Hyderabad

LIQUISOLID COMPACT: A NEW APPROACH TO ENHANCEMENT OF DISSOLUTION OF POORLY WATER SOLUBLE DRUGS

About Authors:
Nareshkumar. G1*, A.Eashwar rao2, Ch.Ganga prasad3.
1*Center for Pharmaceutical Sciences, IST, JNTU Hyderabad, India,
2Talla Padmavathi College of Pharmacy, Warangal, India,
3National College of Pharmacy, Shimoga, Karnataka, India.
*nareshkumar62@gmail.com

ABSTRACT:
Liquisolid technique is a new and propitious method that can change the dissolution rate of poorly water soluble drugs. According to the new formulation method of liquisolid compacts, liquid medications such as solutions or suspensions of water insoluble drugs in suitable non-volatile liquid vehicles can be converted into acceptably flowing and compressible powders by blending with selected powder excipients. It has been speculated that such systems exhibit enhanced release profiles. In this case, even though the drug is in a solid dosage form, it is held within the powder substrate in solution or, in a solubilized, almost molecularly dispersed state, which contributes to the enhanced drug dissolution properties. Successful liquisolid tablet is a determination of optimal flowable liquid retention.

Job as Project Fellow in Osmania University

Osmania University, established in 1918, is the seventh oldest in India, the third oldest in south India and the first to be established in the erstwhile princely state of Hyderabad. Throughout its existence of over eight decades, it has shown remarkable progress and sustained an integrated development of all faculties. It has significantly contributed to the academic and economic development of not only the region but also of the Country.

Vacancy for Quality Specialist, Process QM in PAREXEL

PAREXEL has developed significant expertise to assist clients in the worldwide pharmaceutical, biotechnology and medical device industries with the development and launch of their products in order to bring safe and effective treatments to the global marketplace for the patients who need them. Headquartered near Boston, Massachusetts, PAREXEL operates in 71 locations throughout 54 countries around the world, and has over 9,500 employees.

Career at Parexel as a Clinical Data Analyst - I

PAREXEL has supported the Bio-Tech and Pharmaceutical industries in helping the development of new drugs and treatments on a global basis. As a leading global biopharmaceutical service provider, they supply knowledge-based contract research, medical communications and consulting services across a broad range of therapeutic areas to the worldwide pharmaceutical, biotechnology and medical device industries.

AN OVERVIEW OF LIQUID CHROMATOGRAPHY COUPLED WITH TANDEM MASS SPECTROSCOPY (LC-MS/MS)

About Authors:
*S.B.Muthu Vadivel, R.Suresh Kumar, A.Tamil Selvan, R.Suthakaran
Department of Pharmaceutical Analysis and Quality Assurance
Teegala Ram Reddy College of Pharmacy
Saroor nagar, Meerpet, Hyderabad – 97.
*muthuvadivelanalyst@gmail.com

Abstract
Mass spectrometry has been applied to almost every area of research being pursued today. Studies of diverse subjects, such as cancer research, identification of drugs, forensic analysis, atmospheric end-water environmental analysis, combustion, and lasers have benefited from mass spectrometry. In some of these studies, the mass spectrometer is used both as a chemical reactor and as an analytical instrument. Because of these diverse applications, no person or group can completely review the field of mass spectroscopy. This chapter discusses instrumental designs and techniques, ionization processes, ion–molecule reactions, high-temperature systems, and sampling of reactive species. Any tandem mass spectroscopy has four basic components: (I) a system by which the sample to be studied is introduced into the instrument, (II) an ion source where ions that are characteristic of the sample are produced, (III) an analyzer region where the ion beam is sorted into its various mass-to-charge ratios, and (IV) a detector system where the separated ion beams are collected and by some method, rendered observable.

Walk in interview for Junior Research Fellow in National Institute of Nutrition | 12 Posts

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr. McCarrison as its first Director. It was shifted to Hyderabad in 1958.

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