PHARMACOLOGICAL EVALUATION OF STEM BARK EXTRACT OF JATROPHA CURCAS L. FOR ANTI-DIABETIC ACTIVITY
About Authors:Kamal Sachdeva*2, Preeti Garg1, Manmohan Singhal2, Birendra Srivastava2
1. School of Pharmacy, Suresh Gyan vihar University, Jaipur
2. School of Pharmaceutical sciences,
Jaipur National University,
Jaipur, India
Abstract: The extracts of the stem bark of Jatropha curcas (Family-Euphorbiaceae) were tested for anti-diabetic activity, using blood glucose level in normal fasted rats, glucose tolerance test. Methanol: acetone: water (70:20:10) crude extract of Jatropha curcas at the dose of 100 and 300 mg/kg had shown significant protection and lowered the blood glucose levels to normal in glucose tolerance test. The extract showed a significant anti- diabetic activity comparable with that of glibenclamide. These results indicate that the Jatropha curcas stem bark possess significant anti – diabetic activity.