Kota

ECHS, Kota invites for post of Pharmacist

Retired Armed Forces personnel till 2002 could avail medical facilities only for specific high cost surgery/treatment for a limited number of diseases covered under the Army Group Insurance(Medical Branch Scheme) (AGI(MBS)) and Armed Forces Group Insurance Scheme(Management Information System) (AFGIS (MIS)) schemes. These medicare schemes could provide some relief to the ESM, but it was not a comprehensive scheme as compared to and available for other Central Government Employees.

A BRIEF REVIEW ON SUSTAINED RELEASE MATRIX TABLETS OF BACLOFEN

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ABOUT AUTHORS:
Singh Surya Pratap*, Soni Shankar Lal, Khinchi Mahaveer Prasad, Gulia Ritu, Namdev Abhisek
Department of pharmaceutics, Kota College of  Pharmacy,
Ranpur, Kota, Rajasthan, India
sp.kota91@gmail.com

ABSTRACT
The objective of the present study was to focus on sustained release matrix tablets of baclofen, for treatment of spastically resulting from multiple sclerosis, flexor spasm and muscular rigidity. Designing effective therapies for Spinal cord injury (SCI) has been a challenging problem because spinal cord injuries are heterogeneous in causality, severity and location of injury.

Effective drug therapy for Spinal cord injury (SCI) first became a reality in 1990 with the finding that the steroid drug methylprednisolone(MP) can significantly improve recovery. Significant advances in recent year, including an effective drug therapy for acute SCI, have improve recovery. In spinal cord injury, pain persist for longer period i.e., several months, hence the long-term treatment is necessary for maintaining the drug concentration in the therapeutic range.

Hence, there is a need of sustained release dosage form. Baclofen,4-amino-3-(4-chlorophenyl)-butyric acid is another structural analog of GABA, which is widely used now a days in the treatment of multiple sclerosis, flexor spasms, muscular rigidity. spinal cord injuries and other spinal cord diseases.

POLYELECTROLYTES: AS A DRUG DELIVERY SYSTEM

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ABOUT AUTHORS:
Surya Pratap Singh*, Meenakshi Sahetya1, Mahaveer Prasad khichi1*, Yogesh Yaduwanshi2
1Department of pharmaceutics, Kota college of pharmacy
2Department of pharmacology, Kota college of pharmacy,
Rajasthan, India
*sp.kota91@gmail.com

ABSTRACT
The purpose of this paper is to focus on drug delivery system developing by such polyelectrolytes and most focused on targeting of  drugs to specific sites have aroused as revolution in pharmaceutical  field, thereby, giving rise to drug  delivery systems. Polymers have gained much importance indrug delivery especially those which respond in some desired way to change in pH, temperature, electric or magnetic field. For this reason they are very frequently and extensively used as excipients in design and advancement of controlled and/or sustained release products. The scope of polymers used in dosage form design can be increased by several approaches such as modification of their chemical structure, by combining different polymers in physical mixtures or by formation of polymer-polymer associations such as polyelectrolyte complexes.

AICTE Sponsored National Seminar on Current and Recent Advancement in Targeted Drug Delivery System (Sunday & Monday) February 9th & 10th, 2014 at Kota College of Pharmacy

Kota College of Pharmacy Kota, affiliated to Rajasthan University of Health Sciences. Jaipur is approved by All India Council of Technical Education, New Delhi, Pharmacy Council of India, New Delhi and Government of Rajasthan. Established in 2004, the college offers undergraduate course in Pharmaceutical Sciences and Post Graduate courses in Pharmaceutics and Pharmacology. KCP has strong research foundation with AICTE funded Research Projects, Entrepreneur Development Cell (EDC1 and DST Projects by Govt, of Rajasthan. Five batches of BPharm. and one batch of M.Pharm. have already passed from the college. The college provide most effective teaching learning environment using latest teaching aid and equipments. The college is approved centre for guiding research in the area of Pharmaceutical Science.

A REVIEW ON NEUROTOXICITY

About Authors:
Yogesh Yaduwanshi*, Gireesh Mehta, Jitendra Shakyawal, Surya Pratap, Sanjay Singh, Mahaveer Kabra
Department of Pharmacology,
Kota College of Pharmacy, Kota,
Rajasthan India
*yogeshyaduwanshi24@gmail.com

Abstract:
Chemicals are an integral part of our daily lives and are responsible for substantially improving them. Yet chemicals can also endanger our health, even our survival. This report focuses on neurotoxic substances, those chemicals that adversely affect the nervous system. Included among such substances are industrial chemicals, pesticides, therapeutic drugs, abused drugs, foods, food additives, cosmetic ingredients, and naturally occurring substances. Whether a substance causes an adverse health effect depends on many factors, including the toxicity of the substance, the extent of exposure, and an individual's age and state of health. Minimizing public health risks requires knowledge about the properties and mechanisms of action of potentially toxic substances to which humans may be exposed. The assessment includes discussion of industrial chemicals, pesticides, therapeutic drugs, substance drugs, foods, food additives, cosmetic ingredients, and such naturally occurring substances as lead and mercury. It does not include radioactive chemicals, nicotine, alcohol, biological and chemical warfare agents, microbial, plant, and animal toxins, and physical agents such as noise.

CLINICAL RESEARCH: TRIALS & SCOPE

About Author:
Mr. Piyush Tripathi
Kota College of Pharmacy
Kota, Rajasthan.
piyushtripathi1992@rediffmail.com

Introduction:
The term Clinical Research refers to the entire bibliography of a drug from its inception in the lab to its introduction to the consumer market & beyond. Not every compound that is tested in the lab is marketed. Before a drug is marketed, it has to undergo several stages of development.

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