About Authors:
SHARMA AKANSHA*, AGRAWAL SHIKHA
SWAMI VIVEKANAND COLLEGE OF PHARMACY
KHANDWA ROAD INDORE (M.P.)
*akansha.sharma@mylan.in

ABSTRACT :
The main aim for performing this project is to increase the bioavailabilty of lamotrigine as well as its onset of action to control the seizures that occur during the epileptic attack. To serve this purpose we will use mucilage of oscimum basilicum as a natural superdisintegrant & later comparing it with different novel synthetic superdisintegrant. By preparing a rapid disintegrating tablet of lamotrigine, rapid action of same can be achieved easily.
As we know that superdisintegrant plays the major role in rapid disintegration of tablet, thus it is very important to select a right or correct superdisintegrant in all respect which fulfill its purpose without effecting other parameters of tablet formulation and gives quicker and better result, when the number of formulation with different combinations of superdisintegrants (Natural & Synthetic) will be made then it would become very easy to evaluate and get the formulation with maximum desirable results.Lamotrigine being a poorly water soluble drug, needs modification to make them water soluble.

The University holds the distinction of being the first distinction of being the first Women University in North India.
The first Academic Session of the University commenced in August 2007 and since then the University has progressed by leaps and bounds. The University, already recognized under Section 2(f) of the UGC Act, 1956 became the quickest University to get recognition under Section 12(B) of the UGC Act, 1956.

Advinus Therapeutics (A TATA Enterprise) is an R&D driven company that is focused on the new drug discovery and development of pharmaceutical and agrochemical products. Advinus operations are organized into two separate businesses centered around Discovery and Development respectively.

About Authors:
Jigar Modi^*1, Dr. Jayvadan Patel¹, Dr. Hitesh chavda^2
1Nootan Pharmacy College, S.P. Sahkar Vidhyadham,
Kamana Crossing, Visnagar-384 315,
Dist – Mehsana, Gujarat, India.
²Shri Sarvajanik Pharmacy College,
Nr. Arvind Baug, Mehsana, Gujarat, India
*jigo_farmacy@yahoo.com

ABSTRACT:
Generally, controlled release dosage forms used in many applications. Superporous hydrogel is also one of them. It has lot of advantages over conventional hydrogel. Superporous hydrogel having faster swelling due to interconnected highly porous structure. Such other properties like slippery property, their mechanical strength and better foaming process are advantageous over conventional hydrogel. Its unique mechanism for achieving gastric retention, a number of hurdles have to be overcome for any approach to be clinically useful. For example, intra-gastric floating systems require the presence of gastric juice to be effective, and this may not be the case in the fasted state. Mucoadhesive systems can easily lose their mucoadhesive properties by interaction with any materials soluble in gastric juice. In this review, types of superporous hydrogel, their preparation, their characterizations and applications are discussed.

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The PGIMER owes its inception to the vision of late Sardar Partap Singh Kairon, the then Chief Minister of Punjab and the distinguished medical educationists of the then combined state of Punjab, supported by the first Prime Minister of India Pt. Jawahar Lal Nehru who considered the institutions of scientific knowledge as temples of learning and the places of pilgrimage.

The spark for launching professional education (Management & Pharmacy), both at the undergraduate and post-graduate level at Lloyd has come from Academicians and Business Leaders who felt that the current trend in higher education is only limited to Books, Classes and Exams, that needs to be replaced by more meaningful education so that students are mounded to not only become better professionals but also good human beings at a relatively young age..

Synokem Pharmaceuticals, founded in 1982 is an emerging pharmaceutical company with proven capabilities in the areas of manufacturing and marketing. It’s among the fast growing pharmaceutical company in India, which has grown from strength to strength and diversified its activities.
Synokem Pharmaceuticals Ltd., a 100 crore, progressive, 28 years old organization with all India operations requires for its different

Sanvin Group is a family owned business engaged as a manufacturer and exporter of API, chemical intermediates, and specialty chemicals since 1994. Our export market is widespread in the latitudes and longitudes of Europe, The Americas, Far East Asia and Middle East.

About Authors:
Mr.Sanjay wasudeo upare^*, Dr.A.V.Chandewar, Dr.M.D.Kshirsagar, Mr.U.S.Koli and Mr.H.K.Pokale
M-Pharm IV semester (Pharmaceutics department)
Pataldhamal Wadhwani college of Pharmacy,
Yavatmal
*uparesanju81@gmail.com

ABSTRACT:
Lornoxicam is a non steroidal anti-inflammatory drug with analgesic properties. The purpose of this study was to develop a taste masked oral disintegrating tablet of poorly soluble Lornoxicam by direct compression technique with β-cyclodextrin (BCD) complexes using various super disintegrants like sodium starch glycolate, crospovidone and L-Hpc. Prepared tablets were evaluated for different properties like drug content, hardness, friability, disintegration time and in vitro dissolution study. The different formulations showed disintegration time between 21 to 33.66 s. Drug release showed time between the ranges of 5 to 30 min. Among all the formulations, L1 showed 97.79% drug release within 30 min. Thus, L1 was considered best among the other formulations.. The tablets showed enhanced dissolution hence better patient compliance.

About authors:
1.Shashi Kant*, Satinder Kumar,
Research scholar department of pharmacy.
2. Dr. Bharat Prashar
HOD & Associate professor 
Department of Pharmaceutical Sciences,
Manav Bharti University, Solan (H.P)
shashi_ranaute@yahoo.in

ABSTRACT :
In this review article we discussed about are monospecific identical immune cells that are all clones of a unique parent cell. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular the non-proprietary drug name ends in mabs,in this we discussed type of monoclonal antibodies,preparation,targeting of monoclonal antibodies as well as advantages and disadvantages of monoclonal antibodies. antibodies that are biology and medicine.

Biocon is a research-driven, global healthcare company with a strong matrix of capabilities along the biopharmaceutical value chain. Focusing on unmet medical needs in cancer, diabetes and inflammatory diseases, it offers novel therapies on a platform of affordable innovation.

Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals.

About Authors:
Joshi B.*, Agarwal P., Sahu D., Dashora A.
Geetanjali Institute of Pharmacy,
Udaipur Rajasthan, India
*bhavesh.joshi8@gmail.com

Abstract:
Antiaging is emerging class of cosmetics which combine the benefit of anti aging ingredients with the elegance skin feel and delivery system of cosmetics antioxidants, anti cellulites and anti microbial have been use in maintaining and enhancing human beauty. Anti aging ingredients also help to reduce the fine lines, increasing the moisture level and reduces wrinkles and puffness to keep the skin in good condition. New delivery system is a more effective solution for the skin aging resulting from photoaging. New vehicle like liposome and nanoparticles is a new generation for antioxidants with enhanced bioavailability and very stable activity. Our objective is to review present state of the art knowledge pertaining to mechanisms involved in skin aging, factor responsible for aging and various new ingredients use to treat aging defect.

About Authors:
Sachin Kaushik*, Dr. shivakumar Hugar
P.G. Department of Pharmacology,
B.L.D.E.A.’s college of Pharmacy,
Bijapur- 586103,
Karnataka,India
*sachin_2004_kaushik@yahoo.com

ABSTRACT:
In the present study antistress activity was assessed against anoxia tolerance, swimming endurance and cold restraint stress models. In anoxia tolerance test, the mean time of appearing first convulsion in mice was taken as end point to determine the time of anoxia.  In swimming endurance test the mean time of swimming performance was recorded.The end point taken was when the animals remained at the bottom of swimming tank for 10 sec. Biochemical estimation like glucose, cholesterol, triglycerides and BUN and weight of organs were measured in cold restraint stress model.

Fresher Post Graduate in Pharmacy / Chemistry invited as Associate Scientist in CavinKare

Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals.