About Authors:
Ratnadeep V. Ghadage (M. Pharmacy)
Department of Pharmaceutical Chemistry,
Appasaheb Birnale College of Pharmacy,
South Shivaji Nagar, Sangli-416416,
Maharashtra

ABSTRACT:
Quinoxaline derivatives have emerged as an important class of benzoheterocycles because of their diverse pharmacological and biological properties, which make them privileged structures in combinatorial drug discovery libraries. Also Quinoxaline derivatives constitute useful intermediates in organic synthesis. The pharmaco-logical importance of quinoxalines and their utility as building blocks in organic synthesis have directed considerable research activities toward the synthesis of suitably substituted quinoxaline rings. Extensive researches have generated numerous synthetic approaches for the construction of the skeleton of such heterocycles. Quinoxalines are, in general, comparatively easy to prepare, and numerous derivatives have been designed and prepared for potential use as biologically active materials. Oxidation of both nitrogen of the quinoxaline ring dramatically increases the diversity of certain biological properties.
Quinoxalines, including their fused-ring derivatives, display diverse pharmacological activities.A number of synthetic strategies have been developed for the preparation of substituted quinoxalines. The classical synthesis of quinoxalines involves the condensation of an aromatic 1, 2-diamine with a 1, 2-dicarbonyl compound. The reaction is facile and is the most widely used synthetic method for both quinoxaline itself and its derivatives. Despite remarkable efforts,the development of an effective method for the synthesis of quinoxalines is still an important challenge.

HLL Lifecare Limited is a Mini Ratna Company of Govt. of India under the Ministry of Health & Family Welfare. HLL, a schedule B Public Sector Enterprise is today a multi product, multi unit organization addressing various public health challenges. The company with five manufacturing units and marketing offices throughout the country is engaged in the manufacturing and marketing of a wide range of contraceptives and healthcare products.

IIT Bombay, set up by an Act of Parliament, was established in 1958, at Powai, a northern suburb of Mumbai. Today the Institute is recognised as one of the centres of academic excellence in the country.

The  Department  of  Ayurveda,  Himachal  Pradesh,  Shimla-9 invites  the  applications  from  the  desirous/eligible  for  the  posts  and  categories mentioned below:

Post: Pharmacist - total 54 posts

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Banaras Hindu University ranks among the first few in the country in the field of academic and research output.

About Author:
Rajesh Mujoriya
Sardar patel college of technology,
Balaghat, dis. Balaghat,
MP–481001,INDIA

Abstract
A neoplasm or tumor is a abnormal mass of tissue, the growth of which exceeds and is uncoordinated with that of the normal tissue and continues in the same manner after cessation of the stimuli which have initiated it.
A malignant tumor grows rapidly and continuously, and even when it has impoverished its host and source of nutrition, still retains the potentiality for further proliferation. Besides, malignanat tumors invade and destroys neighbouring tissues and possess no effective capsule, a malignant tumors readily ulcerate and tend sooner or later dessiminate and form metastases.

Venus start each day by focussing on Innovation & Creativity. We make sure that best healthcare is provided to our patients worldwide.
From a humble beginning in 1991, now we are engaged & engrossed in discovering, developing and delivering innovative pharmaceuticals that help patients to alleviate sufferings.

HLL is aiming to be a global leader in the area of contraceptives and healthcare products. The IBD manages the distribution of HLL's products to over 115 countries worldwide. HLL has also made inroads into Peru in South America, for its Non-steroidal Contraceptive Pill marketed here under the brand name Ivyfemme. HLL supplies its products to world bodies such as the UNFPA, PSI, Mission Pharma and IDA, in addition to various governmental procurement organizations.

About Authors:
Rajkumar Bolledula*, Priyanka.Mare¹, Sunanda.Mare²
*Department of pharmaceutical analysis, Assistant professor in MITS college of pharmacy, H.No.41-64-s, saibabanagar, Kurnool-518004, A.P, India.
1.Department of pharmaceutics, Assistant professor, Mits college of pharmacy, Block .no.mc2/2, singareni colony, tekulapally,yellandu,khammam-507123,A.P,India
2.Department of pharmacology, J.K.K.Natarajan college of pharmacy, Salem, Tamil Nadu

ABSTRACT
This article describes the quantitative determination of percentage of drug concentration in pure and in formulated pharmaceutical dosage forms by using RP-HPLC. Procedure does not require prior separation of components from the sample.The mobile phase consists of methanol-water (80:20 v/v) for RP-HPLC with injection volume of 20μl.The RP-HPLC method was developed on a C-8 (150x4.6mm) column with detection carried out by variable wavelength detector at 209nm and 220 nm for ramipril, cardace, odopril respectively…Thus the Rt values obtained for different dosage forms are 1.59,1.44,1.34,1.35…..respectively with the concentration of 100% for pure drug and 97.54%,91.03%,65.76%.......respectively.

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About Authors:
Jatin Sharma*, Dharmendra kumar{Sr. Lecturer}, Amarjeet Singh
School of Pharmaceutical Sciences Shobhit University,
Meerut

Abstract
Objective: Clerodendrum serratum.(L)belong to family Verbenaceae a have long history as source of potential chemotherapeutic agents in Ayurvedic and Unani system of medicine.Clerodendrum serratum (L), Ban-Bakri is commonly known as Bharangi in Hindi and Bhargavi in Sanskrit. It is found from 1000 to 1800 meters above mean sea level. It is distributed in warmer regions of Deccan and Carnatic, West Coast districts of Tamil Nadu, Kumaon, Sikkim, and Assam.Clerodendrum serratumis one of the important plants from traditional system of medicine found all over the world.

Keyfinding: This review is intended to provide the currently available information on traditional and local knowledge, ethnobotanical and ethnomedical issues, identification of pharmacologically important molecules, and biochemical and pharmacological studies of this useful plant.

Summary: Clerodendrum serratum has been cited in many indigenous systems of health care for the treatment of variety of disorders. An extensively used as folk medicines for years have been investigated for their chemical constituents and biological activity to confirm these traditional claims.

Applications are invited from Indian nationals for the following non-teaching posts on direct recruitment / deputation / contract basis in the Pay Band and Grade Pay indicated against each of the post plus usual allowance at Central Government rates.

Applications are hereby invited from eligible candidates for recruitment to various posts in different Departments under Government of NCT of Delhi and, its autonomous/local bodies. The details regarding name of the post(s), post code, Department, number of vacancies, educational qualifications, experience required, pay scale, age limit etc. as per the Recruitment Rules provided by the user department are given at Section A of this Advertisement.

Applications are invited for the posts of Professor, Associate Professor and Assistant Professor, which are being recruited on Regular basis in the School of Computational Sciences, Education, Social Sciences (Sub- Centre, Latur ), Social Sciences (University Campus), Technology (Sub-centre, Latur), Mathematical Sciences (Mathematics & Statistics), Physical Sciences, Life Sciences, Earth Sciences, Language & Literature [Marathi/English], Management (Sub-Centre, Latur), and Pharmacy of this University.

About Author:
Mr. RAJU A. MODHAVADIYA
School of Life Sciences
University of Hertfordshire, UK

Abstract:
The main concept of the study was to find out the penetration of boots ibuprofen gel at different frequencies such as 20 kHz and 40 kHz through cellulose membrane exposed to ultrasound. Different sonicator bath were used for different frequencies. Ultrasound has been used to enhance penetration of ibuprofen from transdermal preparation. Boots ibuprofen gel was used in the experiment. Ibuprofen is a NSAIDs drug which is used to enhance healing effect against inflammation, pain and analgesics.
Frequency, intensities, duty cycle are the important factor. In this experiment frequency variable was used. 20 kHz and 40 kHz frequencies were used in this experiment.Boots ibuprofen gel max (10%) was used to measure the penetration of ibuprofen through the cellulose membrane exposed to ultrasound. By using the Franz diffusion cell penetration of ibuprofen was found out. An amount of ibuprofen permeated through cellulose membrane was found out using High Performance Liquid Chromatography (HPLC).       Penetration of  ibuprofen was found out more lower frequency.  However the penetration ibuprofen also increase compare to control in first hour. The ANOVA result: sample assuming equal variances were performed to find out significance difference (P<0.05) between control and different ultrasound frequencies and also the rate gradients were measured. The P value got for the control and 40 kHz frequency was 0.123, which indicate that there is no significance difference observed for permeation of ibuprofen from gel . P value of control and 20 kHz frequency applying for 2 min was 0.05 which was similar P value, which shows that nearly significance observed between two value. The P value of control and 20 kHz for 5 minute was 0.002 which indicate that there was a significance observed between this two value.   From the result it shows that lower frequency with more time give good penetration result.

J. B. Chemicals & Pharmaceuticals Ltd. (JBCPL), known to many as Unique Pharmaceutical Laboratories is one of India's leading global pharmaceutical companies. The company manufactures and markets a wide range of pharmaceutical formulations.

Post: Manager Outsourcing

IICT invites applications from highly talented and research oriented candidates to join as Junior Research Fellow (JRF) to pursue PhD Program at IICT for the Academic Session starting from January 2012.  A brief profile of research activities at IICT is given in the Annexure enclosed.

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The Institute has completed successful 25 years.