources of lung cancer, heart attacks, chronic obstructive pulmonary disease(COPD), and erectile dysfunctionand can also lead to teratogenic effect. Moreover, active smokers are not the only ones in severe danger but people lives around them, bystander’s or passive smoker affected much more accumulating the health-related effect brought about by the emitted dangerous chemicals (smoke) from a cigar or cigarettes. In fact, 33 percent of the nonsmoker population in the US is exposed with environmental cocktail of tobacco smoke [3].

JAN AUSHADHI STORE: A NEW APPROACH IN PROVIDING LOW COST DRUGS TO THE PUBLIC

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About Authors:
Rohit Gujarati, T.M.Pramod Kumar, Parasiya Sachin R.
Pharmaceutical Regulatory Affairs Group, Dept. of Pharmaceutics,
JSS College of Pharmacy, JSS University, S.S Nagar, Mysore-570015, Karnataka, India
rohitgujrati@gmail.com

Abstract
India has one of the best developed pharmaceutical industries, and produces about 20 per cent of the world’s drugs. Currently many top Indian companies are exporting generic drugs worth Rs 45,000 crore every year to many countries including the US and Europe. But ironically, drugs are beyond the reach of people in India itself, especially the poor, because their prices are very high. It is not that the cost of R&D and manufacturing is high, but that the profit margins are exorbitant and in many cases exploitative, which can be explained by reasons like, lack of proper regulation on price control (except for few DPCO drugs), prescription made by the doctors, lack of awareness in public about the generic drugs.

Government of India is taking certain steps in providing cost effective drugs to the public without compromising with the quality of the medicines. Recently Union government and regulatory bodies appear to be serious in ending the pharma-doctor nexus and curb unethical marketing practices. In its latest effort, the Medical Council of India (MCI) has directed doctors, hospitals and medical colleges to prescribe generic medicines as far as possible. This has not benefited much to the public. This Paper give a brief scenario about the various measures taken by the Govt. of India to scale down the rates of high cost medicines, among which, the concept of “jan aushadhi”, which talks about various measures taken by the Govt. of India on increasing the availability of the generic drugs throughout the country, has been highlighted.

A PARADIGM SHIFT IN DRUG REGULATIONS IN TAIWAN

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About Authors:
*Parasiya Sachin kumar R., Balamuralidhara V., Pramod Kumar T.M., Rohit Gujarati, Abhisek Shukla, Vandana Kshatri
Pharmaceutical Regulatory Affairs Group, Dept. of Pharmaceutics,
JSS College of Pharmacy, JSS University, S.S Nagar, Mysore-570015, Karnataka, India
*sachin_patel2007@yahoo.com

Abstract
Across Asia, a convergence of economic trends, government policies and greater awareness among the general public of healthcare issues has created an environment that is poised for dramatic growth and change. Taiwan, for instance, can be taken as an example. Taiwan has one of Asia's most highly-praised healthcare systems with excellent provision of healthcare and key health outcomes. Nevertheless, the government is facing new pressures for public healthcare reforms as result of a rapidly ageing population and rising healthcare costs. This paper provides an introductory overview of Taiwan’s sudden changes in its drug regulations due to TFDA (The Taiwan Food and Drug Administration) establishment in 2010, TFDA of the Department of Health (DOH) made an advance announcement about the “amendment draft of the Provisions Governing the Registration and Market Approval of Drugs”, which amends a total of 40 Articles. Without impeding the quality, safety and therapeutic effect of drugs, most of the amended Articles are about simplification of application procedures and loosening of regulations for drug registration and market approval. Regulations loosened are imposed on new drugs, radioactive drugs, allergenic drugs and drugs for export that is intended to accelerate the process to sell new drugs on the market and promote the export of domestically manufactured drugs. As a result of these changes in regulations many pharmaceutical MNCs and local manufacturers explored their business in Taiwan due to quick approval of their NDAs and gained more flexibility in the local market. To support Taiwan's generic drug industry, DOH has also decided to take measures to simplify and reduce the ANDA application time.

FRUITS & VEGGIES GRANDIOSE ON PESTICIDES

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Various investigations and concerning research reports reveal that although a Pesticides Act exists to safeguard consumer interest, there is no MRL (Maximum Residue Level) in place or regulations to enforce it. Nearly every food item from rice to veggies and fruits available in the market are contaminated with poisonous pesticides, authorities caution. Pesticides and insecticides could be detrimental to people’s immune and reproductive systems. It can even lead to infertility. Developmental toxins’ in these chemicals may adversely affect the development in children. They may also act as endocrine disrupters, leading to hormonal imbalances. These chemicals are also not biodegradable(able to decompose naturally). As such, they persist for a long time and get transferred into the food chain. This means that overtime, they get deposited in the human body.

GENERIC DAVIDS AND INNOVATOR GOLIATHS

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ABOUT AUTHOR:
Amit Gangwal
Department of Pharmacognosy,
Smriti college of pharmaceutical education, Indore, Madhya Pradesh, India
gangwal.amit@gmail.com

ABSTRACT
Patents provide an incentive to the pharmaceutical industry to invest in the development of new medicines to treat diseases that are currently untreatable or incurable, and provide options when patients develop resistance to older drugs. Around the world it has been a challenge for last one or two decades to innovate concepts and mechanisms to hasten the drug development schemes/process, while augmenting dereplication ways in a full proof manner to save time, man power and financial input. High failure rate at any stage in drug development process is bothering and evoking various tools to be discussed like never before. The pharmaceutical industries world over, are in a period of crisis due to the poor number of approved drug molecules relative to the high levels of R&D investment. The drug industry is facing major scientific and strategic challenges. Moreover competition from generic giants is giving tough challenge to established products owing to end of patent rights. The concerns are further aggravated by couple of decisions announced by Indian courts (Nexavar® followed by long time pending battle of Gleevac®). These two decrees by Indian courts were not ruled in the favor of pharma giants; Bayer and Novartis respectively. Millions are dying in various part of world, owing to their inability to purchase the Elite Drugs, because of intellectual property rights. In this article various pros and cons have been discussed pertaining to generic medicines and patent fights of innovators world over.

PLAGIARISM: A GROWING CONCERN IN SCIENTIFIC COMMUNITY

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Let us first of all know about plagiarism and how it is different from copyright piracy. Plagiarism word is derived from Latin word plagiaries which mean stealing someone else’s work1. According to oxford dictionaries its literal meaning is “the practice of taking someone else’s work or ideas and passing them off as one’s own”2. Wikipedia defines plagiarism as “the wrongful appropriation and purloining and publication of another author's language, thoughts, ideas, or expressions, and the representation of them as one's own original work”1. The word plagiarism is different from copyright piracy3. Copyright piracy is unauthorised doing anything, the exclusive right to do which is with copyright owner or reproduction, sale or hiring in any form4,5 whereas plagiarism is the failure of giving credit to original author5 but both are infringements of copyright (under Indian Copyright Act, 1957) and hence crime. Unauthorised reproduction, sale or hiring is not infringement of copyright after expiry of the copyright protection period which varies nation-wise (minimum requirement under Berne Convention is 50 years and 60 years in case of India, post mortem of copyright owner) but under author’s moral rights his authorship and control over the work is forever and no one can represent it as his/her own original work6. If someone is doing so it would be plagiarism and hence serious ethical offense and crime.

GREENER ITINERARY TO THWART PHARMACY - EFFLUENCE

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ABOUT AUTHOR:
Raaz K Maheshwari
Department of Chemistry, SBRM PG Govt College,
Nagaur, Rajasthan
drraazgreenchemacs@gmail.com

ABSTRACT
The use of PPCPs is on the rise on the globe. PPCPs enter into the environment through individual human activity and as residues from manufacturing, agribusiness, veterinary use, and hospital and community use. Individuals may add PPCPs to the environment through waste excretion and bathing as well as by directly disposing of unused medications to septic tanks, sewers, or trash. Because PPCPs tend to dissolve relatively easily and don’t evaporate at normal temperatures, they often end up in soil and water bodies. Some PPCPs are broken down or processed easily by a human or animal body and/or degrade quickly in the environment. However, others do not break down or degrade easily. The likelihood or ease with which an individual substance will break down depends on its chemical makeup and the metabolic pathway of the compound. Varying concentrations of drugs found in water sources can have ill effect on the aquatic life and human health. For pharmaceutical pollution, the solution calls upon all health care sectors to participate in preventing pharmaceutical pollution. Green Pharmacy aims at zero pharmaceutical waste in our environment. It offers an opportunity for social action that will greatly benefit our environment at all levels of our society. It encourages health providers and clients to focus on healthy lifestyle and prevention to ensure their well-being through regular wellness practices. It provides education and opportunity for everyone involved with the life cycle of medicine to participate in reducing pharmaceutical pollution. With relatively simple yet firm commitments to change our habits, becoming stewards of medicine rather than consumers of medicine we effectively become part of the solution. This review paper delineates about the powerful approaches of green pharmacy that provides comprehensive solution to pharmaceutical pollution affecting much of well being on globe. Research to date points to the ubiquity of PPCPs in aquatic environments. Existing wastewater treatment facilities are inadequate and aren’t designed to remove them from the waste stream. Our current system of quantifying their toxicological effects is inadequate. Now is the time to prevent further harm to living organisms and the environment.

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