Maharashtra

Mazagon Dock Limited is the India’s premier shipyard constructing warships as well as offshore platforms.

Saraswathi Vidya Bhavan’s College of Pharmacy is affiliated to the University of Mumbai and Approved by All India Council for Technical Education (AICTE). The College offering Bachelor of Pharmacy and Bachelor of Pharmacy course.

APPLICATIONS ARE INVITED FOR THE FOLLOWING FULL TIME POSTS FOR ACADEMIC YEAR 2012-13.

RASA is a Bio & Chemo Informatics company offering solutions and services in the area of Life sciences. We are looking for young talented students who are willing to grow with us. We entertain only freshers because we feel that it is easier to train them in the specific fields rather than training experienced professionals.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia.

Marion Biotech strongly believes in an integrated approach to healthcare. It is also engaged in extensive Research & Development of unique Herbal products. At Marion Biotech, we set Stringent Standards of Quality, Safety and Efficacy for all the Products that we manufacture.

Leading pharma company located in Mumbai; Manufacturing of Sustained & modified release, Pellets, DC granules, Taste mask Granules, Tablets & Capsules.

About Authors:
Borse V. G.*, Birajdar A. S., Datal A. A.
K. T. Patil College of Pharmacy,
Osmanabad-413501, Maharashtra, India.
*vishalgborse@gmail.com

ABSTRACT :
The objective of this study is to enhance dissolution rate of practically insoluble drug olanzapine, using surface solid dispersion technique. Olanzapine is classified as a thiobenzodiazepine atypical antipsychotic drug used in the treatment of schizophrenia. Surface solid dispersion technique is used to prepare solid dispersion of olanzapine using Crospovidone as carrier. Surface solid dispersion were characterised by saturation solubility studies, drug content and in- vitro dissolution studies. Solubility studies revealed a marked increase in the solubility of olanzapine with an increase in Crospovidone concentration. The best dispersion was selected based on saturation study and release study and evaluated for solid state characterization techniques Differential scanning calorimetry, FT-IR spectroscopy study. The results from DSC and IR indicated that there was no interaction between drug and carriers. Surface solid dispersion of olanzapine shows increase in aqueous solubility 4.42 fold than pure drug. SSD with Crospovidone in 1:9 ratio give highest drug release i.e. 88.87%.Surface solid dispersion is successful technique to improved drug dissolution of olanzapine with the carrier Crospovidone.

It is proposed to engage full time Para Medical staff for the following posts purely on contract basis on BCT Division of Western Railway. The details of the post, place of posting, remuneration etc. and other terms and conditions stipulated are given below:-

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia.