November 2009

 C. binding of drug to tissue component

1. Binding of drug to blood/ plasma protein

Plasma protein binding

                A. Tissue permeability of DRUG
 

1. Physico chemical Properties

            Factors affecting distribution of drug
 

• Tissue permeability of DRUG
  1. Physico chemical Property

                        DISTRIBUTION OF DRUG

                             Physiological factors

                                 Dosage form

                             Physical Properties

   Factors affecting absorption and Bio-availability

A) Physical properties