Hyderabad

Career for Masters in pharmacy/ Bachelors of Pharmacy as Team Member - Process Development in Mylan

Mylan is one of the world’s leading generics and specialty pharmaceutical companies, providing products to customers in more than 150 countries and territories. The company maintains one of the industry’s broadest and highest quality product portfolios, which is regularly bolstered by an innovative and robust product pipeline.

ANTIDEPRESSANT ACTIVITY OF POLYHERBAL EXTRACT ON RODENTS

About Authors:
A.Tamil Selvan*, R.Suresh1, D.Benito Johnson2, R.Suresh Kumar3, R.Venkatanarayanan4, L.Sivakumar5
Department of Pharmacology
Teegala Ram Reddy College of Pharmacy, Meerpet, Hyderabad – 97
1-4RVS College of Pharmaceutical Sciences, Sulur, Coimbatore- 641402
5SKM Siddha and Ayurvedha Company (India) Limited, Erode - 638104.

*tamilselvanpharmacologist@gmail.com

ABSTRACT
In this study, polyherbal extract of Cycas circinalis, Nardostachys jatamansi and Artemisia absinthium ethanolic fraction was explored for its antidepressant property using Forced swim test (FST) and Tail suspension test (TST). Many of its individual constituents have been used for central nervous system (CNS) activities but no systematic work was carried on this combination. In this study its effect on depression was explored in rats. For this purpose the plants part were extracted by successive solvent extraction by Soxhylation. Ethanolic extract was chosen for the pharmacological evaluation, based upon the phytochemical and instrumental analysis. The ethanolic extract was subjected to FT-IR analysis for finding the possible number and nature of function groups present in it. Also the extract was analysed by HPLC for the number possible phytocompounds/phytoconstituents present, which may directly or indirectly involve in the brain neurochemical activity. Acute and Subacute toxicity study revealed the dose upto 2000mg/kg the extract had not toxic symptoms and no mortality. The therapeutic dose was found to be 200mg/kg and there was no toxic damage to liver and kidney observed in subacute toxicity study. The ethanolic extract of the polyherbal combination exhibited significant (P<0.001) antidepressant activity  as indicated by its ability to decrease swim stress and tail suspension induced immobility time in rats as compared with that standard Fluoxetine. As well as restoring biogenic amines to normal level that was altered by the swim stress and tail suspension test in whole rat brain assay by HPTLC method. The result indicates this polyherbal combination can be a potential candidate for .managing depression. However further studies are required to confirm the exact therapeutic efficacy.

Career opportunity as Quality Assurance Manager in Procter and Gabmle (P&G)

Procter & Gamble is the innovation leader in our industry. Virtually all the organic sales growth we’ve delivered in the past nine years has come from new brands and new or improved product innovation. We continually strengthen our innovation capability and pipeline by investing two times more, on average, than our major competitors.

Research Associate (RA) in CSIR sponsored research project at The University of Hyderabad

The University of Hyderabad (UoH), one of the major institutions of higher education in India is largely devoted to postgraduate studies and is widely known for its excellence in research and for its distinguished faculty. Founded in 1974 with Prof. Gurbaksh Singh as its first Vice Chancellor, UoH - also known as Hyderabad Central University or HCU- has emerged as a leading centre of teaching and research.

Area Sales Manager require in Synergy Diagnostics | All India Level

Synergy Diagnostics pvt Ltd, a Bio-pharmaceutical company, with the Largest range of human blood plasma derived bio-pharmaceutical products, used in the prophylaxis & treatment of various life-threatening conditions.We are basically in to Sales & Marketing of imported products Manufactured from Human Blood. Products manufactured are injectable & critical care products.

Work as Area sales Executive/Medical representative in Synergy Diagnostics - Freshers may apply

Synergy Diagnostics pvt Ltd, a Leading Bio-pharmaceutical company, with the Largest range of human blood plasma derived bio-pharmaceutical products, used in the prophylaxis & treatment of various life-threatening conditions.We are basically in to Sales & Marketing of imported products Manufactured from Human Blood. Products manufactured are injectable & critical care products.

OXAZOLE – ISOXAZOLE: MOLECULE OF DIVERSE BIOLOGICAL ACTIVITIES

About Authors:
*C.P.Meher,  S.P.Sethy,  S. M Ahmed
Department of pharmaceutical Chemistry, Maheshwara college of Pharmacy,
chitkul (V), Isnapur “X” Road,  patancheru, Hyderabad.
*chaitanyameher84@gmail.com

ABSTRACT:-
Heterocyclic chemistry is vastly expanding because of the enormous amount of research work being done in this area. Heterocyclic compound are very widely distributed in nature and are particularly important because of the wide variety of physiological activities associated with this class of substances . A great deal of research is carried out to prepare new heterocyclic molecules having therapeutic uses.[1] and also so many heterocyclic derivative are synthesized till now having desired pharmacological effect. Out of them oxazole & isoxazole derivatives are catagorised in a higher position as the other heterocyclic compound possess in the hetero-chemistry. The present review is concern with the comparative study of the derivative of oxazole & isoxazole derivatives  along with their pharmacological effects.

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