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  • FDA clears IND for clinical trial testing switchable CAR-T therapy in patients with autoimmune diseases, without chemotherapy
    14 April 2025

    FDA clears IND for clinical trial testing switchable CAR-T therapy in patients with autoimmune diseases, without chemotherapy

    Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy in patients with autoimmune conditions. Patient recruitment for the phase 1 trial will begin soon.
  • 10 April 2025
    Starch-based microplastics could cause health risks in mice, study finds
    Wear and tear on plastic products releases small to nearly invisible plastic particles, which could impact people’s health when consumed or inhaled. To make these particles biodegradable, researchers created plastics from plant starch instead of petroleum.
  • 10 April 2025
    Treatment for mitochondrial diseases within reach
    Mitochondrial diseases caused by POLG mutations vary in severity. In young children, these diseases can quickly result in brain damage and life-threatening liver problems while others suffer muscle weakness, epilepsy, and organ failure later in childhood. POLG mutations recently received media attention when Prince Frederik of Nassau in Luxembourg died in March 2025 at just 22 years of age.
  • 9 April 2025
    HKU State Key Laboratory and InnoHK CVVT Successfully Develop Nasal Spray H5N1 Avian Influenza Vaccine
    The State Key Laboratory for Emerging Infectious Diseases at the University of Hong Kong and the InnoHK Centre for Virology, Vaccinology and Therapeutics have pioneered an influenza virus vector-based nasal spray vaccine platform and developed a nasal spray H5N1 avian influenza vaccine.
  • 9 April 2025
    Students lead breakthrough study on diabetes drugs and dementia risk
    Two undergraduate medicine students at University of Galway have led a major study examining how cardioprotective glucose-lowering therapies - medications that lower blood sugar and reduce the risk of heart disease in people with diabetes - affect the risk of developing dementia.
  • 8 April 2025
    New study investigates effects of ADHD medications on the heart
    A new study led by the University of Southampton has found that medications for ADHD have overall small effects on blood pressure and heart rate after weeks or a few months of use. There have been concerns about the side effects of ADHD medications but the new findings, coupled with other studies, suggest that the benefits of taking these medications outweigh the risks, while highlighting the need for careful monitoring.
  • 8 April 2025
    Researchers Discover Way to Predict Treatment Success for Parasitic Skin Disease
    Nearly one million people worldwide are plagued annually by cutaneous leishmaniasis, a devastating skin infection caused by the Leishmania parasite. Predominantly affecting vulnerable populations in tropical and subtropical regions like North Africa and South America, this disease thrives in areas marked by malnutrition, poor housing and population displacement.
  • 8 April 2025
    Tulane researchers use AI to improve diagnosis of drug-resistant infections
    Drug-resistant infections especially from deadly bacteria like tuberculosis and staph are a growing global health crisis. These infections are harder to treat, often require more expensive or toxic medications and are responsible for longer hospital stays and higher mortality rates.
  • 5 April 2025
    A rice sized pacemaker that heals and dissolves, need no surgery

    Northwestern University engineers have developed a pacemaker so tiny that it can fit inside the tip of a syringe — and be non-invasively injected into the body.

    Although it can work with hearts of all sizes, the pacemaker is particularly well-suited to the tiny, fragile hearts of newborn babies with congenital heart defects.

  • 3 April 2025
    Organogold (III) complex accumulates in mitochondria of lung cancer cells

    Precious metals are not merely ornaments; they are also important components of pharmaceuticals, like the antitumor drug cisplatin. Recently, the search for alternatives with improved activity has begun to focus on gold. In the journal Angewandte Chemie, a French research team has now published the first study about the speciation and distribution of an organogold(III) complex in cancer cells and reveals how specially designed “organogold” complexes might open exciting avenues for fighting cancer. 

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