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Preparation and evaluation of nano-emulsion formulation by using spontaneous emulsification


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January 2017 ARTICLE LIST >>

PharmaTutor (January - 2017)


ISSN: 2347 - 7881
(Volume 5, Issue 1)


Received On: 16/08/2016; Accepted On: 03/09/2016; Published On: 01/01/2017


Deepa Dhiman,* Amit kumar Pal, Aman Mittal, Sunit Saini
Department of Pharmacy,  Smt. Tarawati Institute of Biomedical Allied Sciences, Roorkee



ABSTRACT: The objective of our investigation was to design a thermodynamically stable and dilutable nanoemulsion formulation of Ibuprofen, with minimum surfactant concentration that could improve its solubility, formulation were taken from thermodynamic stability and dispersibility test. The oil, surfactant, co-surfactant and aqueous phase, respectively, containing 100mg of ibuprofen showed a significant improvement in drug release. In vitro drug release of the nanoemulsion formulation was highly significant as compared to marketed tablet formulation. The present study revealed that tinidazole nanoemulsion could be used as a liquid formulation for increase bioavailability. The formulated system can also be treated as self nano emulsifying drug delivery system.



How to cite this article: Dhiman D, Pal AK, Mittal A, Saini S;Preparation and evaluation of nano-emulsion formulation by using spontaneous emulsification; PharmaTutor; 2017; 5(1); 54-58