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  • Repurposing FDA-approved drugs may help combat COVID-19

    Several FDA-approved drugs including for type 2 diabetes, hepatitis C and HIV significantly reduce the ability of the Delta variant of SARS-CoV-2 to replicate in human cells, according to new research led by scientists at Penn State. Specifically, the team found that these drugs inhibit certain viral enzymes, called proteases, that are essential for SARS-CoV-2 replication in infected human cells.

  • Experimental combinatorial therapy eliminates an incurable brain tumour

    A study recently accepted for publication in The Journal of Clinical Investigation describes a new and effective therapy to treat glioblastoma: the concomitant use of ADI-PEG20 together with focal brain radiotherapy. This double treatment completely eliminated the tumour in the animal models used in the study. This study was carried out by researchers from the Institute of Biomedicine of Seville: Dr. Manuel Sarmiento Soto, Dr. Juan García Revilla, and Dr. José Luis Venero, in collaboration with Dr. Nabil Hajji and Dr. Nel Syed of Imperial College London.

  • Development of nanoengineered bacteria for cancer optotheranostics

    There is substantial interest regarding the understanding and designing of nanoengineered bacteria to combat various fatal cancerous diseases. However, conventional nanotechnological approaches adopt genetic manipulation for attenuating and improving the efficacy of bacteria. In addition, complicated chemical reactions were essential in the previous approaches.

  • NIAB discover potential biomarker for Japanese encephalitis virus

    NIAB discover potential biomarker, NS 1 protein for Japanese encephalitis virus. Non-Structural 1 protein, a potential diagnostic biomarker for Japanese encephalitis virus. A diagnostic biomarker refers to a biological parameter that aids the diagnosis of a disease and may serve in determining disease progression or success of treatment.

  • Guduchi is safe and does not produce any toxic effects says, Ayush Ministry

    Certain sections of the media have falsely linked again Giloy/Guduchi to liver damage. The Ministry of Ayush reiterates that Giloy/Gudduchi (Tinospora cordifolia) is safe and as per available data, Guduchi does not produce any toxic effect.

  • Breakthrough, US woman got cured from HIV by stem cell transplant

    A U.S. patient with leukemia has become the first woman and the third person to date to be cured of HIV after receiving a stem cell transplant from a donor who was naturally resistant to the virus that causes AIDS, researchers reported.

    The oral abstract was presented at CROI 2022, the Conference on Retroviruses and Opportunistic Infections.

  • Heart attack survivors may be less likely to develop Parkinsons disease

    People who have had a heart attack may be slightly less likely than people in the general population to develop Parkinsons disease later in life, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

  • Unexpected findings detailed in new portrait of HIV

    Using powerful tools and techniques developed in the field of structural biology, researchers at the University of Washington and Scripps Research have discovered new details about the human immunodeficiency virus, HIV. The findings bring into focus the basic architecture of the virus just above and below its surface and may help in the design and development of a vaccine that can protect against AIDS.

  • A new multipurpose on-off switch for inhibiting bacterial growth

    Researchers in Lund have discovered an antitoxin mechanism that seems to be able to neutralise hundreds of different toxins and may protect bacteria against virus attacks. The mechanism has been named Panacea, after the Greek goddess of medicine whose name has become synonymous with universal cure. The understanding of bacterial toxin and antitoxin mechanisms will be crucial for the future success of so-called phage therapy for the treatment of antibiotic resistance infections, the researchers say. The study has been published in PNAS.

  • A Microbial Compound in the Gut Leads to Anxious Behaviors in Mice

    A Caltech-led team of researchers has discovered that a small-molecule metabolite, produced by bacteria that reside in the mouse gut, can travel to the brain and alter the function of brain cells, leading to increased anxiety in mice. The work helps uncover a molecular explanation for recent observations that gut microbiome changes are associated with complex emotional behaviors.

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