Solan

Dabur India Limited is a leading Indian consumer goods company with interests in Hair Care, Oral Care, Health Care, Skin Care, Home Care and Foods. From its humble beginnings in the bylanes of Calcutta way back in 1884 as an Ayurvedic medicines company, Dabur India Ltd has come a long way today to become a leading consumer products manufacturer in India. For the past 125 years, we have been dedicated to providing nature-based solutions for a healthy and holistic lifestyle.

About Authors:
Shashi Kant^*,  Dr. Bharat Prashar
Department of Pharmaceutical Sciences,
Manav Bharti University,
Solan (H.P)
*shashi_ranaute@yahoo.in

ABSTRACT:
In this review article, we discussed abouteffluent testing and treatment in pharmaceutical industry,Biological treatment of wastewater is frequently the most beneficial method for selecting various toxic compounds from the environment. Most of the organic compounds in industrial wastewaters are of natural origin and can be degraded by common bacteria in aerobic or anaerobic processes. The composition of these wastewaters is very variable. A great variety of organic chemicals can be determined among the principal components of these types of wastewaters. Antibiotics are the major group of pharmaceuticals. Among all the other pharmaceutical drugs and substances, antibiotics are important compounds due to its serious irreversible increase the release to the environment^{[1][2][3][4][5]}

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MITRA INDUSTRIES (P) LTD. is a reputed and established name in the field of Blood Collection Bags and CAPD bags for home dialysis, Products are of high quality and supplied across Asia Europe and parts of African sub-continent.

About Authors:
Abhilash Kumar, Navneet Upadhay
School of Pharmaceutical Sciences,
Shoolini University,
Solan, H.P., India
*abhilashkumarchawla421@gmail.com

Abstract
The objective of this work is to overview the process validation in various pharmaceutical processes. Quality is the most important requirement in the manufacturing process. All the drugs must be manufactured to the highest quality level. Quality cannot be guaranteed just by end product testing but we have to control carefully each critical step during the manufacturing process. Thus process validation plays an important role to control each critical step in order to maintain quality of the final product. Validation involves a series of activities that are taking place during the life cycle of products and processes. It also involves careful planning of various steps in the process and all the work should be carried out in a structured way according to standardized working procedures.

About Authors:
Ajay Rana
M.Pharm, Shoolini University of Life Sciences,
Solan(H.P.)
*ajayrintu44@gmail.com

Abstract
Medicinal herbs constitute important source of drugs. Treatment of diseases with medicinal herbs is called phytothrepary. The study of chemistry of plant derived drugs is known as phytochemistry. Medicinal herbs have given us a number of important drugs, which are mainstays of treatment in synthetic system of medicine. Ayurveda, Siddha, Homeopathy and Herbalism are completely dependent on plants for formulations. Salicin, a glycoside isolated from Salix alba attracted the researchers in the 19^th century and it provided us with most potent weapon, Acetyl-salicylic acid for killing pain. The article highlights the historical usage and pharmacogonosy of medicinal herbs containing salicin.

About Authors:
Arpit Sharma
School of Pharmaceutical Sciences, Shoolini University
Solan, H.P. India
asarpitsharma1@gmail.com

Abstract
The gastro retentive drug delivery system is a novel approach for the drugs having narrow absorption window in the gastrointestinal tract and has poor absorption. Gastro retentive drug delivery system mainly prolongs the gastric emptying time, thereby targeting site-specific drug release. Several techniques such as floating drug delivery system, low density system, raft system, mucoadhesive system, high density system, super porous hydro gel and magnetic system, have been employed. The physiological problems like short gastric residence time and unpredictable gastric emptying time were overcome with the use of floating dosage forms which provide opportunity for both local and systemic effect. Floating drug delivery system enable prolonged and continuous input of the drug to the upper part of the gastro retentional tract and improve the bioavailability of medication that is characterized by a narrow absorption window. The present review addresses briefly about the floating drug delivery system.

About Authors:
Satinder Kumar
Manav Bharti University,
Solan (H.P)
skcrock87@yahoo.in

Abstract:-
Validation is the most recognized and important parameter of GMPs. This article provide introduction about the process validation of pharmaceutical manufacturing process and its importance according to The U.S. Food and Drug Administration (FDA). This work is to present an introduction and general overview on process validation of pharmaceutical manufacturing process. Quality cannot be ensured by sampling, testing, release of materials and products. Quality assurance techniques must be used to build the quality into the product at every step and not just tested for at the end. Process validation of a process will ensure production of drug of reproducible quality. In pharmaceutical industry, Process Validation performs this task to build the quality into the product because according to ISO 9000:2000, it had proven to be an important tool for quality management of pharmaceuticals.

Stevia rebaudianais a well known medicinal herb contains antibacterial, antifungal, anti-inflammatory, anti-viral, anti-yeast, cardiotonic diuretic and hypoglycaemic properties. This herb has been used in Ayurveda in India since centuries. Stevia is a perennial herb belonging to the family Asteraceae, is one of the most valuable tropical medicinal plant. Leaves of this plant produce zero calorie, high potency sweetener and substitute to sucrose, being about 300 times sweeter than sucrose. The compounds, named stevioside and rebaudiocide give stevia its taste. In India number of diabetic people in the age group of 25-45 is about 15% and is also increasing at an alarming pace. In addition, India is the largest consumer of sugar in the world. So stevia is attaining attention in Indian market as a healthy alternative sweetener to sugar. Stevia has no calcium cyclamate, no saccharim, no aspartame and no calories. It is safe for diabetics, as it does not affect blood sugar levels and have no neurological or renal side effects.

About Authors:
Shalini Sharma, Manoj Prashar
Manav Bharti University,
Solan

ABSTRACT
Stomach specific mucoadhesive drug delivery system(MADDS) is one of the most prominent and latest system which sustain drug blood concentration and controlling the rate of drug delivery to the target tissue. These systems interact with mucin molecule and mucous layer covering the mucosal epithelial surface and prolong the residence time of the dosage form at the site of application or absorption and thus contribute to improve or better therapeutic performance of drug. This review article also present the polymer used for preparation of mucoadhesive tablet, mechanism of mucoadhesion, factor affecting mucoadhesion and recent developments or techniques in formulation of mucoadhesive tablet and invitro and invivo evaluation of mucoadhesive tablets.