Government of Haryana has set up a new Medical College at Khanpur Kalan in district Sonepat. It is a Government College for girls. The M.C.I. has given permission to admit 100 girls’ students for the academic year 2012-13 and the batch has already been started. The College is strategically located between two National Highways, GT road on eastern side and highway 71A from Rewari to Chandigarh on the western side, in green and naturally beautiful 100 acres land in absolutely pollution free area.

National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an ‘Institute of National Importance’.

King's College London was founded in 1828-9 by a group of eminent politicians, churchmen and others. They wanted to see a Church of England alternative to what later became University College London (UCL, founded in 1826), known as 'the godless college in Gower Street'. King's was granted a royal charter by King George IV on 14 August 1829.

A 3-year fellowship to complete Ph.D studies in medical molecular pharmacology is available at the Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, Faculty of Health Sciences.

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About Author:
Kabita Banik
B.pharm;(WBUT) BCDA College of pharmacy &Technology;
M.pharm(BPUT) Dadhichi college of pharmacy.
banikkabita64@gmail.com

Abstract:
New cancer targeted therapies that make use therapeutic antibodies or small molecules have made treatment more tumor specific and less toxic. Nevertheless, there remain several challenges to the treatment of cancer, including drug resistance, cancer stem cells, and high tumor interstitial fluid pressure. In many solid tumors, for example, increased interstitial fluid pressure makes the uptake of therapeutic agents less efficient. One of the most promising ways of meeting such challenges is ligand-targeted therapy that may be used to make targeting more specific and carry higher dosages of anti-cancer drug to tumor tissue.

About Authors:
Gunjan Kalyani*, Vishal S. Deshmukh, Pranita Kashyap, Ram D. Bawankar, Yogesh Vaishnav, Deepak Biswas
Shri Rawatpura Sarkar Institute of Pharmacy,
Behind power grid, Kumhari, Durg, Chhattisgarh
*kalyani.gunjan@yahoo.in

Abstract
Clopidogrel bisulfate is an inhibitor of adenosine diphosphate (ADP)-induced platelet aggregation acting by direct inhibition of ADP binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Objective of the present study is to develop a simple, sensitive, accurate, precise and rapid derivative spectrophotometric method for the estimation of clopidogrel in pure form. For the estimation of clopidogrel, solvent system employed was 0.1 N HCl and wavelength of detection (λ_det) was 284.3 nm for fourth order derivative spectroscopy. The linearity was obtained in the range 42 – 336 µg/ml. The limit of detection is 6.7 µg/ml and limit of quantification was fund to be 20.4 µg/ml. Obtained results showed that there is minimum intra day and inter day variation. The developed method was validated and recovery studies were also carried out. Sample recovery using the above method was in good agreement with their respective labeled claim, thus suggesting the validity of the method and non-interference of formulation excipients in the estimation. Fourth order derivative spectroscopic method is simple, rapid and reproducible and further it can be used for the analysis.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer. TMC is an autonomous grant-in-aid institution of the Department of Atomic Energy (DAE), Government of India.

Applications are invited for positions of Project assistant For a DBT sponsored project on Leishmanial proteins.

Position : Project Assistant (one post)

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About Authors:
Gunjan Kalyani*, Vishal S. Deshmukh, Pranita Kashyap, Ram D. Bawankar, Yogesh Vaishnav, Deepak Biswas
Shri Rawatpura Sarkar Institute of Pharmacy,
Behind power grid, Kumhari, Durg, Chhattisgarh
*kalyani.gunjan@yahoo.in

Abstract:
A simple, rapid and precise and accurate RP-HPLC method was developed for the estimation of candesartan. The method involves a simple technique using Irbesartan as internal standard. HPLC separation was achieved using C18 Intersil column (256 x 4.6 id) with an isocratic mobile phase composed of selected methanol: 10 mM Phosphate buffer [75:25 % v/v. pH 3.0] at a flow rate of 1.0 mL/min with UV detection was performed at 256 nm. The retention time of candesartan and internal standard was found to be 1.96 and 3.33 min respectively. The assay was validated for the parameters like accuracy, precision, robustness and system suitability parameters. The method was validated over a linear test concentration range of 80 - 120%. The recovery of the method was in between 99.0 - 101.0%. The proposed method was found to be accurate, precise, selective and rapid and it can be useful in the routine analysis for the determination of candesartan cilexetil in pharmaceutical dosage form.

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Aabout Author:
Dhirendra C. Patel*
Master of Pharmacy, Department of Pharmaceutics and Pharmaceutical Technology,
S.K. Patel College of Pharmaceutical Education and Research, Ganpat University,
Kherva, Mehsana, Gujarat, India.
dhiren.pharmacy@gmail.com

Abstract:
Herbal medicines are very popular in treatment of the asthma in the modern era because of lots of benefits of it like less cost, less side effects, easily available etc. Herbal alternatives to asthma are better way for treatment of asthma. Various herbal medicines recognize that immune system functioning can play a vital role in helping to control the symptoms of asthma and strengthen the body's defenses against environmental allergens. Herbal medicines like ephedra, ginger, chamomile, elderberry, licorice, mullein, stinging nettle etc are very beneficial in asthma. Scientists have found evidence to support herbal's wide range of medicinal actions. These actions include the lowering of cholesterol levels, relief for allergies and asthma etc. Herbs have been used by people for longer than we have been keeping written record. Originally they were found in the wild by the gatherers and used for lots of different things. I light here, the use of herbals in asthma. It aims to tap into the body’s own healing mechanism by transforming the “triggers” of such attacks as part of the remedy. Opinions of different authors are saying that herbal medication is better way for asthma treatment.

Indian Drugs and Pharmaceuticals Limited (IDPL) is a Central Public Sector Undertaking wholly owned by the Government of India engaged in manufacture of pharmaceuticals with plants at Rishikesh, Gurgaon & Hyderabad and two Subsidiary Units at Chennai and Muzaffarpur.

The Indian Council of Medical Research (ICMR), New Delhi, the apex body in India for the formulation, coordination and promotion of biomedical research, is one of the oldest medical research bodies in the world.

About Authors:
Gunjan Kalyani^*, Vishal S. Deshmukh, Pranita Kashyap, Yogesh Vaishnav, Ajit Kumar Pandey
Shri Rawatpura Sarkar Institute of Pharmacy,
Kumhari, Durg, Chhattisgarh.
kalyani.gunjan@yahoo.in, rvg_54767@yahoo.co.in*

Abstract:
The IUPAC Name of Salmeterol is (RS)-2-(hydroxymethyl)-4-{1-hydroxy-2-[6-(4-phenylbutoxy) hexylamino]ethyl}phenol. Salmeterol is a prescription drug that is used for treating airway spasms in people with asthma or chronic obstructive pulmonary disease (COPD). By relaxing the muscles around the airways to allow more air into and out of the lungs, the medication can help prevent asthma attacks from occurring.Salmeterol comes in the form of an inhalation powder and is generally used twice a day. Present research work deals with UV spectrophotometric method for the estimation of salmeterol in pure form. For the estimation of salmeterol, solvent system employed was ethanol and wavelength of detection (λ_det) was 252 nm. The linearity was obtained in the range 6 – 14 µg/ml, with a regression coefficient, R²= 0.999. The LOD & LOQ were found to be 4.99 µg/ml and 14.24 µg/ml respectively. Obtained results showed that there is minimum intra day and inter day variation. The developed method was validated and recovery studies were also carried out. Sample recovery using the above method was in good agreement with their respective labeled claims, thus suggesting the validity of the method and non-interference of formulation excipients in the estimation.

About Author:
Mahek Goel
Shri Baba Mastnath Institute of Pharmaceutical Science & Research
Asthal Bohar, Rohtak, Haryana (124001)
mahekgoel10@gmail.com

ABSTRACT
Parenteral drug delivery systems are the preparations that are given other than oral route. (Para-outside, enteric–intestine). Parenteral drug delivery systems are most preferred drug delivery systems as they meet many benefits over other dosage forms in many cases such as unconsciousness, nausea, in emergency clinical episodes. The Parenteral administration route is the most common and efficient for delivery of active drug substances with poor bio-availability and the drugs with a narrow therapeutic index. But parenteral route offers rapid onset of action with rapid declines of systemic drug level. For the sake of effective treatment it is often desirable to maintain systemic drug levels within the therapeutically effective concentration range for as long as treatment calls for. It requires frequent injection, which ultimately leads to patient discomfort. For this reason, drug delivery system which can reduce total number of injection throughout the effective treatment, improve patient compliance as well as pharmacoeconomic. These biodegradable injectable drug delivery system offer attractive opportunities for protein delivery and could possibly extend patent life of protein drugs.Parenteral drug delivery system seeks to optimize therapeutic index by providing immediate drug to the systemic pool in required quantity to treat– cardiac attacks, respiratory attacks. This article explores various prolonged release parenteral drug delivery system and their strategies of preparation, their potential benefits/drawbacks and in-vitro testing methods.