Skip to main content

Andhra Pradesh

Pharma Courses
  • QUALITY OF WATER FOR PHARMACEUTICAL USE: AN OVERVIEW

    About Authors:
    YASWANTH ALLAMNENI1*, NAVYA ALLAMNENI2, P DAYANANDA CHARY1, G VIJAY KUMAR3, ARUN KUMAR KALEKAR1, PAVAN KUMAR POTTURI1
    1Research and Development Department, Natco Pharma Limited, Kothur, Mahaboobnagar,Andhra Pradesh – 509228.
    2Department of Pharmaceutical Technology, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Guntur, India.
    3Principal, A.K.R.G college of Pharmacy, Nallagerla, West Godavari, Andhra Pradesh.

    *yaswanthallamneni@gmail.com

    ABSTRACT
    Water is widely used as a raw material, ingredient, and solvent in the processing, formulation, and manufacture of pharmaceutical products, active pharmaceutical ingredients (APIs) and intermediates, compendial articles, and analytical reagents. This review discusses, primarily from a microbiological aspect, the review and evaluation of high purity water systems that are used for the manufacture of drug products and drug substances. It also includes a review of the design of the various types of systems and some of the problems that have been associated with these systems. As with other guides, it is not all-inclusive, but provides background and guidance for the review and evaluation of high purity water systems. The main objective of this review was to provide guidance to the industry on the pharmaceutical use of different grades of water in the manufacture of active pharmaceutical ingredients and medicinal products for human and veterinary use. This guidance is not intended to cover situations where, for example, medicinal products are prepared extemporaneously or where preparations are reconstituted or diluted with water prior to use by pharmacist (eg. Oral antibiotic mixtures) or in the case of veterinary products by the user (eg. Sheep dips).

  • Dr. L.H. Hiranandani College of Pharmacy invites for post of Principal

    Dr. L.H. Hiranandani College of Pharmacy (Linguistic Unaided Minority Educational Institution) C.H.M College Campus, Near Railway Station, Ulhasnagar - 421 003. The post is open to all. However candidates from any other category can apply for the posl. Reservation for women & disabled persons will be as per rules. Candidate having knowledge of Marathi will be preferred.

  • Freshers invited to work as Scientific Writer in PAREXEL India | Degree and a higher degree in Life Sciences, Pharmacy, or Medicine

    PAREXEL International is a growing, fast-paced, global Clinical Research Organization (CRO) that has helped bring to market 49 of the top 50 selling pharmaceuticals. In fact, we have worked with all 10 of the world's top 10 pharmaceutical companies.

  • Career opportunity to join in Virchow Biotech as Production Executives - 30 posts | freshers may apply

    Virchow Biotech Private Limited (VBPL), an innovative biotechnology company headquartered at Hyderabad, India. VBPL also has offices located in the United States of America ( at Nashville, Tennessee)

  • Openings for Territory Managers in Wockhardt - south zone

    Wockhardt today, is distinguished by a strong and growing presence in the world's leading markets, with more than 65% of its revenue oming from Europe and the United States. Wockhardt's market presence covers formulations, biopharmaceuticals, nutrition products, vaccines and active pharmaceutical ingredients (APIs).

  • Fly USA with InvaGen Pharmaceuticals | Require Analytical Development / QC (Research Scientists), Sr. QA Associate / Manager, Sr. Regulatory Associate, Manufacturing Supervisor, Manager- Process Development

  • VJ's College of Pharmacy invites Professor, Associate professor, Assistant professor in all branches of pharmacy

    VJ's college of pharmacy was established in the year 2007 by pharmcy professionals at Rajahmundry in East Godavari District, Andhrapradesh. the college is offering B.Pharm, M.Pharm (Pharmaceutics, Pharmaceutical Analysis & Pharmacology)

  • Applications invited for Research Specialist position, sponsored by the National Institute of Animal Biotechnology at University of Hyderabad | Require M.Sc / IM.Sc / M.Tech / M.Pharm

    Applications are invited from qualified individuals for Research Specialist position, sponsored by the National Institute of Animal Biotechnology (NIAB-DBT) project entitled “Studies on epigenetic regulation during lactation and its impact on milk biosynthesis” (NIAB/CP/107/2012).

    Post: Senior Research Fellow

    [adsense:336x280:8701650588]

  • ENHANCEMENT OF DISSOLUTION OF POORLY WATER SOLUBLE DRUG USING SUPER DISINTEGRANTS BY KNEADING METHOD

    About Authors:
    YASWANTH ALLAMNENI1*, PAVAN POTTURI1, RAJKUMAR NULU2, RAVADA RAMESH3, P DAYANANDA CHARY1, ARUN KALEKAR1.
    1Research and Development Department, Natco Pharma Limited, Kothur, Mahaboobnagar,Andhra Pradesh, India-509228.
    2Research and Development Department, Aurobindo Pharma Ltd., Hyderabad, Andhra Pradesh, India.
    3HOD, Dept. of Pharmaceutics, Dr. H.L.T. College of pharmacy, Kengal, Channapatna, Banglore(R).

    *yaswanthallamneni@gmail.com

    ABSTRACT
    The aim of this study was to investigate the influence of superdisintegrants on the dissolution properties of a poorly water-soluble drug from complexes prepared by kneading method. Ketoprofen was employed as a model drug. Solid dispersions prepared by kneading method exhibited higher dissolution rate and DE30 values in each case. Ketoprofen tablets were prepared by direct compression technique using microcrystalline cellulose as a directly compressible vehicle. The formulated tablets were evaluated by different In Process Quality Control tests, content uniformity and in vitro drug release study. The FTIR spectra’s study revealed that there were no interaction between polymers and drug. All the tablets formulated employing solid dispersions in superdisintegrants gave rapid and higher dissolution of Ketoprofen when compared to that of Ketoprofen plain tablets. Ketoprofen dissolution from all the tablets followed first order kinetic with correlation coefficient ‘r’ above 0.9470. All dissolution parameters (k1, DE30 and T30) indicated rapid and higher dissolution of Ketoprofen from tablets formulated employing its solid dispersions in superdisintegrants when compared to plain tablets.

  • Vacancy for Director at NIPER Rae Bareli, Hajipur, Guwahati, Kolkata, Ahemedabad and Hyderabad

    Government of India has set up six new National Institutes of Pharmaceutical Education and Research (NIPERs) under the aegis of Ministry of Chemicals and Fertilizers, Department of Pharmaceuticals, at Rae Bareli, Hajipur, Guwahati, Kolkata, Ahmedabad and Hyderabad. These are presently being run with the help of Mentor Institutes. The Institutes are required to be established on their own.

Subscribe to Andhra Pradesh