REVIEW ON ANIMAL MODELS OF Dementia AND ALZHEIMER’S DISEASE
About Author:
Richa Shrivastava
National Institute Of Pharmaceutical Education And Research
Niper, Guwahati
richashrivastava18888@gmail.com
Dementia is defined as a loss of intellectual abilities that is severe enough to interfere with social or occupational functioning.
Alzheimer’s disease (AD) is most common cause of dementia. 50-70% of all cases of dementia are due to Alzheimer’s disease.
AD is characterized by early memory deficits, followed by gradual erosion of other cognitive functions. The most severe neuropathological changes occur in the hippocampus, followed by association cortices or subcortical structures, including the amygdale and nucleus basalis of Meyhert.

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