Translational Health Science and Technology Institute (THSTI) is an autonomous Institute of the Department of Biotechnology, Ministry of Science and Technology, Govt, of India. The institute is an integral part of the interdisciplinary NCR Biotech Science Cluster located at Faridabad, and is designed as a dynamic, interactive organization with the mission to conduct innovative translational research and to develop research collaborations across disciplines and professions to translate concepts into tangible products to improve human health.

Post : Research Associate

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ABOUT AUTHORS
R. Mishra¹, P. Barad¹, N. Patel², N. Patel³*
¹Department of Pharmacy,
Shree S.K. Patel College of  Pharmaceutical  Education & Research
Ganpat University, Kherva, Mehasana Gujarat
²Department of Pharmacognosy,
Shree S.K. Patel College of  Pharmaceutical  Education & Research
Ganpat University, Kherva, Mehasana Gujarat
³Department of Pharmacology,
Shree S.K. Patel College of  Pharmaceutical  Education & Research
Ganpat University, Kherva, Mehasana Gujarat

ABSTRACT
Worldwide cancer is the major cause of death. Almost 8.8 million people died due to different types of cancer such as lung cancer, liver cancer, breast cancer, stomach cancer, blood cancer etc. in 2015. Government of various countries and some private organizations are spending trillions dollars for the research in cancer.  According to report of WHO treatment cost of cancer is approximately US$ 1.16 trillion per year and this amount is increasing per year. Despite of huge work the exact cause of genesis is still unknown. Couples of therapies like chemotherapy, radiation, surgery and targeted therapy are available with some detrimental effect. Now scientists are seeking lead molecule from naturally occurring substances due to high safety margin as compared to current approaches. Natural phytochemicals are prominent strategy for prevention, treating, and curing cancer. There are many phytochemicals from herbs having potent anticancer property. Generally these phytochemicals treat cancer by different mechanisms like augmenting apoptosis, cell cycle arrest, targeting to some specific cancer inducing proteins, increasing cytotoxicity etc. This is our little attempt to gather information of phytochemicals having anticancer property such as Etoposide, Curcumin, Vincristine, etc. with postulated mechanism. Etoposide is effective in lung cancer, ovarian cancer by inhibiting type II Topoisomerase. Various research revealed that Curcumin is effective in different types of cancers by increasing apoptosis and targeting specific gene such as MDM2 oncogene is inhibited through the ETS2 transcription factor by modulation of signaling pathway PI3K/mTOR in breast cancer. Vincristine shows anticancer property by oncogenic EWS-FLI1 fusion protein inhibition which cause G2-M phase cell cycle arrest & reduce tumor. This review depicts few phytochemicals having anticancer property such as Etoposide, Curcumin, vincristine, etc. with possible mechanism.

CDRI is considered to be a pioneer research organization in the field of biomedical research where all the infrastructure and expertise are available to develop a drug right from its concept to market. The very latest techniques and methodologies are employed for developing drugs, diagnostics and vaccines to combat diseases prevalent among mankind in general and Indian population in particular. CDRI is a multidisciplinary research laboratory consisting of scientific personnel of various areas of biomedical sciences. For administrative and scientific purposes the Institute's manpower has been grouped into 17 R&D divisions and few divisions providing technical and scientific support.

Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna 800 007, a permanent Institute of Indian Council of Medical Research, Department of Health Research, Ministry of Health & Family Welfare, Govt. of India, invites online applications from suitable candidates for appointment on the Group A Scientific posts as mentioned below.

Teerthanker Mahaveer University is a Jain Minority State Private University established by Act No. 30 of 2008 of the Government of Uttar Pradesh and has been approved by University Grants Commission (UGC) under Section 2(f) of UGC Act, 1956. The university is located on National Highway-24 and is barely 144 Kms from National Capital, New Delhi. The University stand committed to the ideals of Lord Mahaveer i.e. Right Philosophy, Right Knowledge, and Right Conduct in all its operations and aspires to be recognized as an ultimate destination for world-class education.

Post : Professor / Associate Professor / Assistant Professor

Wipro Ltd is a global information technology, consulting and outsourcing company with services spanning financial services, retail, transportation, manufacturing, healthcare services, energy and utilities, technology, telecom and media.  Serving clients in 175+ cities across 6 continents, we help customers do business better by leveraging our industry-wide experience, deep technology expertise, comprehensive portfolio of services and vertically aligned business model. Our 55+ dedicated emerging technologies ‘Centers of Excellence’ enable us to harness the latest technology for delivering business capability to our clients. Wipro also champions optimised utilization of natural resources, capital and talent.

Post : Project Lead - Enterprise Platform Engineering

Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Post : Senior Analyst

This is a question we’ve asked ourselves over and over. It’s how we at Medtronic have made hearts beat stronger and longer. It’s how we’ve pushed the limits of what technology can do in and for the body. It’s how we will continue to alleviate pain, restore health and extend life. Rising costs, an aging population, and the burden of chronic disease impact us all. And no single entity in the healthcare system can solve these challenges alone. That’s why we’re stepping forward. That’s why we’re prepared to put the full power of our technologies, services, resources — and our people — to work with new partners, in new ways, to usher in a new era in healthcare.

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Piramal Enterprises Limited is the flagship company of the Piramal Group.  Starting from the mid-1980s, PEL has shifted its focus from the textiles industry, and established its entrepreneurial credentials in Pharma, Information Management, and Financial Services. It has grown organically and inorganically and often made contrarian business calls.  When Indian pharmaceutical industry was focused on international generics, we invested in domestic formulation businesses.

Post : Packaging Executive

National Institute of Cancer Prevention and Research has a unique approach of amalgamating strong basic, clinical and applied research, involving medical and community practice with an emphasis on early detection, primary and secondary prevention of cancer. The thrust areas of research include the cancer of the uterine cervix, breast and oral cavity.

Walk in Interview for the Positions of Senior Research Fellow (SRF) is being scheduled as per the details, terms & conditions given below against the each project. The candidates are advised to read the advertisement carefully. There are three different projects having the vacant positions.

Institute of Life Sciences (ILS), Bhubaneswar, an autonomous institute of the Department of Biotechnology, Ministry of Science & Technology, Government of India invites applications from Indian Nationals to join in the following position.

Post : Research Associate

The Rajiv Gandhi Centre for Biotechnology (RGCB) is a growing phenomenon. Located in Thiruvananthapuram, the capital city of Kerala, RGCB began in 1990 amongst humble surroundings as a small charitable society called the Centre for Development of Education, Science and Technology (C-DEST). In 1991, recognizing its potential, the C-DEST was made a “Grant-in-Aid” institute of the Government of Kerala and renamed as Rajiv Gandhi Centre for Development of Education, Science and Technology (RGC-DEST), becoming the first institute in the country to be named after Sri Rajiv Gandhi, the young illustrious and visionary former Prime Minster of India.

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ARBRO PHARMACEUTICALS PRIVATE LIMITED, a tested & trusted name in Indian pharmaceutical Industry having more than 25 years of experience in manufacturing and exporting of pharmaceutical formulations , trading of raw materials and Research & Development for pharmaceutical Industry Dedicated to provide best quality products in pharmaceutical, bio-technology & healthcare Industry, Arbro is at paramount & has strong presence in exports, generic formulations, ethical range of tablets.

Post : QC Analyst

Siddhi College of Pharmacy, Pune, Maharashtra invites application for the posts of faculty.

Govt. of Himachal Pradesh took up initiative in early seventies to set up a CSIR lab to make prudential use of the natural resources of the region. After several levels of discussions a formal request was made by then Chief Minister of HP to Vice President, CSIR in 1982 for initiating the matter, and giving final shape to the proposal. The dream of HP government finally came true in 1983 when the foundation stone of this National lab was laid as CSIR Complex Palampur by Prof. Nurul Hasan, former Vice President of CSIR, with then Chief Minister of HP chairing the function.

IQVIA  is The Human Data Science Company focused on using data and science to help healthcare clients find better solutions for their patients. Formed through the merger of IMS Health and Quintiles, IQVIA offers a broad range of solutions that harness advances in healthcare information, technology, analytics and human ingenuity to drive healthcare forward.

Post : Associate Manager, Safety Operations

Thermo Fisher Scientific Inc. is the world leader in serving science, with revenues of more than $20 billion and approximately 70,000 employees globally. Our M​ission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics, deliver medicines to market and increase laboratory productivity. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive services.​

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The main objective of Karnataka State Pharmacy Council is to regulate the professional practice to ensure only qualified registered Pharmacist would enter the profession to provide service to the patient.  The prime responsibility of the Karnataka State Pharmacy Council is to grant registration to the eligible pharmacists and issue Registration certificate to the persons possessing requisite prescribed qualification as per the provisions of section 32(2) of the Pharmacy Act and to enforce the necessary provisions of the Pharmacy Act 1948.

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Broadcast Engineering Consultants India Limited (BECIL) an ISO 9001:2015, ISO 27001:2013 and ISO/IEC 20000:2012 certified, Mini Ratna, Central Public Sector Enterprise of Government of India was established on 24th March 1995. BECIL provides project consultancy services and turnkey solutions encompassing the entire gamut of radio and television broadcast engineering viz; content production facilities, terrestrial transmission facilities, satellite and cable broadcasting facilities in India and abroad. It also provides associated services like building design and construction related to broadcasting, human resource related activities like training and providing man power.

Post : Pharmacist