January 2019

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ABOUT AUTHORS
A. PADMA¹*, D. GIRIJA², A. THIRUPATHIREDDY³, B. VENKATESWARAREDDY^4
1Department of Pharmaceutical Analysis, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam (Dist) Andhra Pradesh, India
²Department of Pharmaceutical Analysis, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam (Dist) Andhra Pradesh, India
³Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M),Prakasam(Dist) Andhra Pradesh, India
⁴Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andhra Pradesh, India

ABSTRACT
The present research work deals with the development  and validation of  stability indicating RP-HPLC method for the simultaneous estimation of Aceclofenac and Drotaverin.HCl in bulk and formulation. Chromatographic separation was achieved on ODS HG-5 RP   C18(250 X 4.6 mm, 5 µm) using the mobile phase consisting of Acetonitrile and1% triethylamine (TEA) in the ratio of 90:10 pH  2.16 adjusted with Ortho phosphoric acid. The mobile phase was pumped at a flow rate of 1.0 mL/min and UV detection was observed  at 224 nm. The retention time was found to be 3.57 min for Aceclofenac and 6.15 min for Drotaverin.HCl. The linearity concentrations are obtained from in the range of 30-70 µg/ml for Aceclofenac and 24-56 µg/ml for Drotaverin.HCl respectively with correlation coefficient was 0.999 and 0.998. The proposed method was found to be simple, accurate, precise and reproducible and developed method can be suggest to routine quality control analysis for simultaneous estimation of Aceclofenac and Drotaverin.HCl in pharmaceutical dosage forms.

Walk-In-Interview will be conducted as scheduled below for filling up the following posts under Rastriya Bal Swasthya Karyakram (RBSK) National Health Mission, Koraput on contractual basis for a period of 11 months with monthly remuneration as noted against each and subject to renewal as per OSH&FW Society terms and conditions.

Post : Pharmacist, RBSK

Rungta College of Pharmaceutical Sciences and Research (RCPSR), Bhilai, managed by GDR Educational Society has been started in 2006.  It is affiliated to Chhattisgarh Swami Vivekanand Technical University (CSVTU), Bhilai, and approved by PCI and AICTE. The courses offered by the institute include D. Pharm., B. Pharm., and M. Pharm. The institute is also an approved Research Center by the CSVTU. RCPSR has recently been accredited by NBA (UG programme) and NAAC. The GDR Educational Society received prestigious SIRO recognition by DSIR. Very recently, the institute received DST FIST grant.

Post : Assistant Professor / Associate Professor

The Birla Institute of Technology and Science, Pilani (BITS Pilani) is an all-India Institute for higher education. Founded in 1964 in collaboration with Massachusetts Institute of Technology (MIT), USA, it is one of the top most educational Institute in India.  The institute is one among the 6 Indian 'Institutes of Eminence' recognized by the Government of India in 2018. It is established across 4 campuses and has 15 academic departments. The BITS, Pilani - K. K. Birla Goa Campus, is about 10 kms south of Vasco-da-Gama, 20 kms north of Margaon and 7 kms east of Goa Airport, along National Highway – 17B, Bypass road.

Post : Junior Research Fellow