Telangana

Unity College of Pharmacy & P.G. College

Post: Professors/ Associate Professors/ Assistant Professors

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ABOUT AUTHORS:
Suresh VV Babu¹, Talasila EGK Murthy²*, Chimakurthy Jithendra^3
1Dept. of Pharmaceutics, Natco Pharma Limited, Hyderabad, Telangana, India.
²Dept. of Pharmaceutics, Bapatla College of Pharmacy, Bapatla, Andhra Pradesh, India.
³Dept. of Pharmacology, Bapatla College of Pharmacy, Bapatla, Andhra Pradesh, India.
*drgkm@bcop.net

ABSTRACT
The present study was to assess the relative bioavailability and pharmacokinetic properties of extended release formulations of Ranolazine 1000 mg in healthy male volunteers usinga randomized, open-label, balanced, two-treatment, two-period, two sequence, single dose, crossover, bioequivalence study under fasting conditions. Bioavailability of the test product of Ranolazine extended release tablets 1000 mg was compared with that of the reference product of Ranexa® (Ranolazine extended release tablets 1000mg) of CV Therapeutics Inc., California. The plasma samples were collected at 0.50, 1.00, 1.50, 2.00, 2.50, 3.00, 3.50, 4.00, 4.50, 5.00, 5.50, 6.00, 6.50, 7.00, 8.00, 10.00, 12.00, 16.00, 24.00 and 48.00 hours post dose after single administration of Ranolazine 1000mg. The plasma Ranolazine concentrations were estimated by using a validated bioanalytical method by LC-MS/MS. A ten day washout period is followed between two treatments. The formulations were considered to be bioequivalent if the 90% CIs for the log-transformed values were within the predetermined equivalence range 80%–125% for AUC and C_max. For Ranolazine, at 90% confidence intervals C_max, AUC_0-tand AUC _0-∞ were 83.43-113.29, 82.10-102.87 and 80.94-101.85 for log-transformed data respectively.The present results show that the formulation of Ranolazine was bioequivalent to the reference in fasting, healthy, male volunteers.

ABOUT THE CONFERENCE

Arya Group was established under the aegis of All India Arya Samajis Society of Higher & Technology Education in the year 1999 by the founder chairman Er. Shri T.K. Agarwal, a great visionary, who built the entire edifec Arya Group of Colleges. Globally accepted as a vibrant seat of academic ad professional excellence Arya Group of Colleges is known for its innovative approach, participative culture and academic rigor.

Applications are invited from the eligible candidates for the position of Principal, Professor, Assoc. Professor, Asst. Professor

MedTek.Net is one of the leading Healthcare BPO providers in India. Medtek.net is 14+ years old company. Medtek.net is subsidiary of Medtek.net Inc, California, USA.We provide Medical Transcription and Medical Coding services to several Healthcare Providers and Organizations in USA. We are operating from Ameerpet and Tarnaka in Hyderabad. We also have a branch in Vijayawada.

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A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

Post: Sr. Pharmaceutical Scientist I

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ABOUT AUTHORS:
Jiguru Prasant*, Mohammad Kaleemullah Quraishi, Amer Khan
Department of Doctor of Pharmacy,
Krishna Institute of Medical Sciences and Bharat Institute of Technology (Pharmacy),
Hyderabad, Telangana, India
Prashant7792@gmail.com

ABSTRACT
A 65 yrs female patient was presented with  complaints of vomiting,  loose stools, pain,  fever, high grade chills,  giddiness, loss of appetite acute renal failure, hemolytic anemia and thrombocytopenia She was diagnosed with Escherichia coli  associated hemolytic-uremic syndrome and treated with plasmapheresis and other medications for 3 weeks. She recovered without sequelae.

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A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

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Situated in the heart of the city at Kukatpally a major landmark- Jawaharlal Nehru Technological University, Hyderabad has an environment of academic excellence with ‘A’ Grade accreditation by NAAC (National Assessment and Accreditation Council). Bringing the spark of knowledge to young minds and instilling a new confidence and vigour to face the world,it is providing quality education for nearly 4 decades.