Guwahati

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ABOUT AUTHORS
T. Raja Sekharan¹*, Shunmugaperumal Tamilvanan², S. Rajadurai¹, S. Mohammed Ibrahim¹ and K. Kavipriya
¹ Sankaralingam Bhuvaneswari College of Pharmacy, Anaikuttam-626130, Sivakasi, Tamil Nadu, India.
²National Institute of Pharmaceutical Education and Research (NIPER)‑Guwahati, C/O NETES Institute of Technology and Science, NH‑37, Shantipur, Parli Part, Mirza, Assam 781125, India

ABSTRACT
The main objective of this study was to formulate an Ibuprofen loaded emulsion from the eutectic mixture and Eudragit RL 100. The eutectic mixture was formed with camphor and menthol which was approved by the FDA. A eutectic mixture is defined as a combination of two or more components at a certain ratio intermingle to form a new chemical compound resulting in a system having a lower melting point than either of the components. The formulated emulsion from the eutectic mixture was evaluated for various studies like pH checking, stability checking by centrifugation, viscosity, particle size analysis, quantitative drug analysis, thermodegradation and in-vitro drug release studies. Neutral pH values resulted in the formulations. The formulation was stable even after it was centrifuged for 5000 rpm for 30 min. Viscosity results showed the formulation was less viscous results in good spreadability. Particle size was determined with particle size analyzer. Drug analysis results revealed about 96 % of drugs are incorporated into the formulation. Thermodegradation results proved that there was no spillage of drugs from the formulations even when the drug was stored at different temperatures. In-vitro drug release study was performed by varying drug concentrations. The results showed there was no change in the drug release even after varying the drug concentration. From the results it was concluded that Ibuprofen was successfully formulated as an emulsion with the help of eutectic mixture a Eudragit RL 100.

National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an 'Institute of National Importance'. It is an autonomous body set up under the aegis of Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of India. The Institute is conceived to provide leadership in pharmaceutical sciences and related areas not only within the country, but also to the countries in South East Asia, South Asia and Africa. NIPER is a member of Association of Indian Universities and Association of Commonwealth Universities.

National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an 'Institute of National Importance'. It is an autonomous body set up under the aegis of Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of India. The Institute is conceived to provide leadership in pharmaceutical sciences and related areas not only within the country, but also to the countries in South East Asia, South Asia and Africa. NIPER is a member of Association of Indian Universities and Association of Commonwealth Universities.

National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an 'Institute of National Importance'. It is an autonomous body set up under the aegis of Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of India. The Institute is conceived to provide leadership in pharmaceutical sciences and related areas not only within the country, but also to the countries in South East Asia, South Asia and Africa. NIPER is a member of Association of Indian Universities and Association of Commonwealth Universities.

Johnson & Johnson was founded more than 120 years ago on a revolutionary idea: Doctors and nurses should use sterile sutures, dressings and bandages to treat peoples’ wounds.  Johnson & Johnson is ranked by Fortune Magazine as the 3rd most Admired Pharmaceutical Company in the world with an outstanding product range as well as an extensive research base with a number of life saving original research molecules.

Indian Institute of Technology the sixth member of the IIT fraternity, was established in 1994. The academic programme of IIT Guwahati commenced in 1995. At present the Institute has eleven departments and three inter-disciplinary academic centres covering all the major engineering, science and humanities disciplines, offering BTech, BDes, MA, MDes, MTech, MSc and PhD programmes.

Post : JRF (GATE)

Indian Institute of Technology the sixth member of the IIT fraternity, was established in 1994. The academic programme of IIT Guwahati commenced in 1995. At present the Institute has eleven departments and three inter-disciplinary academic centres covering all the major engineering, science and humanities disciplines, offering BTech, BDes, MA, MDes, MTech, MSc and PhD programmes.

Assam down town University (AdtU) is one of the North Eastern leading university offering its students a unique amalgamation of professional and academic excellence. AdtU has coupled the experience of top industry leaders and renowned academicians and fosters a worldly approach. AdtU the largest educational group based in Assam, has on its rolls 4000+ students and more than 300+ faculty members. The State-of-the-art campus in Guwahati located on 80 acres of land.

State Bank of India (SBI) Group is the biggest financial services conglomerate in India. Headquartered in Mumbai, SBI provides a wide range of products and services to individuals, commercial enterprises, large corporates, public bodies and institutional customers through its various branches and outlets, joint ventures, subsidiaries and associate companies. The Group comprises of State Bank of India (SBI), its various non-banking subsidiaries/ joint ventures, and foreign banking subsidiaries/ joint ventures.  SBI, the flagship company of the group, traces its ancestry to Bank of Calcutta founded in 1806. It was the first bank established in India, and over a period of time, evolved into State Bank of India (SBI). SBI represents a sterling legacy of over 200 years. It is the oldest commercial bank in the Indian subcontinent, strengthening the nation’s trillion-dollar economy and serving the aspirations of its vast population.

Post : Pharmacist