Research News

A recent study from the lab of the University of Kentucky’s Sanders-Brown Center on Aging Director Linda Van Eldik, Ph.D., has been published in PLOS ONE. The work centers around the idea that various anti-inflammatory drugs could be effective treatments for Alzheimer’s disease (AD). This study focused on a protein known as p38. Many labs have been working with this protein as a potential target for drug development to treat Alzheimer’s disease and other conditions with neuroinflammatory dysfunction.

ChatGPT’s responses to people’s healthcare-related queries are nearly indistinguishable from those provided by humans, a new study from NYU Tandon School of Engineering and Grossman School of Medicine reveals, suggesting the potential for chatbots to be effective allies to healthcare providers’ communications with patients.

An NYU research team presented 392 people aged 18 and above with ten patient questions and responses, with half of the responses generated by a human healthcare provider and the other half by ChatGPT.

Women have used birth-control pills since the 1960s, but researchers still do not know everything about the body's complex reaction to the small, hormone-laden pill.

Researchers from Aarhus University and the United States have studied the stress response of 131 young women when having a blood sample taken. Some of the women were on birth-control pills, while others were not. The researchers specifically measured the levels of the stress hormone ACTH in the women’s blood.

Scientists have designed an AI tool that can rapidly decode a brain tumor’s DNA to determine its molecular identity during surgery - critical information that under the current approach can take a few days and up to a few weeks.

Knowing a tumor’s molecular type enables neurosurgeons to make decisions such as how much brain tissue to remove and whether to place tumor-killing drugs directly into the brain - while the patient is still on the operating table.

For the first time, scientists have shown that gut bacteria differences are associated with later development of juvenile idiopathic arthritis, a debilitating rheumatic childhood disease, and that these differences are present years before the disease is diagnosed.

Older people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer’s disease and related dementias compared to people who have steady levels, according to new research published in the July 5, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. While the study found a link, it does not prove that fluctuating levels of cholesterol and triglycerides cause dementia.

Nearly 700,000 people in the United States die from heart disease every year, and one-third of those deaths result from complications in the first weeks or months following a traumatic heart-related event.

Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study published June 22 in the New England Journal of Medicine. The new standard is more effective at preventing GVHD and came with less side effects, compared with the current gold standard.

A team of researchers at Baylor College of Medicine is gaining ground in their search for solutions to the global problem of bacterial antibiotic resistance, which was responsible for nearly 1.3 million deaths in 2019.