Pharma News

Burning issue - Present status of Pharmaceutical Industries

“Recent acquisition of Indian generic drug companies by MNCs has increased fears that the price of low-cost generic drugs will rise in India. The buy-outs will reduce domestic availability of many essential medicines; point out an internal assessment of the health ministry, Government of India. It is ironic that despite India supplying quality generic drugs around the world, the country has concerns about sufficient domestic drug supply and vaccines security. With the increasing acquisition of Indian companies by overseas drug corporations, there is a pressing need to rethink India’s drug strategy”. This statement was released by government of India before few months. Now what global honchos think about India?

View - There is no hope for the perfect research work

Research is an important tool for the human society. It is used to demystify the unsolved enigma of the nature. Homo sapiens are the most intelligent creature who has ever dominated the earth by his Intellectual reasoning and capacity. As we are living in 21st century which is known as modern age. So it is vital to do research to discard the age-old hypothesis and to establish clear/concise conceptions about a particular issue which can makes our lives safer in the planet.


About Authors:
S Hamza*1, Dr Tanveer Aalam2, Dr Asma3
Assistant Professor, Department of Pharmacology,
Shree M V Shah Pharmacy college,
Gajan, Modasa: 383315, Gujarat.
2 Department of Emergency Medicine,
Apollo hospitals International Ltd,
Bhat GIDC estate,  Gandhinagar: 382428, Gujarat.
3 Medical Officer, Civil Hospital,
Ahmadabad: 380 002. Gujarat, India

India suffers from the highest number of deaths - around 1,05,000 in absolute terms annually- due to road accidents in the world owing to poor infrastructure and dangerous driving habits according to the World Health Organisation1. Calling road fatalities an "epidemic" that will become the world's fifth biggest killer by 20302. It is said that 90% of deaths on the world's roads occur in low and middle-income countries (21.5 and 19.5 per lakh of population, respectively) though they have just 48% of all registered vehicles.


1Institute of Pharmaceutical Sciences,
Kurukshetra University, Kurukshetra 136119, Haryana, India.
2Department of Pharmaceutical Sciences,
MDU, Rohtak 124001,
Haryana, India.

The aim of the present study was to investigate the in-vitro release properties of Ziprasidone hydrochloride monohydrate from different topical vehicles. By the unique advantages over the traditional drug delivery, transdermal drug delivery is becoming increasingly important and has got a vital interest in pharmaceutical industries. An in vitro release experiment was designed to reveal the rate of release of ziprasidone hydrochloride monohydrate from four different topical vehicles: (i) cream; (ii) a gel; (iii) an ointment (iv) pronoisomal gel. In vitro release of ziprasidone hydrochloride monohydrate from the four bases was monitored spectrophotometrically at a wavelength of 318 nm. In vitro release study results showed that the release of drug from vehicles ranks according to the following order: gel> proniosomal gel> cream> ointment. Gel base showed considerably higher drug release than other vehicles. Five types of chemical enhancers was used in the study and among them tulsi oil was the best enhancer. As we increase the concentration of chemical enhancer the release of drug also increases. By monitoring and attempting to explain the many possible reasons for the different rates of drug release from the vehicles, it was hope that the experiment would confer essential information concerning factors affecting the release of drugs from topical formulations.

Stevia rebaudiana : a ray of life for diabetics

Stevia rebaudianais a well known medicinal herb contains antibacterial, antifungal, anti-inflammatory, anti-viral, anti-yeast, cardiotonic diuretic and hypoglycaemic properties. This herb has been used in Ayurveda in India since centuries. Stevia is a perennial herb belonging to the family Asteraceae, is one of the most valuable tropical medicinal plant. Leaves of this plant produce zero calorie, high potency sweetener and substitute to sucrose, being about 300 times sweeter than sucrose. The compounds, named stevioside and rebaudiocide give stevia its taste. In India number of diabetic people in the age group of 25-45 is about 15% and is also increasing at an alarming pace. In addition, India is the largest consumer of sugar in the world. So stevia is attaining attention in Indian market as a healthy alternative sweetener to sugar. Stevia has no calcium cyclamate, no saccharim, no aspartame and no calories. It is safe for diabetics, as it does not affect blood sugar levels and have no neurological or renal side effects.


About Author:
Tarun Patel, Prof. Dr. Vipin Kukkar, Amit Patel

Seth G.L. Bihani S.D. College of Technical Education,
Institute of Pharmaceutical Sciences and Drug Research,
Sri Ganganagar, Rajasthan, INDIA

It is a product which is used for improvement of appearance of human body by applying it externally on human body. For better results and minimizing risk of adverse reaction of cosmetic products on human body we have to check out and maintain quality of cosmetic products during its manufacturing.  And  also required some safety parameters for manufacturing of cosmetic products. In this review article we discussed briefly about quality and safety parameters during manufacturing of cosmetic products.


About Authors:
Sreedhar Reddy C
M.Pharm, Department of Pharmaceutics,
Vasavi Insitute of Pharmaceutical Sciences,
Vasavi Nagar, Peddapalli (V), Kadapa (dist),
A.P, India

In this study, transdermal patches containing Itraconazole were prepared using different ratios of polyvinylpyrrolidone (PVP) and Hydroxy propyl methyl cellulose (HPMC) by solvent evaporation technique using 10%w/w of dibutyl phthalate incorporated as plasticizer. The drug matrix film of PVP and HPMC was casted on a polyvinylalcohol backing membrane that was previously dried at 600C for 6 hrs. All the prepared formulations were subjected to physical studies (moisture content, moisture uptake, Tensile strength, flatness and Drug content determination), in vitro release studies and in vitro skin permeation studies. The physiochemical compatibility of the drug and the polymers studied by IR spectroscopy have absence of any incompatibility. In vitro permeation studies were performed across  skin using a Franz diffusion cell. Variations in drug release profiles among the formulations studied were observed. Based on a physicochemical and in vitro skin permeation study, formulation F1 (PVP/HPMC, 5:1) and F5 (PVP/HPMC, 1:5) were chosen for further in vivo experiments. The anti inflammatory effect and a sustaining action of Itraconazole from the two transdermal patches selected were studied by inducing paw edema in rats with 1% w/v carrageenan solution. Hence, it can be reasonably concluded that Itraconazole can be formulated into the transdermal matrix type patches to sustain its release characteristics.

Corporate Environmental Responsibility of Indian Pharma Companies

The Indian Pharmaceutical Industry today is in the front rank of India’s science-based industries with wide ranging capabilities in the complex field of drug manufacture and technology. It ranks very high in the third world, in terms of technology, quality and range of medicines manufactured. From simple headache pills to sophisticated antibiotics and complex cardiac compounds, almost every type of medicine is now made indigenously.

Naming of Drug Molecules and Pharmaceutical Brands

About Authors:
Dr. Amit Gangwal,
Smriti College of Pharmaceutical Education,

For running any business or organization their products or services should be of utmost quality keeping other things aside. These products or services are known in commerce by their names. These names are called brand names and these are assigned by the owner or innovator or researcher or sponsor of that product or service depending on the type of produce and various parameters. Though company introduces the brand in commerce but after its (brand’s) establishment, brand becomes the identity of company. Brand names are most important attribute of a product after its quality and packing from end user’s (customer) point of view. Successful brand names never escape from the memory of consumer. Few such brand names are Bislery, Maggi, Vicks, Surf Excel, Coca-Cola, Google etc. Few reputed and well known pharmaceutical brands are Corex, Lipitor, Gleevac, Viagra etc. In present article various process to name a drug and a pharmaceutical formulations’ name (brand name) have been described. Article throws light on generic, chemical and brand names of a drug or formulations besides few case studies and guidelines.