Maharashtra

Our client is highly reputed client since a decade and having a multiple branch in Foreign as well as in INDIA.

Post: Clinical Research Associate

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ABOUT AUTHORS:
Kharat Rekha¹*, Jadhav Santosh¹, Pawar Seemarani², Tamboli Ashpak^2
1Department of Pharmaceutics, Sahyadri College of Pharmacy, Methwade,
Sangola, Solapur, Maharashtra, India
²Department of Pharmaceutical chemistry, Sahyadri College of Pharmacy, Methwade,
Sangola, Solapur, Maharashtra, India
*kharatrs26@gmail.com

ABSTRACT:
A simple, precise and accurate difference spectroscopic method has been developed for the estimation of Ciprofloxacin Hydrochloride in bulk drug form by difference spectrophotometric method. Ciprofloxacin Hydrochloride has exhibited maximum absorbance at about 272nm and 278nm in acidic and basic solution respectively. Beer’s law was obeyed in the concentration range of 2-10 µg/ml in both the cases. The regression of coefficient was found to be r²=0.9982. The LOD and LOQ value were found to be 0.5140ppm and 0.5577ppm respectively. The proposed method was successfully applied for the determination of Ciprofloxacin Hydrochloride in bulk drug. As per ICH guidelines the result of the analysis were validated statistically and were found to be satisfactory.

We are hiring for our well reputed pharma client

Post: Executive / Sr. Executive / Asst. Manager-SAP IT (Mumbai & Mahad)

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No.of post: 3 Nos.

MSACS envisions an India where every person living with HIV has access to quality care and is treated with dignity. Effective prevention, care and support for HIV/AIDS is possible in an environment where human rights are respected and where those infected or affected by HIV/AIDS live a life without stigma and discrimination.

Post: Pharmacist- (ART Center, Civil Hospital Nandurbar & for WL)

The Institute of Chemical Technology (ICT) Mumbai was established as the Department of Chemical Technology on 1st October, 1933 by the University of Mumbai, through active support of industries and philanthropists. The Institute was most popularly known as UDCT, Mumbai. Research has been an integral part of ICT since its inception and it has created over 500 first generation entrepreneurs. The UDCT grew significantly in stature and was granted autonomy under UGC regulations by the University of Mumbai and further converted in to an Institute on 26th January, 2002. Under the World Bank TEQIP programme, the Maharashtra government granted it full autonomy in June 2004. Due to the recommendations of the Government of Maharashtra and University of Mumbai, the ICT was granted Deemed University Status by the MHRD on 12th September, 2008, with all provisions of the UGC for funding and support as the state owned deemed university.

Post: Research Fellow

Post: Pharmacist

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No.of post: 01

Qualification: Passed have D.Pharm

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ABOUT AUTHORS:
Sagar Alone*, Sharda Deore, Bhushan Bawiskar
Department of Pharmacognosy & Phytochemistry
Govt. College of pharmacy, Kathora naka, Amravati-444604, India
*sagaralone123@gmail.com

ABSTRACT
Total seventeen saponins previously isolated from roots of Pulsatilla koreana having cytotoxic activity against 4 different cancer cell line (A-549, SK-OV-3, SK-MEL-2, HCT15) were used for 2D QSAR using V-life Molecular design suit. Using multiple linear regression method against 4 different cell lines develops QSAR model. QSAR model was generated by using training set of 11 and test set of 6 molecules having correlation coefficient (r²), significant cross validated correlation coefficient (q²) and F-test (For statistical significance) is as given below  (A-549: r²- 0.9281, q²- 0.8691, F-test- 51.6079),  (SK-OV-3: r²- 0.9554, q²- 0.9184, F-test- 85.7357),  (SK-MEL-2: r²- 0.9160, q²- 0.8285, F-test- 43.6084),  (HCT15: r²- 0.9203, q²- 0.8357, F-test- 46.1887). In this QSAR study Alignment independent descriptors such as T_2_C_7, T_O_O_5 and physicochemical descriptors like Chain path count such as 6 chain count and Chi chain such as Chi 6 chain were most responsible descriptors for anticancer activity.