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  • A POTENT TARGET FOR CANCER TREATMENT – TUMOR HYPOXIA NECROSIS: AN OVERVIEW

  • PROJECT SCIENTIFIC OFFICER require in Tata Institute of Fundamental Research
    PROJECT SCIENTIFIC OFFICER require in Tata Institute of Fundamental Research

    "It is the duty of people like us to stay in our own country and build up outstanding schools of research such as some other countries are fortunate to possess." This was the vision that guided the Tata Institute of Fundamental Research which Homi Bhabha founded. The Institute was founded on 1st June1945 with support from the Sir Dorabji Tata Trust.

  • BRAIN AS A SANCTURIAN SITE IN DRUG DELIVERY APPROACHES TO IMPROVE BIOAVAILABILITY IN BRAIN
    BRAIN AS A SANCTURIAN SITE IN DRUG DELIVERY APPROACHES TO IMPROVE BIOAVAILABILITY IN BRAIN

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    ABOUT AUTHOR
    Sagar Vishwanath Sonawane*
    Dept. of Pharmaceutical Sciences and Technology,
    Institute of Chemical Technology,
    Matunga, Mumbai, Maharashtra, India.
    *sssagarvs@gmail.com

    ABSTRACT
    Brain is the highly protected organ of the body by the sanctuary known as blood brain barrier (BBB). BBB comprises of tight junctions formed by the closed fenestration network of astrocytes, pericytes microglial cells and endothelial cells. Thus it is very difficult for drug molecules to cross BBB. Thus various approaches are discussed to overcome this barrier. Disruption of BBB was conventional invasive approach. The permeability of BBB increases in various diseases. This increased permeability of BBB is made use for drug trafficking. With advances in nanotechnology, various nanocarrier systems including Polymeric nanoparticles, Micelle, Dendrimer, Liposomes, Solid lipid nanoparticles, Nanostuctured lipid carriers, nanogels, etc. emerged as potential delivery systems.
    Administration of inhibitors of p-glycoprotein with drug is another approach. Making lipophilic prodrugs of active drug substances can also be done.
    Recently PEGylation of nanoparticles can be done to improve its half life in the body, known as the stealth technology. Further various receptor mediated processes are made use of for transport of nanocarrier across BBB. In this method the nanocarrier is attached to the targeting ligand thus making it receptor specific. The newer concept of molecular Trojan horses is also discussed. Finally the advantages of intranasal drug delivery are emphasized.

  • Aspiring Solutions hiring Medical Doctor/Writer for its Online Pharmacy Client
    Aspiring Solutions hiring Medical Doctor/Writer for its Online Pharmacy Client

    Aspiring Solutions hiring for its Online Pharmacy Client; Our client is hiring for its sister concern online pharmacy holding potential international markets and patients worldwide

    Post: Medical Doctor/Writer (1 opening)

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  • Career for Master of Pharmacy or Ph.D as Medical writer in Nexuscro
    Career for Master of Pharmacy or Ph.D as Medical writer in Nexuscro

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    Job Description: Protocol writing
    Clinical study report
    Case Report Form

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    Required for Area Business Manager in RPG Life Sciences

    RPG Life Sciences, a part of the Rs. 18,000 crore RPG Enterprises, is an integrated pharmaceutical company operating in the domestic and international markets in the Branded Formulations, Global Generics, Synthetic and Fermentation APIs space. The company is a research based, pharmaceutical company, producing a wide range of quality, affordable medicines. Its brands are highly trusted by healthcare professionals and patients. Customer satisfaction is fundamental to the company.

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    Vacancy for MSc in any branch of life sciences as Senior Technical Specialist in ACTREC

    The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC, Kharghar, Navi Mumbai is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer. TMC is an autonomous grant-in-aid institution of the Department of Atomic Energy (DAE), Government of India. It is registered under the Societies Registration Act (1860) and the Bombay Public Trust Act (1950). Its Governing Council is headed by the Chairman, Atomic Energy Commission, Government of India.

    Post: Senior Technical Specialist 1 Post

  • Neon Laboratories requires B.Pharm, B.Sc as ZSM/RSM, ASM, FSO
    Neon Laboratories requires B.Pharm, B.Sc as ZSM/RSM, ASM, FSO

    Neon Laboratories Limited is the fastest growing Generics Segment Pharma Company. We need suitable candidates at various locations in U.P., Uttaranchal, Delhi, Haryana, Rajasthan, West Bengal, Andhra Pradesh Jamilnadu, Kerala, Gujrat & Karnataka.

    Post: ZSM/RSM, ASM, FSO

  • Project of International Cancer Genome Consortium (ICGC) - India Project for the post of Research Associate in ACTREC
    Project of International Cancer Genome Consortium (ICGC) - India Project for the post of Research Associate in ACTREC

    The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC, Kharghar, Navi Mumbai is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer. TMC is an autonomous grant-in-aid institution of the Department of Atomic Energy (DAE), Government of India. It is registered under the Societies Registration Act (1860) and the Bombay Public Trust Act (1950). Its Governing Council is headed by the Chairman, Atomic Energy Commission, Government of India.

    Post: Research Associate- 1

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    Marc Laboratories Limited is the fastest growing Multidivisional Pharma Company. Under our expansion plan in Cardiac, Diabetic, Neuro & Pharma Divisions. We need suitable candidates at various locations in U.P., Uttaranchal, Delhi, Haryana, Rajasthan, West Bengal, Andhra Pradesh Jamilnadu, Kerala, Gujrat & Karnataka.

    Post: ZSM/RSM, ASM, FSO

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