The euphoric feeling that gives runners a motivational boost in the middle of their workout is in part modulated by the satiety hormone leptin, a new study has found. The study at the University of Montreal Hospital Research Centre (CRCHUM) shows that the "runner's high" phenomenon is caused by dopamine, an important neurotransmitter for motivation. "We discovered that the rewarding effects of endurance activity are modulated by leptin, a key hormone in metabolism.



