Articles

  • PharmaTutor
    9 July 2013

    COMPARATIVE STATUS OF OXIDANT/ANTIOXIDANT IN PREGNANCY INDUCED HYPERTENSION AND CERVICAL DYSPLASIA

    About Author:
    *Seema Singh1, Sandeep Kumar Singh2
    1Department of Pharmacy, Northern India Engineering College, Lucknow (U.P.) India
    2Department of Pharmaceuticals Sciences, Dr. H S Guar University Sagar (M.P.), India
    *seema_b.pharm@rediffmail.com

    Abstract:
    Present study is aimed to delineate a co-relation between status of anti-oxidant enzymes, lipid peroxidation products with severity of Pregnancy Induced Hypertension (PIH) and cervical dysplasia. The study has been done on 66 patients out of whom 14 were normal pregnancy and had no disease, 31 patients of PIH and 21 patients having cervical dysplasia gr. I-II. Enzymatic activities of Superoxide dismutase (SOD), Catalase (CAT), vitamin C and vitamin E and malonaldehyde levels (MDA, a marker of lipid peroxides) were assessed spectrophotometrically. Mean Malonaldehyde level in PIH patients (8.48 ± 0.96) & Cervical patients (8.31 ± 1.25) in comparison to normal patients (4.88 ± 1.035), the rise was found highly significant (p < 0.001). The enzymatic activity of antioxidants such as Superoxide dismutase, Catalase, vitamin C and vitamin E was decreased in PIH patients & cervical dysplasia patients as compared to normal patients (p < 0.001). The difference was statistically significant (p < 0.001) whereas the same was observed in cervical dysplasia patients. No statistically difference was observed between the levels of antioxidants of PIH patients & cervical dysplasia patients (p < 0.01). Co-relation of Hb with MDA level showed that aneamic patients have raised level of MDA as compared to non aneamic patients. There is positive oxidant/antioxidant balance which may aggravate free radical damage during pre eclampsia and eclampsia with cervical dysplasia.

  • 9 July 2013
    SINGLE CELL PROTEIN AND BAKER’S YEAST

    ABOUT AUTHOR:
    Rajesh G. Dobariya
    shree M.&N. Virani Science College,
    Rajkot
    drajesh47@gmail.com

    ABSTRACT
    Single cell protein typically refers to source of mixed protein extracted from pure or mixed culture of algae, yeast, fungi or bacteria. The microbes which are used for single cell protein production must be non-pathogenic to plants, animals and man. Good nutritional value, easily and cheaply produced on scale, toxin free, fast growing, easily to separate from the medium and to dry. They have many silent feature. Biomass production is ordinarily carried out in continuous mode to maximize yields and economic scale. The raw material of this process is very cheap because we used molasses, whey, gas, oil etc. For a substrate. So SCP is waste to best. The molasses and various salts including ammonium and phosphate salt contain of the baker’s yeast. The yeast are used for the production of SCP. The baker’s yeast is useful to as and they create disadvantages also the SCP and baker’s yeast very useful for organism.

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  • 8 July 2013
    PERIPHERAL VASCULAR DISEASES: AN UNDERDIAGNOSED CAUSE OF PAIN

    ABOUT AUTHORS:
    Patil Reshma R.*, BhutkarM.A., Gaikwad Pranita T.
    Rajarambapu College of Pharmacy, Kasegaon,
    Maharashtra 415405 India
    *Patil.reshma1990@gmail.com

  • 8 July 2013
    PREPARATION AND CHARACTERIZATION OF FLOATING BIOADHESIVE MICROBEADS OF CLARITHROMYCIN

    About Authors:
    *Shaikh T. K., Jadhav S.L., Gadhave M.V.
    Department of Pharmaceutics,
    VJSM’s Vishal Institute of Pharmaceutical Education and Research, Ale,
    Pune (411412)
    *taiyyab1234@gmail.com

  • 7 July 2013
    INVENTORY MANAGEMENT

    About Authors:
    Madan Gore*, Chetan Galage
    B.Pharmacy, Appasaheb Birnale College of pharmacy,
    Sangli District-Sangli, Maharashtra 416416, India.
    *madan.gore@rediffmail.com

  • 5 July 2013
    HERBAL REMEDIES USED IN THE TREATMENT OF EPILEPSY

    ABOUT AUTHORS:
    Sachchidanand Pathak*, L Singh, T Singh, S K Sharma
    Sunder Deep Pharmacy College,
    Ghaziabad, Uttar Pradesh, India
    sachchidanand.pathak904@gmail.com

    ABSTRACT- 
    This article has been made to review of following plants used for the antiepileptic activity. The plant sources of India are likely to provide effective antiepileptic agents. Herbs have a vital role in the prevention and treatment of convulsion. The phytochemical exploration of these herbs has contributed to some extent in this race for the discovery of new antiepileptic drugs (AED). In recent years owing to the fear of side effects people prefer more and more use of natural plant products for convulsions. This review also helps to summarize the diverse methodologies and ways to evaluate the potential natural compounds having antiepileptic activity.

    Convulsion is the second most common neurologic disorder after stroke. Approximately 1% of the world’s population has convulsion, it is a condition where the patient suffers from recurrent seizures. Control to seizures numerous conventional drugs came into existence. Most of the epileptic patients need polytherapy of conventional anticonvulsants and still not 100% cured.

    The major drawback due to these agents is their chronic side effects and drug interactions which restrict its use. On the other hand nature has provided us plants to be used as natural remedy for diseases with least side effects and insignificant drug interactions. This has motivated the researchers towards herbal remedy for anticonvulsant activity. In this review, herbal drugs have been discussed with more emphasis on the research advancements of traditional or herbal anticonvulsants.

  • 4 July 2013
    REMOTE INTELLIGENT DRUG DELIVERY SYSTEM: A POTENTIAL DEMAND

    ABOUT AUTHORS:
    Nitish Maini*, Saroj Jain, Satish Sardana
    Hindu College of Pharmacy,
    Sonipat, Haryana, India
    *nitishmaini@yahoo.com

    ABSTRACT
    Patients who may otherwise be unable to take medication may benefit from new electronic implants capable of dispensing drugs automatically. The Remote Intelligent Drug Delivery System (RIDDS), a device implanted under the skin and connected to a wireless control center, overcomes the inconvenience associated with taking drugs manually. Such devices include built-in sensors that allow health care workers to monitor pulse rate, blood oxygen levels and other functions. Based on the information, they can adjust how frequently the medication is delivered or increase or decrease amounts as necessary. Nowadays, the Remote Intelligent Drug Delivery System (RIDDS) is a potential demand as they will be especially beneficial for people with physical or mental disabilities, who would otherwise be unable to take medications on their own.

  • 4 July 2013
    A REVIEW ARTICLE ON SYNRIAM INDIAs FIRST ANTI-MALARIAL DRUG

    ABOUT AUTHOR:
    Shikha Patel
    M.pharm (Quality Assurance), Sagar Institute of Research and Technology-Pharmacy
    Bhopal (M.P)
    siyapatel2007@gmail.com

  • 3 July 2013
    REVIEW: REGULATORY PROVISIONS REGARDING COSMETICS IN INDIA

    ABOUT AUTHOR:
    Abhijeet Welankiwar
    Govt. college of Pharmacy,
    kathora naka,
    Amravati (Maharashtra), 444604.
    abhi123welankiwar@gmail.com

    ABSTRACT:
    The Government of India through the Drug and Cosmetic act 1940 and rules 1945 has made stringent provisions regarding import, Manufacturing, Sale and Distribution of Cosmetics. These provisions mainly cover the licensing for the import, manufacturing of cosmetics and also the GMPs for the manufacturing of cosmetics. Also these guidelines have covered certain categories of cosmetics whose import and sale is prohibited by the Law. These guidelines have also listed the 28 cosmetics whose import is allowed only on to the conformance to the Indian standards. These guidelines have also covered the offences and penalties in case of contravention of the provisions of the Drug and Cosmetic Act 1940.

  • 3 July 2013
    ANALYTICAL METHOD DEVELOPMENT & VALIDATION FOR ESTIMATION OF TERAZOSIN HYDROCHLORIDE EQUIVALENT TO TERAZOSIN IN TABLET DOSAGE FORM

    ABOUT AUTHORS:
    Ritobrata Rudra*1, Sudipta Ganguly2, Manabendra Dhua3, Binny sikdar4
    1Department of pharmaceutical chemistry, Gupta College of Technological Sciences, Asansol.
    2Department of Quality control, Stadmed pharmaceutical pvt ltd, Dumdum, Kolkata.

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