September 2012

The PGIMER owes its inception to the vision of late Sardar Partap Singh Kairon, the then Chief Minister of Punjab and the distinguished medical educationists of the then combined state of Punjab, supported by the first Prime Minister of India Pt.

Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.

Our Client is a reputed MNC requires freshers (B.Sc/B.Pharma/D.Pharma) as Medical Representatives for Chennai H.Q.

Post: Medical Representative

About Authors:
Ms.Pratibha Chohan*, Mr.Prashant Mutha
B.Pharmacy, G. D. Memorial College of Pharmacy, Jodhpur.
*pmuthabiotech@gmail.com

ABSTRACT:
Brain is tightly segregated from the circulating blood by a unique membranous barrier, the blood – brain barrier (BBB). Many pharmaceuticals cannot be efficiently delivered to, or sustained within the brain; hence they are ineffective in treating a plethora of cerebral diseases. Therefore, drug delivery methods that can provide drug delivery to brain or eventually preferential brain delivery (i.e. brain targeting) are of particular interest. One technique that holds promise for bypassing the BBB to deliver drugs to the brain and eliminating the surgical risk and the spillover effect of drug to normal tissue is the intranasal delivery.

Applications on the prescribed Proforma, in sealed covers, are invited for the following posts under the Government of Himachal Pradesh so as to reach the Secretary, Himachal Pradesh Subordinate Services Selection Board, Hamirpur (Himachal Pradesh) PIN-177001 on or before 15.10.2012.

Indian Institute of Technology Roorkee, Roorkee invites the applications on the prescribed form for the following posts as per details given against each.

About Authors:
AMOL D.GHOLAP^*1, DATTATRAY TUPE^2
1Department of Pharmaceutics, Vamanrao Ithape D. Pharmacy College,
Velhale, Tal- Sangamner, Dist- Ahmednagar, MS-422605, India.
²Department of Regulatory Affairs, Lupin Limited,
Kalina, Santakruz (E), Mumbai, MS, India-400098.
*amolgholap16@yahoo.com

Abstract
The several evolutions in the field of medicine develop different cellular mechanisms for striking along with entering the target cells with efficiency. The utilization of recombinenet adenovirus as carriers for cDNA induces dose along with therapy limiting of defense mechanisms. Artificial viral envelopes (AVE) are lipid vesicles which mimic with fusogenic envelop of retrovirus to utilize as target selectivity along with efficiency of delivery of viruses. The major component of AVE includes phosphatidylcholine, phosphatidyiserine along with sphingomyelins. The negative charge is present on AVE’s help them for targeting the moieties such as viral binding proteins. The artificial viral envelopes show potential applications in plasmid delivery.