Maharashtra

About Authors:
Mr.Sanjay wasudeo upare^*, Dr.A.V.Chandewar, Dr.M.D.Kshirsagar, Mr.U.S.Koli and Mr.H.K.Pokale
M-Pharm IV semester (Pharmaceutics department)
Pataldhamal Wadhwani college of Pharmacy,
Yavatmal
*uparesanju81@gmail.com

ABSTRACT:
Lornoxicam is a non steroidal anti-inflammatory drug with analgesic properties. The purpose of this study was to develop a taste masked oral disintegrating tablet of poorly soluble Lornoxicam by direct compression technique with β-cyclodextrin (BCD) complexes using various super disintegrants like sodium starch glycolate, crospovidone and L-Hpc. Prepared tablets were evaluated for different properties like drug content, hardness, friability, disintegration time and in vitro dissolution study. The different formulations showed disintegration time between 21 to 33.66 s. Drug release showed time between the ranges of 5 to 30 min. Among all the formulations, L1 showed 97.79% drug release within 30 min. Thus, L1 was considered best among the other formulations.. The tablets showed enhanced dissolution hence better patient compliance.

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Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.

Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia.

About Author:
NITESH.P.SHARMA, AJAY.GUPTA
IDEAL COLLEGE OF PHARMACY AND RESEARCH, KALYAN
MUMBAI UNIVERSITY
Sharmanitesh479@yahoo.com

ABSTRACT:
The antibacterial activity of essential oils and their derivatives has been recognized for a long time. In the present study, the antibacterial properties of the essential oils obtained from the seeds of Seseli indicum, of Apiaceae family a wild weed found in the flood prone area of river Tapti, Gorakhpur (India). The essential oil obtained from seed was 3.4%. Essential oils were investigated for activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis using a punched-hole method. Essential oils inhibited all bacteria at both, low and high concentration. The results of this study confirmed the possibility of using Seseli indicum essential oils in broad spectrum antibacterial activities.

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