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Synthesis and evaluation of carbodithioic acid esters of naphthylmethylamine, a novel class of spermicides

About Authors
M. M. Singhal, Monica Gupta
Department of chemistry,
Delhi Institute of Pharmaceutical science & Research,
New Delhi, India

Affiliation Affiliated from Govt. of NCT Delhi

Abstract :
Carbodithioic acid esters of naphthylmethylamine prepared by replacing the amino function in amino methyl side chain with carbodithioic acid ester group and by adding various S-2-hydroxy propyl ester of dialkyl carbodithioic acid at amino group. Some of these compounds showed better spermicidal activity. The study revealed that incorporation of carbodithioic acid residue directly into naphthylmethylamine leads to compounds with better spermicidal activity and naphathalene-1-yl-methyl-carbodithioic acid-3-dialkyl amino-2-hydroxy-propyl ester has shown better profile than nonoxynol-9. Further, lead optimization may yield a potent spermicide.

MOBILE PHONE & BRAIN TUMOUR

About Authors:
Ankit Kumar Jhangta,
M.Pharm
Kumaun Univ. Nainital

ABSTRACT
Mobile telecommunication technology became commercially available about 20-30 year ago in different countries around the world commencing with europian countries. Telecommunication Industry has grown by leaps and bound over the last decade. Thus any health hazard from these devices promises  to have large
epidemiological impact as more than half of the population are mobile users.The key aim of this paper is to scientifically and objectively review data suggesting or refuting a relationship between mobile phone usage and brain tumours.

Eclipta alba (L.) A review on its phytochemical and pharmacological profile

About Authors:
Mithun NM*, Dr.Shashidhara S1

Dept. of Pharmacognosy,
Government college of pharmacy,
Bangalore

Abstract: Eclipta alba (L.) is small branched annual herbaceous plant with a long history of traditional medicines uses in many countries especially in tropical and subtropical regions. The herb has been known for its curative properties and has been utilized as antimytotoxic, analgesic, antibacterial, antihepatotoxic, antihaemorrhagic, antihyperglycemic, antioxidant, immunomodulatory properties and it is considered as a good rejuvenator too. Recent studies showed an antivenom property & corrosion pickling inhibitor action on mild steel in hydrochloric acid. A wide range of chemical compounds including coumestans, alkaloids, thiopenes, flavonoids, polyacetylenes, triterpenes and their glycosides have been isolated from this species. Extracts and metabolites from this plant have been known to possess pharmacological properties. This contribution provides an comprehensive review on ethnomedicinal uses, chemical composition, and the pharmacological profile as medicinal plant. Particular attention is given to antihepatotoxic, analgesic, antioxidant , antihyperglycemic, antiaggresive, wound healing properties and insecticidal effects presented in this review such that the potential use of this plant either in pharmaceutics or as an agricultural resource can be evaluated.

Applications are Invited in Tezpur University for the post of JRF

Tezpur University was established by an Act of Parliament in  1994.

Area Sales Manager Required in Novartis Healthcare

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Career as Assistant Manager - Quality Assurance & Compliance at Novartis healthcare

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Opportunity in Glenmark as Clinical Research Associate (Clinical Research-Drug Discovery)

Glenmark is a leading player in the discovery of new molecules both NCEs (new chemical entity) and NBEs (new biological entity) with eight molecules in various stages of clinical development. The company has a significant presence in branded generics markets across emerging economies including India. Its subsidiary, Glenmark Generics Limited has a fast growing and robust US generics business. The subsidiary also markets APIs to regulated and semi-regulated countries.

Research Associate-Analytical Development require in Famy care - 4 openings

Famy care is a global player in the Female Health Care Segment with a focus on Hormonal & Reproductive Health Care Products. Famy care believes in the right of women to be informed about their reproductive healthcare choices and to make good health accessible to all. In a very short span of time we have become the largest manufacturer of Hormonal Tablets.

Work in Neon Laboratories Ltd. as Professional Service Executive / Medical Representative |100 Openings|

NEON was incorporated in 1982 at Bombay. In 1984, few if any at all would have taken note of a company that had just released it’s first production batch, of Anaesthetic Product,in the market.
NEON is promoted by Jains, a well established business family, who has been associated with Pharmaceutical Industry for the last four decades,having wholesale pharmacy in various parts of the country, under the leadership of Mr. B K Jain, the Chairman Cum Managing Director.

Job in Quintiles as Clinical Data Coordinator - 10 openings

Quintiles is the only fully integrated biopharmaceutical services company offering clinical, commercial, consulting and capital solutions worldwide. Our network of 23,000 engaged professionals in 60 countries around the globe works with an unwavering commitment to patients, safety and ethics — ensuring a higher level of healthcare for people. For our biopharmaceutical customers, we help them navigate risk and seize opportunities in an environment where change is constant.

Admission Notification in Jamia Hamdard: Application invited for Admission in B.Pharm, D.Pharm, M.Pharm, Ph.D

Applications have been invited by Jamia Hamdard University, New Delhi, for admission to the following courses of Academic Year 2011-12 from the candidates eligible as mentioned against each course:

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PHARMACY:

Opportunity as Associate - Clinical Trial Labeling in Lilly, Indianapolis

Lilly USA, LLC has been dedicated to meeting the health care needs of people in the United States and around the world. We address these needs primarily by developing innovative medicines—investing a higher percentage of our sales in research and development than any other major pharmaceutical company. If you are interested in being considered for employment with a “Best in Class” Pharmaceutical company, please review the following opportunity:

Regional Sales Manager required in Celestial Biolabs Ltd

Celestial Biolabs Ltd is an ISO 9001-2001 certified listed company with NSE and BSE company ,Celestial has been providing customized IT solutions for Pharma, Bio-pharma, Biotech and manufacturing, Now Expanding business in Pharma Exports.

Post: Regional Sales Manager

Require Production Pharmacist in Emcure- 2 openings

Emcure are fortunate to have a very passionate and talented team. Emcure is committed to emerge as the most preferred employer. We have conducted several training programs and also taken policy decisions towards creating a better work life balance for our people.

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