Cancer scientists say they have engineered a new type of super-strong antibody which could be used to boost the immune systems of patients fighting the disease.
Researchers have uncovered multiple new genes and genetic pathways that could lead to repurposing hundreds of existing drugs for osteoarthritis, the most common form of arthritis. The research, which analyzed data from nearly 2 million people in diverse populations worldwide, was recently published in Nature. It represents an extensive genetic exploration of osteoarthritis, a condition affecting over 600 million people globally.
A highly sensitive bone marrow test could double survival rates for some groups of younger adults with Acute Myeloid Leukaemia by helping doctors identify if they might relapse up to three months earlier. The patient-specific molecular test can detect low levels of leukaemia cells in the body, known as minimal residual disease, which when left untreated causes the disease to relapse.
A preclinical study from scientists at Scripps Research finds that a drug already FDA-approved for treating inflammatory conditions may help reduce both alcohol intake and pain sensitivity two issues that commonly co-occur with alcohol use disorder (AUD).
Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these immune proteins can do more than that: They also activate other components of the immune system, which then go to work to clear an infection. A new study from Scripps Research explores the factors that influence how effectively antibodies engage specific immune cells.
Team of Young researchers, still in Indian school, developed a portable, electricity-free refrigeration unit using a salt solution to keep vaccines and other temperature-sensitive materials cool. Team consisting of Dhruv Chaudhary, Mithran Ladhania, and Mridul Jain, is known for their work on Thermavault, a device designed to transport vaccines, medicines, and even transplant organs.
A study published in the American Journal of Human Genetics by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital provides solutions to the pressing need to identify factors that influence Alzheimer’s disease (AD) risk or resistance while providing an avenue to explore potential biological markers and therapeutic targets.
In the global carbon cycle microorganisms have evolved a variety of methods for fixing carbon. Researchers from Bremen and Taiwan have investigated the methods that are utilized at extremely hot, acidic and sulfur-rich hydrothermal vents in shallow waters off the island of Kueishantao, Taiwan.
Antiseizure medication is usually prescribed for people with the condition. However, for one in three people with epilepsy around 20 million individuals worldwide, current antiseizure medications are ineffective. This means that people will continue to have seizures despite taking medication – a condition called ‘drug resistance.
In a paper in the Journal of Diabetes Science and Technology, researchers at Stevens Institute of Technology offer a new approach: a data-sparse model capable of accurately predicting individual glycemic responses with no need for blood draws, stool samples, or other unpleasant testing. The key to their approach? Keeping track of what people actually eat.