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  • A REVIEW ON PHARMACEUTICAL ANALYSIS OF MASS SPECTROSCOPY

    ABOUT AUTHORS:
    G.Venkateswarlu*, M.Muthukumaran, B.krishnamoorthy, Ameren nishat
    Montessori Siva Sivani Institute of Science & Technology College of Pharmacy-Mylavaram,
    Vijayawada, Andhra pradesh-521230
    *venkateswarlu460@gmail.com

    ABSTRACT
    The goal of this review is to provide a guide for understanding current MS technology. Mass spectrometry (MS) has progressed to become a powerful analytical tool for both quantitative and qualitative applications. Proteomics research, in particular, increasingly depends on MS technologies. Basically, any information gathered from a mass spectrometer comes from the analysis of gas-phase ions. There are three main components of a mass spectrometer: an ionization source, a mass analyzer and a detector the name ‘mass spectrometry’ is a misnomer of sorts. The mass is not what is measured; instead, mass spectrometry determines the mass-to-charge (m/z) ratio or a property related to m/z .A mass spectrum is a plot of ion abundance versus m/z, although in many cases the x-axis is labelled ‘mass’ rather than m/z. The spectrum is presented in terms of Daltons (Da) per unit charge The ability of mass spectrometry analyzing proteins and other biological extracts is due to the advances gained through the development of soft ionization techniques such as electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI) that can transform biomolecules into ions. Regardless of the ionization source, the sensitivity of a mass spectrometer is related to the mass analyzer where ion separation occurs.  

  • Opening for M.Pharm, M.Sc as Senior Research Fellow in National Institute of Nutrition

    National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr. McCarrison as its first Director. It was shifted to Hyderabad in 1958.

  • DEVELOPMENT AND VALIDATION OF A REVERSED-PHASE HPLC METHOD FOR ASSAY OF AZITHROMYCIN IN POWDER FOR ORAL SUSPENSION

    About Author:
    Swapna.G*
    Department of pharmaceutical Pharmaceutical & Quality Assurance,
    Nirmala College of Pharmacy, Mangalagiri, Atmakuru, Guntur -522 203.
    *swapna.goday.gs@gmail.com

    Abstract
    A  simple,  precise  and  accurate  reversed phase liquid chromatographic method has been  developed  for  the  assay  of  azithromycin  in  powder  for oral suspension. The chromatographic separation was achieved on a Asahipak ODP 40 E(250 mm × 4.6 mm, 5 μm)  analytical  column.  A  mixture  of  methanol–ammonium dihydrogen phosphate (0.05M)  (30:70, v/v)  (pH 9.0)  was  used  as  the  mobile  phase,  at   a  flow  rate  of 1.5 mLmin-1  and  detector  wavelength  at  210 nm. The retention time of  azithromycin was  found to be at  8.0 min. The validation of the proposed method was carried out for specificity, linearity, accuracy, precision, robustness and stability indicating assay. The linear  dynamic range is from   382–1208 μgmL-1 for  azithromycin. The percentage recovery  obtained  for  azithromycin is 101.0%.  The developed method can be used for pharmaceutical dosage form and  in process testing.

  • Work as Senior Team Member - Quality Control in Mylan

    Mylan is one of the world’s leading generics and specialty pharmaceutical companies, providing products to customers in more than 150 countries and territories. The company maintains one of the industry’s broadest and highest quality product portfolios, which is regularly bolstered by an innovative and robust product pipeline.

  • PRELIMINARY CHARACTERIZATION OF ROCK SALT IN PRESENCE OF CITRIC ACID BY FTIR SPECTROSCOPY

    ABOUT AUTHOR:
    BINDU.S
    ANNAMACHRYA COLLEGE OF PHARMACY,
    RAJAMPET,KADAPA Dist, A.P, INDIA.
    sirasalabindupharmacy@gmail.com

    INTRODUCTION
    Rock salt, also known as halite is the naturally occurring crystalline salt. It is the mineral form of sodium chloride or the table salt that we use. However, rock salt does not look like the regular table salt. Instead, it naturally forms in large isometric crystals. Moreover, rock salt can be white like table salt or it can be red, orange, yellow or blue in color. The color of rock salt basically depends on the amount, and the kind of impurities present in it. Along with sodium, rock salt contains many other minerals including, calcium, zinc, iron, magnesium, potassium, copper and several other trace minerals. Like table salt, rock salt too has great many uses. rock salt in massive bags for the purpose of keeping down ice on the roads in the winter.

  • DISCUSSION ON BIOREMEDIATION AND ITS APPLICATIONS:AN OVERVIEW

    About Authors:
    Lohithasu Duppala*1, Madhu priya Damuluri,1 Anilkumar vadda2
    1GITAM Institute of Pharmacy, GITAM University, visakhapatnam, Andhra Pradesh, India-530045.
    2AVANTHI Institute of pharmaceutical sciences, pharmacology, visakhapatnam, Andhra Pradesh,India-530045.
    *lohithasupharma@gmail.com

    ABSTRACT:
    The environmental biotechnology employs the application of genetic engineering to improve the efficiency and cost which is essential to the future wide spread exploitation of microorganisms to reduce the environmental burden of toxic substances. Now a days it can be achieved by bioremediation, is the process by using microorganism metabolism to remove pollutants and organic substances. It may be employed to attack specific soil contaminants, such as degradation chlorinated hydrocarbons by bacteria.

  • DISCUSSION ON BIOSENSORS AS AN ANALYTICAL DEVICE AND ITS APPLICATIONS IN VARIOUS FIELDS : A RECENT REVIEW

    About Authors:
    Lohithasu Duppala*1, Madhu priya Damuluri1, Anilkumar vadda2
    *1GITAM Institute of Pharmacy, GITAM University,
    visakhapatnam, Andhra Pradesh, India-530045.
    2AVANTHI Institute of pharmaceutical sciences, pharmacology,
    visakhapatnam, Andhra Pradesh, India-530045.
    *lohithasu@gmail.com, +91-9491894432.

    INTRODUCTION
    A biosensor is a measuring device that uses an immobilized agent to detect a chemical compound concentration or activity by converting a biological response into measurable signal as workable signal form. It is a self-contained analytical and measurable device that incorporates a biologically active  material in contact with tranducer  or detecting element to detect the concentration or activity of chemical compounds in a analyte  or sample. The obtain electrical signal it produces carries the necessary information about the process under investigation.1

  • Career opportunity for fresh B.Pharm, M.Pharm to work as Pharmacy Analyst @ ITC Infotech - 50 posts

    ITC Infotech, a global IT services company, is a fully-owned subsidiary of ITC Limited, the US$ 7 billion diversified conglomerate. ITC Limited is rated among the ‘World's Most Reputable Companies’ by Forbes magazine and among ‘India's Most Valuable Companies’ by Business Today.

  • HEPATOPROTECTIVE ACTIVITY A REVIEW

    About Author:
    SOWJANYA GUDUGUNTLA,
    M.Pharmacy, Pharmaceutical Chemistry department
    ANNAMACHRYA COLLEGE OF PHARMACY,
    RAJAMPET, KADAPA Dist, A.P, INDIA.

    Sowjanya09.pharma@gmail.com

  • Job for M.Pharm / M.Sc as Research Assistant in University of Hyderabad

    The University of Hyderabad (UoH), one of the major institutions of higher education in India is largely devoted to postgraduate studies and is widely known for its excellence in research and for its distinguished faculty. Founded in 1974 with Prof. Gurbaksh Singh as its first Vice Chancellor, UoH - also known as Hyderabad Central University or HCU- has emerged as a leading centre of teaching and research.

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