• PharmaTutor
    26 March 2012

    A REVIEW ON FORMULATION AND EVALUATION ASPECTS OF ENTERIC COATED PELLETS

    About Authors:
    Kapil Sharma*, Priyanka Sharma**
    *M.Pharm, Yaresun Pharmaceutical Pvt Ltd, India
    **M.Sc, Yaresun Pharmaceutical Pvt Ltd,
    Rajasthan, India.

    1.PELLETS
    Pellets are spheres of varying diameter depending on the application and the wish of the producer. Applications are found not only in the pharmaceutical industry but also in the agribusiness (e.g., fertilizer, fish food) and in the polymer industry.
    In the pharmaceutical industry, Pellets can be defined as small, free-flowing, spherical particulates manufactured by the agglomeration of fine powders or granules of drug substances and excipients using appropriate processing equipment. The term also has been used to describe small rods with aspect ratios of close to unity.

  • 23 March 2012
    A REVIEW ARTICLE ON RESEARCH & DEVELOPMENT OF PHARMACEUTICAL MEDICINE WITH SPECIAL EMPHASIS ON PREFORMULATION (A NEED FOR DOSAGE FORM DESIGN)

    About Authors:
    Kapil Sharma*, Priyanka Sharma**
    *M.Pharm, Yaresun Pharmaceutical Pvt Ltd, India
    **M.sc, Yaresun Pharmaceutical Pvt Ltd,
    Rajasthan, India.

    Aim: - To search Pharmaceutical medicine (New, Safe & Effective) to enhance health and benefits of patients & community.

    Trends:-Usually search a pharmaceutical medicine is starting from “Drug Discovery and Drug Development” (D4) or Pharmaceutical R&D.
    D4 is very long, very costly and very complex process, so mostly companies put together D4 plan. Drug Discovery and Drug Development is the treds of searching a Pharmaceutical medicine

  • 21 March 2012
    Opening in an autonomous institute of Government of India -THSTI for PG in Pharmacy & Lifesciences as SRF & JRF | Total 9 Posts

  • 21 March 2012
    Walk in interview for post of SRF in National Institute for Research in Reproductive Health

    National Institute for Research in Reproductive Health (NIRRH), formerly known as Institute for Research in Reproduction is a premier research institute of the Indian Council of Medical Research (ICMR). It is situated in the vicinity of a number of hospitals and research institutes in central Mumbai. Since its inception in 1970, it has been making vigorous efforts to improve the reproductive health of people through research, education and health care services.

  • 20 March 2012
    Walk in Interview in Indian Institute of Technology for position of Jr. Research Fellow

    Indian Institute of Technology Roorkee, Roorkee invites the applications on the prescribed form for the following posts as per details given against each. The application form and general conditions may be obtained from Superintendent, Establishment ‘B’ Section, IIT Roorkee.

  • 18 March 2012
    Require Fresh & Exp. B.Pharm and M.Sc, Ph.D, MBBS, MVSc as Scientists in B to H at NATIONAL INSTITUTE OF ANIMAL BIOTECHNOLOGY (NIAB), Government of India | Total 12 posts

  • 18 March 2012
    Work in J. Mitra Pharma | AM-HR, Trainee QA Officer, QA Executive, Research Associate, Manager Customer Service, ASM, Product Executive, Asst. Manager- QA

    J.Mitra is mainly involved in the business of preserving Human life of critically unwell people. We aim At taking the utmost care of our clients as well as our employees. GROUP focus is on creativity, fresh ideas backed by empowerment, delegation and calculated risk taking. Our Endeavour is to create an environment where talent can reach to its peak & to do so we strive to make the workplace a source of creativity & innovation.

  • 18 March 2012
    VALIDATED RP – HPLC METHOD FOR DETERMINATION OF MONTELUKAST SODIUM AND LEVOCETIRIZINE IN BULK AND ITS PHARMACEUTICAL FORMULATIONS USING UV-VIS DETECTOR

    About Authors:
    RAVISANKAR.M*1, SUBASINI.U2, ANAND THANGADHURAI.S3, KARTHIKEYAN.S4, CHANDRA SEKAR.E.5
    1.Swamy Vivekanandha College of pharmacy, dept of pharmaceutical analysis. Thiruchengode
    2.Swamy Vivekanandha College of pharmacy, dept of pharmacognosy. Thiruchengode
    3.Swamy Vivekanandha College of pharmacy, dept of pharmaceutical analysis. Thiruchengode
    4.Kausikh therapeutics and private limited.chennai
    5.Swamy Vivekanandha College of pharmacy, dept of pharmaceutical analysis. Thiruchengode

    ABSTRACT
    An isocratic reverse phase high performance liquid chromatographic method for estimation of montelukast sodium and levocetirizine in bulk dosage and in marketed formulations has been devised and validated. The chromatographic separation achieved on shodex c18-4E column (5µm, 250 mm x 4.6 mm) and  acetonitrile: methanol: ammonium acetate buffer (PH- 5.5) in the ratio of 25:55:20 v/v. The flow rate was 1.0 ml/min and the UV detection was identified at 225nm.The retention times for montelukast sodium and levocetirizine was found to be 5.15 min and 3.12 min respectively. The linearity of montelukast sodium and levocetirizine is 10 -50µg/ml with the correlation co efficient 0.99 respectively. The validation parameters such as accuracy, precision, LOD, LOQ, Robustness, ruggedness were performed as per ICH guidelines. This method can be used for routine analysis of montelukast sodium and levocetirizine in bulk and marketed dosage forms.

  • 16 March 2012
    Require Primary Research Associate in Forrester Research

    Forrester Research, Inc. (Nasdaq: FORR) is an independent research company that provides pragmatic and forward-thinking advice to global leaders in business and technology. Forrester works with professionals in 19 key roles at major companies providing proprietary research, customer insight, consulting, events, and peer-to-peer executive programs. For more than 28 years, Forrester has been making IT, marketing, and technology industry leaders successful every day.

  • 14 March 2012
    VALIDATED UV-SPECTROPHOTOMETRIC AND RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF PARACETAMOL AND CHLORZOXAZONE IN TABLET DOSAGE FORM

    About Authors:
    Manoj Kumar Jadia1*, U.L.Narayan2
    1 Department of Pharmaceutical Chemistry, Indira Gandhi Institute of Pharmaceautical Sciences, I.R.C. Village, Bhubaneswar, Dist:Khurda, Odhisa -751015
    2 Principal, Department of Pharmaceutical Chemistry, Indira Gandhi Institute of Pharmaceautical Sciences, I.R.C. Village,
    Bhubaneswar,
    Dist:Khurda, Odhisa -751015

    Abstract:
    Two methods are described for the simultaneous determination of Paracetamol and Chlorzoxazone in binary mixture. The first method was based on UV-spectrophotometric determination of two drugs, using simultaneous equation method. It involves absorbance measurement at 282.5 nm (λmax of Chlorzoxazone) and 248.0 nm (λmax of Paracetamol) in methanol; linearity was obtained in the range of 5 – 25 μg.mL-1 for both the drugs. The second method was based on HPLC separation of the two drugs in reverse phase mode using Promosil C18 column. Linearity was obtained in the concentration range of 100-500 μg.mL-1 for Paracetamol and 50-250 for  the Chlorzoxazone. Both these methods have been successively applied to pharmaceutical formulation and were validated according to ICH guidelines.

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