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  • Baumans, V., 2004. Use of animals in experimental research: an ethical dilemma? Gene Therapy. 11(Suppl 1), S64-S66.
  • Berube, K.A., 2011. Alternatives for lung research, stuck between a rat and a hard place. Alternatives to Laboratory Animals.39(2), 121-130.
  • Breckenridge, R., 2010. Heart failure and mouse models. Disease Model and Mechanism. 3(3-4), 138-143.
  • Castren, E., Elgersma, Y., Maffei, L., Hagerman, R., 2012. Treatment of neurodevelopmental disorder in adulthood.Journal of Neuroscience.32(41), 14074-14079.
  • Chen, C.A., Carolan, P.C., Annes, J.P., 2012. In-vivo screening for secreted proteins that modulate glucose handling identifies interleukin-6 family members as potent hypoglycemic agents. PLoS One. 7(9), e44600.
  • Cui, H., Lee, J.H., Kim, J.Y., Koo, B.N., Lee, J.E., 2012. The neuroprotective effect of agmatine after focal cerebral ischemia in diabetic rats.Journal of Neurosurgical Anaesthesiology.24(1), 39-50.
  • DiCarlo, A.L., Jackson, I.L., Shah, J.R., Czarniecki, C.W., Maidment, B.W., Williams, J.P., 2012. Development and licensure of medical countermeasures to treat lung damage resulting from a radiological or nuclear incident. Radiation Research.177(5), 717-721.
  • Feng, J., Wang, T., Li, Q., Wu, X., Qin, X., 2012. RNA interference against repulsive guidance molecule A improves axon sprout and neural function recovery of rats after MCAO/reperfusion. Experimental Neurology. 238(2), 235-242.
  • Fischer, M., Koch, W., Windt, H., Dasenbrock, C., 2012. A pilot study on the refinement of acute inhalation toxicity studies, the isolated perfused rat lung as a screening tool for surface-active substances. Alternative to Laboratory Animals.40(4), 199-209.
  • Fujimoto, J., Kadara, H., Men, T., van Pelt, C., Lotan, D., Lotan, R., 2010. Comparative functional genomics analysis of NNK tobacco-carcinogen induced lung adenocarcinoma development in Gprc5a-knockout mice. PLoS One. 5(7), e11847.
  • Galdino, P.M., Nascimento, M.V., Florentino, I.F., Lino, R.C., Fajemiroye, J.O., Chaibub, B.A., de Paula, J.R., de Lima, T.C., Costa, E.A., 2012. The anxiolytic-like effect of an essential oil derived from Spiranthera odoratissima A. St. Hil. leaves and its major component, β-caryophyllene, in male mice.Progress in Neuro-psychopharmacology & Biological Psychiatry.38(2), 276-284.
  • Glass, J.D., Fedor, H., Wesselingh, S.L., McArthur, J.C., 1995. Immunocytochemical quantization of human immunodeficiency virus in the brain, correlations with dementia.Annals of Neurology.38, 755-762.
  • Hasebe, M., Matsumoto, I., Imagawa, T., Uehara, M., 2008.Effects of an anti-thyroid drug, methimazole, administration to rat dams on the cerebellar cortex development in their pups.International Journal of Developmental Neuroscience.26(5), 409-414.
  • Haughey, N. J., Mattson, M. P., 2002. Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120.Journal of Acquired Immunodeficiency Syndrome. 31 Suppl 2, S55-61.
  • Hellström, P. M., 2009. GLP-1, broadening the incretin concept to involve gut motility. Regulatory Peptides. 156(1-3), 9-12.
  • Hirai, T., Enomoto, M., Machida, A., Yamamoto, M., Kuwahara, H., Tajiri, M., Hirai, Y., Sotome, S., Mizusawa, H., Shinomiya, K., Okawa, A., Yokota, T., 2012.Intrathecal shRNA-AAV9 inhibits target protein expression in the spinal cord and dorsal root ganglia of adult mice. Human Gene Therapy Model.23(2), 119-127.
  • Hwang, H.S., Han, K.J., Ryu, Y.H., Yang, E.J., Kim, Y.S., Jeong, S.Y., Lee, Y.S., Lee, M.S., Koo, S. T., Choi, S. M., 2009. Protective effects of electroacupuncture on acetylsalicylic acid-induced acute gastritis in rats.Journal of Gasteroenterology.15(8), 973-977.
  • Kaul, M., 2008.HIV’s double strike at the brain, neuronal toxicity and compromised neurogenesis.Frontierin Bioscience.13, 2484-2494.
  • Kramer-Hämmerle, S., Rothenaigner, I., Wolff, H., Bell, J.E., Brack-Werner, R., 2005. Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus.Virus Research. 111(2), 194-213.
  • Kumar, V., Singh, P.N., Mishra, B., 2000. Animal experimentation: A rational approach towards drug development. Indian Journal of Experimental Biology.38, 540-548.
  • Lee, J., Li, M., Milwid, J., Dunham, J., Vinegoni, C., Gorbatov, R., Iwamoto, Y., Wang, F., Shen, K., Hatfield, K., Enger, M., Shafiee, S., McCormack, E., Ebert, B.L., Weissleder, R., Yarmush, M.R., Parekkadan, B., 2012. Implantable microenvironments to attract hematopoietic stem/cancer cells.Proceedings of the National Academy of Sciences of The United States of America.109(48), 19638-19643.
  • Li, Q.Z., Kong, L.F., Zhang, S.N., Zhong, Z.S., Zhang, B.H., Liu, X.F., 2009. The expression of substance P in airway mucosa of guinea pigs with repetitive esophageal stimulation by hydrochloric acid.Chinese Journal of Tuberculosis and Respiratory Diseases.32(6), 426-429.
  • Lipton, S.A., 1991. HIV-related neurotoxicity. Brain Pathology. 1(3), 193-199.
  • Lipton, S.A., 1994. Neuronal injury associated with HIV-1 and potential treatment with calcium-channel and NMDA antagonists. Developmental Neuroscience. 16(3-4), 145-151.
  • Mifune, H., Nishi, Y., Tajiri, Y., Masuyama, T., Hosoda, H., Kangawa, K., Kojima, M., 2012. Increased production of active ghrelin is relevant to hyperphagia in nonobese spontaneously diabetic Torii rats. Metabolism, Clinical and Experimental.61(4), 491-495.
  • Mittal, N., Kanwar, S.S., Sanyal, S.N., 2008. Effect of non-steroidal anti-inflammatory drugs and the pro-carcinogen 1,2 dimethylhydrazine on the rat intestinal membrane structure and function.NutricionHospitalaria. 23(5), 439-448.
  • Muley, M.M., Thakare,V.N., Patil, R.R., Kshirsagar, A.D., Naik, S.R., 2012. Silymarin improves the behavioural, biochemical and histoarchitecture alterations in focal ischemic rats, a comparative evaluation with piracetam and protocatachuic acid. Pharmacology Biochemistry and Behavior. 102(2), 286-293.
  • Nordquist, N., Luthman, H., Pettersson, U., Eriksson,U.J., 2012. Linkage study of embryopathy-polygenic inheritance of diabetes-induced skeletal malformations in the rat. Reproductive Toxicology. 33(3), 297-307.
  • Okuma, Y., Liu, K., Wake, H., Zhang, J., Maruo, T., Date, I., Yoshino, T., Ohtsuka, A., Otani, N., Tomura, S., Shima, K., Yamamoto, Y., Yamamoto, H., Takahashi, H.K., Mori, S., Nishibori, M., 2012. Anti-high mobility group box-1 antibody therapy for traumatic brain injury.Annals of Neurology.72(3), 373-384.
  • Otto, P.H., Clarke, I.N., Lambden, P.R., Salim, O., Reetz, J., Liebler-Tenorio, E.M., 2011. Infection of calves with bovine norovirus GIII.1 strain Jena virus, an experimental model to study the pathogenesis of norovirus infection. Journal of Virology.85(22), 12013-12021.
  • Phillips, J., Moore-Medlin, T., Sonavane, K., Ekshyyan, O., McLarty, J., Nathan, C.A., 2013.Curcumin Inhibits UV Radiation-Induced Skin Cancer in SKH-1 Mice.OtolaryngolHead and Neck Surgery. 148(5), 797-803.
  • Pratte, M., Panayotis, N.,Ghata, A., Villard, L., Roux, J.C., 2011.Progressive motor and respiratory metabolism deficits in post-weaning Mecp2-null male mice.Behavioral Brain Research.216(1), 313-320.
  • Redmond, Jr., D.E., 2012. Using Monkeys to Understand and Cure Parkinson Disease. HastingsCenter Report.42, S7-S11.
  • Research Defence Society & Coalition for Medical Progress, 2007. Medical advances and animal research.Published byRDS: Understanding Animal Research in Medicine and Coalition for Medical Progress.
  • Robertson, J.H., Yang, S.Y., Iga, A.M., Seifalian, A.M., Winslet, M.C., 2008. An in-vivo rat model for early development of colorectal cancer metastasis to liver.International Journal of Experimental Pathology.89(6), 447-457.
  • Robinson, L., Guy, J., McKay, L., Brockett, E., Spike, R.C., Selfridge, J., De Sousa, D., Merusi, C., Riedel, G., Bird, A., Cobb, S.R., 2012. Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome. Brain. 135(Pt 9), 2699-2710.
  • Rowan, A.N., 1997.The benefits and ethics of animal research. Scientific American. 276(2), 79-93.
  • Sahni, S.K., 2000. Guideline for care and use of animals in Scientific Research. Indian National Science Academy, First Edition (Revised). New Delhi.
  • Saini, R., Sorace, A.G., Warram, J.M., Mahoney, M.J., Zinn, K.R., Hoyt, K., 2013. An animal model allowing controlled receptor expression for molecular ultrasound imaging. Ultrasound in Medicine and Biology.39(1), 172-180.
  • Schmid, A., Rignall, B., Pichler, B.J., Schwarz, M., 2012. Quantitative analysis of the growth kinetics of chemically induced mouse liver tumors by magnetic resonance imaging. Toxicological Sciences. 126(1), 52-59.
  • Sheth, R.A., Josephson, L., Mahmood, U., 2009. Evaluation and clinically relevant applications of a fluorescent imaging analog to fluorodeoxyglucose positron emission tomography.Journal of Biomedical Optics.14(6), 064014.
  • Silva, F.G., Penido, L.C., Valente, F.X., Mendes, M.C., Rosa, D.D., Gloria, M.B., PeluzioMdo, C., 2010. Sodium butyrate does not decrease the evolution of precancerous lesions in rats.ActaCirurgicaCrasileira. 25(6), 507-512.
  • Sontag, E.M., Lotz, G.P., Agrawal, N., Tran, A., Aron, R., Yang, G., Necula, M., Lau, A., Finkbeiner, S., Glabe, C., Marsh, J.L., Muchowski, P.J., Thompson, L.M., 2012.Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models. Journal of Neurosciences.32(32), 11109-11119.
  • Tesla, R., Wolf, H.P., Xu, P., Drawbridge, J., Estill, S. J., Huntington, P., McDaniel, L., Knobbe, W., Burket, A., Tran, S., Starwalt, R., Morlock, L., Naidoo, J., Williams, N. S., Ready, J.M., McKnight, S. L., Pieper, A. A., 2012. Neuroprotective efficacy of aminopropylcarbazoles in a mouse model of amyotrophic lateral sclerosis.Proccedings of the National Academy of Sciences of the United States of America.109(42), 17016-17021.
  • Truong, D.T., Venna, V.R., McCullough, L.D., Fitch, R.H., 2012.Deficits in auditory, cognitive, and motor processing following reversible middle cerebral artery occlusion in mice. Experimental Neurology. 238(2), 114-121.
  • Van Hoecke, A., Schoonaert, L., Lemmens, R., Timmers, M., Staats, K.A., Laird, A.S., Peeters, E., Philips, T., Goris, A., Dubois, B., Andersen, P.M., Al-Chalabi, A., Thijs, V., Turnley, A.M., van Vught, P.W., Veldink, J.H., Hardiman, O., Van Den Bosch, L., Gonzalez-Perez, P., Van Damme, P., Brown, R.H., Jr, van den Berg, L.H., Robberecht, W., 2012. EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nature Medicine. 18 (9), 1418-1422.
  • Wang, I.F., Guo, B.S., Liu, Y.C., Wu, C.C., Yang, C.H., Tsai, K.J., Shen, C.K., 2012. Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43. Proceedings of the National Academy of Sciences of the United States of America.109 (37), 15024-15029.
  • Wiley, C.A., Masliah, E., Achim, C.L., 1994.Measurement of CNS HIV burden and its association with neurologic damage. Advanced Neuroimmunology. 4, 319-325.


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