Articles

REVIEW ON MOISTURE ACTIVATED DRY GRANULATION PROCESS

ABOUT AUHTORS
Devender M. Sharma*1, Satish B. Kosalge1, Swati N. Lade1
Hi – Tech college of pharmacy, Chandrapur (M.S.)

*sdevender350@gmail.com

ABSTRACT
Tablets are unit solid dosage form of medicament which largely used to compare other dosage form of medicaments. In tablet manufacturing, wet granulation and dry granulation methods largely used as compare to MADG process. In wet granulation and dry granulation methods various steps has been carried out like dispensing and shifting, dry mixing, granulation, pre-drying, shifting, premixing, lubrication and compression. But in MADG process, escape various steps like slugging, pre- drying, shifting, and drying. Hereby in MADG process save energy, cost of product and time also. The main object of review is hereby moisture activated dry granulation process very beneficial in case of water insoluble drug and water poorly soluble drug other than granulation method like wet granulation. Another objective of review how moisture activated dry granulation process carried out and given various advantages over the other granulation method. In water insoluble drug case MADG process largely used and very useful method for pharmaceutical industries.


EXTRACTION AND CHEMICAL TESTS ON Nigella sativa L. COLLECTED FROM PUNJAB REGION OF INDIA

ABOUT AUHTOR
Saptarshi Samajdar
Centre for Pharmaceutical Sc. And Natural Products, Central University of Punjab

*saptarshisamajdar20@gmail.com

ABSTRACT: Nigella sativa is a wonder plant which has the potential to cure almost all diseases except death. The medicinal value of the plant has been reported quite long ago and finds its place in Holy Quran. Nigella Sativa of Family Ranunculaceae contains chemical components like Thymoquinone, alpha hederin which are anticancer in nature. So in this article emphasis on the different solvent extraction and its chemical tests have been shown from the seeds collected from Punjab, India.


PHYTOFABRICATION FOR THE SYNTHESIS OF NANOPARTICLES - REVIEW

ABOUT AUHTORS
*R.Karthikeyan, E.Meghana, N.Gowthami, MD.Shajiya sultana, B.Mahesh reddy, SK.Magbul Johny, P.Srinivasa Babu
Department of Pharmacognosy, Vignan Pharmacy College, Vadlamudi – 522213.A.P
*rkcognosy@gmail.com

ABSTRACT
The synthesis of nanostructure substances, specifically metal nanoparticles, has accrued utmost concern over the last decade owing to their particular properties that cause them to applicable in distinctive fields of technology era. The biological technique of nanoparticle synthesis is a relatively easy, reasonably-priced, and environmental friendly approaches than the conventional chemical technique of synthesis and accordingly profits a top hand. The bio mineralization of nanoparticles in protein cages is one among such biological approaches used inside the era of nanoparticles. In this review we attempted to explore different techniques of synthesis of nanoparticles and its characterization. Further this review extended the usage of such nanoparticle in different fields.


AN OVERVIEW ON POLYMERIC NANOPARTICLESUSED IN THE TREATMENT OF DIABETES MELLITUS

ABOUT AUHTORS
K.GOPALASATHEESKUMAR1*, S.KOMALA2 AND M.MAHALAKSHMI2
1KMCH college of Pharmacy, Kovai Estate, Kalapatti Road, Coimbatore-641048, Tamil Nadu, India.
2Jaya College of Paramedical sciences, College of Pharmacy, Thiruninravur, Chennai – 602024, Tamil Nadu, India.
*gskpungai@gmail.com

ABSTRACT 
The review was carried out to discuss in detail about the polymeric nanoparticles for diabetic treatment. The diabetes is the chronic metabolic disorder characterized by the deficiency of insulin production. The various treatments are available for the diabetes and the nanoparticles are having the several advantages. The various types of nanoparticles are available for the anti-diabetic drugs; the polymeric nanoparticles are the one of the most commonly used nanoparticles. The polymeric nanoparticles are commonly 10-1000nm in size. The polymeric nanoparticles are formulated by drug with the polymers. The main advantages of the polymeric nanoparticles are the simplest preparation method, targeted delivery, the minimizing of the dose and high therapeutic efficiency. In this review was mainly can be focused on advantages, disadvantages of polymeric nanoparticles, various polymers, various formulation techniques, diabetes disease profile, insulin production, various anti-diabetic drugs and the polymeric nanoparticle formulation of anti-diabetic drugs.


FORMULATION, EVALUATION AND VALIDATION OF ORALLY DISINTEGRATING RIZATRIPTAN BENZOATE TABLET

ABOUT AUHTOR
Ms. Sapna
Department of Pharmaceutical Sciences
Himalayan Institute of Pharmacy and Research Rajawala, Dehradun
*bhandarisapna747@gmail.com

ABSTRACT: The present investigation deals with development of orally disintegrating tablets of Rizatriptan Benzoate to produce the intended benefits. Orally disintegrating tablets of Rizatriptan Benzoate were prepared by wet granulation method to provide faster relief from pain to migraine sufferers. Formulation research is oriented towards safety, efficacy and quick onset of action of existing drug molecule through novel concept of drug delivery. About four formulations for the present study were carried out full factorial design. Kyron 314 was used as super disintegrants, while microcrystalline cellulose and mannitol was used as diluents. Starch was used as binder. The prepared batches of tablets were evaluated for weight variation, hardness, friability, wetting time, drug content and in-vitro dissolution studies. The optimized formulation dispersed in within 15 seconds. It also showed a higher water absorption ratio and 99.67% of drug is released within a minute.


LIFE SAVING BINDI A NOVEL APPROACH TO COMBAT IODINE DEFICIENCY

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D. Giri Raja Sekhar*, D. Sai Sravani, H. Thulasi , Chakka  Gopinath
Department of Pharmacy Practice, Annamacharya college of Pharmacy, Rajampet
*giriraj.pharma@gmail.com

ABSTRACT: 
The thyroid gland produces thyroid hormones. The two most important hormones are tetraiodothyronine (thyroxine or T4) and triiodothyronine (T3).Iodine deficiency is a major health problem in India. Iodine deficiency that can lead to disorders like goiter, hypothyroidism and even brain damage. Even mild iodine deficiency in pregnant women can result in children being born with cretinism and mental retardation. The most popular method of tackling the problem has been to encourage the consumption of iodised salt. An iodine patch, designed like a regular bindi, is expected to help iodine deficiency. It seems like a brilliantly simply idea The wearing of bindis form part of a cultural practice of Indian Women, which are “self-adhesive” in between their eyebrows, have been impregnated with a solution of iodine.  Production costs are minimal, wearing the iodine-infused bindi requires no behavioral change.


INFLUENCE OF GDF-11 IN AGING PROCESS : AN REVIEW

ABOUT AUHTORS
Devender Sharma*,  Dr. Satish Kosalge1, Snehal R. Dixit1
Hi – Tech college of pharmacy, Chandrapur (M.S.)
*sdevender350@gmail.com

ABSTRACT:
Aging is one of the phases of individual’s life span, which everyone wants to escape. The process of aging is much more a social phenomena than biological phenomena. Aging brings many changes such as, loss of eyesight, hearing loss, dementia, etc. Aging may give rise to diseased states such as, heart disease, cancer, cerebrovascular disease (relating to blood vessels that supply the brain), pneumonia and flu, and chronic obstructive pulmonary diseases. The key-factor behind aging is the GDF11, i.e., Growth and Differentiation factor-11. GDF11 is also known as Bone Morphogenetic Factor-11 (BMP11). It is termed as key circulating ‘anti-aging’ factor. GDF11 is expressed in wide range of tissues and has been shown to play important roles in development of olfactory system, retina and pancreas. It functions in regulating anterior-posterior patterning of the axial skeleton muscle system. Scientists theorize that aging likely results from a combination of many factors viz., Lifestyle, Diseases and Genes. GDF11 is essential for mammalian development and has been suggested to regulate aging of multiple tissues, whereas myostatin is a well-described negative regulator of postnatal skeletal and cardiac muscle mass and modulates metabolic processes .


A REVIEW ON FORENSIC ANALYTICAL CHEMISTRY

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Manimala M*1, Vijay Kumar D1
Santhi ram College of Pharmacy- Kurnool-Andhra Pradesh
*manimala.mosey@gmail.com

ABSTRACT:
The word “forensic” means “pertaining to the law”; forensic science resolves legal issues by applying scientific principles to them. Forensic Analysis is the application of Analysis to law enforcement or the failure of products or processes. It is unique among chemical sciences in that its research, practice, and presentation must meet the needs of both the scientific and the legal communities.Forensic Analysis applied the basic theory and mythology of advanced analytical chemistry to rationalize various materials of crimes and provide evidence to detection.Forensic Analysis is carried out by the two types of techniques namely Organic Analytical Technique &In- Organic Analytical Technique. And this review article covers regarding how Analytical techniques are useful in forensic analysis to resolve major problems of common man.


CURCUMIN NANO DRUG DELIVERY SYSTEMS: A REVIEW ON ITS TYPE AND THERAPEUTIC APPLICATION

ABOUT AUHTOR
S. Dhivya*, DR. A. N. Rajalakshmi
Department of Pharmaceutics,
Mother Theresa Post Graduate and Research Institute of Health Sciences,
Gorimedu, Puducherry, India

*dhivyaraji310@gmail.com

ABSTRACT: Design and development of herbal nanoparticles has become a frontier research in the nanoformulation arena. Curcumin, a hydrophobic polyphenol (diferuloyl methane) is a potent phytomolecule obtained from turmeric (Curcuma longa, Family-Zingiberaceae) has a wide range of biological activities in chronic diseases and has wide therapeutic efficacy. But the clinical application of curcumin was limited due to its poor water solubility, rapid metabolism and rapid elimination which ultimately results in poor bioavailability upon oral administration. Therefore introduction of nanotechnology provides a solution towards increased bioavailability of curcumin. In this review, an overview of curcumin nanoparticles is discussed.


A STUDY ON ROLE OF DOCTOR OF PHARMACY IN IDENTIFYING AND REPORTING OF DRUG RELATED PROBLEMS AND ITS COMORBIDITIES IN INPATIENT UNITS OF A TERITARY CARE TEACHING HOSPITAL

ABOUT AUHTORS
M. Manasa Rekha*,
Department of Pharmacy Practice,
Annamacharya college of Pharmacy,
Rajampet, Andhra Pradesh,  India.
*manasarekharoyal@gmail.com

ABSTRACT: AIM: The study aims to assess the role of DOCTOR OF PHARMACY in identifying drug related problems in inpatient units in a tertiary care teaching hospital. OBJECTIVES: The main objective of the present study includes identification and reporting of drug related problems like Drug-drug interaction, Adverse drug reactions, Drug use without indication, Therapeutic duplication, Allergy/intolerance/poisoning, Improper drug, dose, route, regimen, Awareness/adherence problems.


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