Discovery of small molecule inhibitors targeting NLRP3-mediated signaling in ALI, ARDS. Discovery and preclinical development of anti-virals for Covid-19 and other diseases.
BRIC-Translational Health Science and Technology Institute (THSTI) is an Institute of the Biotechnology Research and Innovation Council, Department of Biotechnology, Ministry of Science & Technology, Govt. of India.
Synthesis of Polymer, polymeric nanoparticles, Characterization of physicochemical parameters Determination of anticancer therapeutic effect in the in vitro assay systems Validation of the in vitro results in the in vivo animal models of bacterial meningitis.
Studying the ribosomal RNA diversity, functional relevance of rRNA processing factor 2 in ribosome biogenesis, root, shoot development and drought stress tolerance in rice.
Routine cell culture, differentiation of cells, transfection of cells, lentivirus preparation and transduction, analysis by western blotting, qPCR, ChIP, microscopy, protein purification and various biochemical assays and kits
M.Pharma or Ph.D. in any branch of Life Sciences or Biotechnology with at least two peer-reviewed international publication in Science Citation indexed; experience in molecular biology related techniques including PCR, recombinant DNA cloning techniques, plant transformation, and library preparation methodologies for NGS.
Development of imine reductase based biocatalytic platoform for the synthesis of chiral amines building blocks for drug discovery and developmental applications
DST-WTI funded Project entitled Development and performance demonstration of single-pass antifouling reverse osmosis desalination membrane and modules in seawater desalination plant