KlinEra has been partnering with pharmaceutical, biotech and device companies since 1999, providing innovative and customized clinical services to their client’s. Today, a decade’s presence in the Clinical Research Arena has made it a mature, comprehensive, creditworthy clinical research organization with offices in Mumbai, India and in San Jose, CA, USA.

The Council's Regional Medical Research Centre for Tribals set up, in 1984, at Jabalpur, addresses itself mainly to the study of the health and nutritional problems of the tribal populations, including nutritional disorders, common communicable diseases, environmental health problems, etc. This Centre provides assistance in planning, monitoring and evaluation of tribal health and other developmental programmes in tribal areas of India (including Madhya Pradesh) and also in training health functionaries.

The National Institute of Pharmaceutical Education & Research (NIPER) is an Institute of National Importance by an Act of Parliament under the aegis of Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, Government of India. The institute is located at S.A.S. Nagar, Punjab adjoining Chandigarh the City Beautiful.

ICMR has established eight Biomedical Informatics centres at SGPGI Lukhnow, PGI Chandigarh, AIIMS New Delhi, NIRRH Mumbai, TRC Chennai, NICED Kolkata, NIN Hyderabad, RMRC Patna and a coordinating unit at ICMR Hqrds, New Delhi. The centres were established with objectives:
*To develop new methodologies and solutions for prevention and amelioration of diseases of national importance
*To develop and support databases of specific clinical findings and Biomedical data

one post of SENIOR RESEARCH FELLOW under ICMR funded project entitled “National Network for genotyping of human lymphatic filarial parasite Wucherria gancrotti from different endemic areas”.  The selected candidates will be appointed for a period of one year only.

Post: SRF

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Recognising the high incidence of tuberculosis around Dharmasthala, a modern TB Sanatorium was established at Laila under the aegis of the Shri Dharmasthala Manjunatheshwara Medical Trust. Now it has been turned into a general hospital since April 2003 as private institutions are not allowed to treat tuberculosis patients.

About Authors:
Rakesh Bhatia
School of Pharmaceutical Sciences, Department of Chemistry,
Jaipur National University, Jaipur-302025,
Rajasthan, India

ABSTRACT
QSAR has been applied extensively and successfully over several decades to find predictive models for activity of bioactive agents. QSAR have brought revolution in drug discovery process by thedevelopment of mathematicalrelationships linking chemical structures and pharmacological activity in quantitative manner of series of compound. The mathematical relationships between molecular descriptors and activity are used to find the parameters affecting the biological activity and/or estimate the property of other molecules. Description of the molecular structure, electronic orbital reactivity and the role of structural and steric components have been the subject of mathematical and statistical analysis. This review seeks to provide an evolution of QSAR and development of receptor theory.

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KlinEra has been partnering with pharmaceutical, biotech and device companies since 1999, providing innovative and customized clinical services to their client’s. Today, a decade’s presence in the Clinical Research Arena has made it a mature, comprehensive, creditworthy clinical research organization with offices in Mumbai, India and in San Jose, CA, USA.

ANSWERS of Previous PharmaQUIZ-34:

1.A    2.A    3.B    4.B    5.C

6.D    7.A    8.A    9.D    10.A

Undergraduate or Postgraduate Scholarship for students from Canada , China , India , USA in Different subjects at National University of Ireland, Galway 2012

Study Subject: Various

About Authors:
Soujanya J, Silambujanaki P, Leela Krishna V
Department of Pharmacology, SRM College of Pharmacy,
SRM University, Kattankulathur-603203,
Kancheepuram Dist.,
Tamil Nadu, India

Abstract
Holoptelea integrifolia, Planch. is a widely used herb in traditional medical systems of India.It is an important pollen allergen of India andsensitizes almost 10% of the atopic population in Delhi.Various parts of Holoptelea integrifolia, a roadside plant, are indicated by Charaka Samhitha, Sushrutha Samhitha and other traditional systems for the treatment of inflammations, acid gastritis, dyspepsia, flatulence, colic, intestinal worms, vomiting, wounds, vitiligo, leprosy, filariasis, diabetes, haemorrhoids, dysmenorrhoea and rheumatism.The present review is therefore, an effort to give a detailed survey of the literature on its pharmacological, traditional and phytochemical properties

About Authors:
Das Saumya¹*, Basu saumya Priya¹, Das Manas Kumar², Das Sanjita¹
1. Institute of Pharmaceutical Technology, NIET, Greater Noida, U.P., India.
2. Department of Pharmacy,
IEC-CET,
Greater Noida, U.P.,
India.

Introduction
Cancer has been one of the greatest scourges of mankind since time immemorial. It may be regarded as a series of malignant diseases characterized by (i) abnormal growth of cells (ii) ability to invade adjacent tissues and even distant organs and (iii) the eventual death of the affected patient if the tumor has progressed beyond the stage where it can be successfully removed. The incidence of cancer is expected to rise worldwide notably because of increase in life expectancy, changes in lifestyle patterns and environmental factors. Over the years, an increased understanding of cancer at cellular, molecular and genetic levels is opening up enormous opportunities to interrupt its initiation and progression. Although rapid strides have been made in treatment of cancer, there still remain many stumbling blocks in achieving cancer prevention and cure.

Incorporated in November 1998, Epsilon Pharmaceuticals Private Limited is located at Jedcherla SEZ, near Hyderabad, Andhra Pradesh. With the advantage of location and a team comprising of experienced scientists and qualified professionals, Epsilon has robust infrastructure and broad technological strengths, capable of manufacturing a wide range of steriles in Oncology segment and also prescription drugs for its clients on contract basis.

Intas Pharmaceuticals headquartered at Ahmedabad (India), is now a force to reckon with, in the global pharma horizon. With expertise in a range of formulations, from tablets to injectables to newer drug delivery systems, Intas is currently ranked 18th among the Indian Pharma majors.

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr.

Sundyota Numandis is a new-age pharmaceutical company, leveraging its experience, expertise and energies to better people’s lives.
Since its foundation in 2003, Sundyota Numandis has grown exponentially in a very short span. With over 600 employees & 21 distribution centers across the nation reaching over 80,000 retailers, they are amongst one of the fastest-growing pharmaceutical companies today with a proven track record of success year after year.

La Pharma is engaged in the manufacturing & marketing of psychotropic products for over four decades. The company enjoys leadership status in most of the products, operating through a network of dedicated sales force and dealers, throughout the country.

About Authors:
Sachin Saxena*¹,Pankaj Sharma¹ ,Nimisha²
1-M Pharm (Pharmaceutics) , Amity Univerity,Lucknow
2-Lecturer,
Amity University,
Lucknow

Abstract:
Rapid developments in the field of molecular biology and gene technology resulted in generation of many macromolecular drugs including peptides, proteins, polysaccharides and nucleic acids in great number possessing superior  pharmacological efficacy with site specificity and devoid of unwanted and toxic effects. However, the main impediment for the oral delivery of these drugs as potential therapeutic agents is their extensive presystemic metabolism, instability  in acidic environment resulting into inadequate and erratic oral absorption. Parentral route of administration is the only  established route that overcomes all these drawbacks associated  with  these  orally  less/inefficient  drugs  but,  these   formulations  are  costly,  have  least  patient compliance, require repeated administration, in addition to the other hazardous effects associated with this route. Buccal drug delivery leads direct access to the systemic circulation through the internal jugular vein bypasses drugs from the hepatic first pass metabolism leading to high bioavailability. Buccal route is an attractive route of administration for systemic drug delivery. Buccal bioadhesive films, releasing topical drugs in the oral cavity at a slow and predetermined rate, provide distinct advantages over traditional dosage forms for treatment of many diseases.