Hyderabad

MakroCare Expert Strategic Development and Commercialization Global Partner for Pharmaceutical, Biotechnology and Medical Device industries. Our Experience, Programs and Processes bring a New Dimension to Development Strategy, Regulatory/Risk Planning & Management, Clinical Research, Medical/Scientific Support and Emerging Region Expansion

Post : Bio-Statistician - 05 posts

MakroCare Expert Strategic Development and Commercialization Global Partner for Pharmaceutical, Biotechnology and Medical Device industries. Our Experience, Programs and Processes bring a New Dimension to Development Strategy, Regulatory/Risk Planning & Management, Clinical Research, Medical/Scientific Support and Emerging Region Expansion

Post : Senior SAS Programmer - 02 posts

MakroTech is a leading global consulting and technology services company, offering a wide array of solutions customized for a range of key verticals and horizontals. From strategy consulting right through to implementing IT solutions for customers, Makro straddles the entire IT space. It has excellent domain competencies in verticals such as Healthcare, Pharmaceutical, Financial, Telecom, IT, Government and other industries. As a diverse end-to-end IT solutions provider, Makro offers a range of expertise aimed at helping customers re-engineer and re-invent their businesses to compete successfully in an ever-changing marketplace.

Post: Junior Medical Writer(05 posts)

[adsense:336x280:8701650588]

MakroCare has operations and presence in US, UK, EU, and Asia. MakroCare is well positioned to meet the demands of the expanding product portfolio needs of our life sciences clients worldwide. We also understand the demands of an increasingly competitive market.

Post : Sr.CDA (02 posts)

The Dr. Reddy's Institute of Life Sciences was conceived in the context of globalization, to foster research competence in India and to bridge the divide between academic research and the pharmaceutical & biotechnology industries.  The institute was incorporated as a non-profit entity under Section 25 of the Indian companies act, facilitating operational autonomy. Construction of the DRILS building comprising 44 labs and an administrative block and spanning ~130,000 sq.ft. in area, began in 2004 and was completed in January 2007.

POSITION: Junior Research Fellow (JRF)

National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad is a prestigious educational institution of National importance, established in the year 2007 under the aegis of Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, Govt, of India. NIPER, Hyderabad conducts courses in MS (Pharm.), M.Tech (Pharm.) in Pharmaceutical Sciences and MBA (Pharm.) in Pharma Management for Two years. Students are selected through a National Entrance Test (JEE). Research opportunities also exist for those who would like to pursue their Doctoral Degree, The Institute is mentored by CSIR-Indian Institute of Chemical Technology, Hyderabad, a leader in Chemical Technology which is welt known all over the world.

NIPER is now inviting applications for faculty positions on contractual basis initially for a period of one year which is likely to continue based on the performance of the selected candidate.

The U.S.Pharmacopeial Convention (USP) is a scientific nonprofit organization that sets standards for the identity, strength, quality, and purity of medicines, food ingredients, and dietary supplements manufactured, distributed and consumed worldwide. USP’s drug standards are enforceable in the United States by the Food and Drug Administration, and these standards are used in more than 140 countries.

Post : Director, Science - Chemical Medicines

Piramal Life Sciences Limited (PLSL) is an independent research-driven drug company that was recently demerged from Piramal Healthcare Limited (Formerly known as Nicholas Piramal India Limited). PLSL was formerly the NCE R&D division of NPIL. PLSL has state-of-the-art R&D laboratories built over 200,000 square-feet of space in Mumbai, India and over 300 scientists engaged in drug discovery and development.

Post : Executive-Q.A

{ DOWNLOAD AS PDF }

ABOUT AUHTORS
Seema Farheen¹*, Shaik Zubair¹ , Alwala Arpini¹, Govindapuram Kalpana  Goud²,  Saidulu Soppari³, Mangulal Kethavath^4
1Department  of pharmaceutics,
Vijaya College Of Pharmacy, Ranga Reddy, Telangana, India.
²Department  of pharmaceutical Analysis and Quality Assurance,
SLC’S College Of Pharmacy, Nalgonda, Telangana, India.
³Department  of pharmacology,
SLC’S College Of Pharmacy, Nalgonda, Telangana, India.
⁴Department  of pharmaceutics,
SLC’S College Of Pharmacy, Nalgonda, Telangana, India
*seemafarheen75@gmail.com

ABSTRACT
Atomoxetine hydrochloride (atomoxetine) increased the risk of suicidal ideation in short-term studies in children or adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD). Tablets of Atomoxetine Hydrochloride were formulated as sustained release tablet employing tamarind seed polysaccharide, guar gum, PVP, Mg. stearate, MCC  the sustained release tablets was investigated. Sustained release matrix tablets contain Atomoxetine Hydrochloride were developed using different drug polymer concentration of tamarind seed polysaccharide, guar gum,. Tablets were prepared by directly using MCC. Formulation was optimized on the basis of acceptable tablet properties and in-vitro drug release. The resulting formulation produced robust tablets with optimum hardness, thickness consistent weight uniformity and low friability. All tablets but one exhibited gradual and near completion sustained release for Atomoxetine Hydrochloride, and 98.6% and 97.5 released at the end of 12 hrs. The results of dissolution studies indicated that formulation F8, the most successful of the study. An increase in release kinetics of the drug was observed on decreasing polymer concentration