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Research News

  • Vera Therapeutics Reports Sustained Kidney Function in Phase 3 Trial of TRUTAKNA for IgA Nephropathy

    Vera Therapeutics has announced final efficacy results from the Phase 3 ORIGIN 3 study of TRUTAKNA™ (atacicept-vymj), reporting sustained stabilization of kidney function and a reduced risk of kidney disease progression in adults with primary IgA nephropathy (IgAN). The final analysis included 428 patients with primary IgAN who were considered at risk of disease progression.

  • Scientists Uncover New Inherited Eye Disorder Where Night-Vision Loss Comes Before Retinal Damage
    Scientists Uncover New Inherited Eye Disorder Where Night-Vision Loss Comes Before Retinal Damage
    An international team of researchers has identified a previously unrecognized inherited retinal disorder linked to a rare variant in the EFEMP1 gene. The newly characterized condition primarily affects the peripheral retina and rod photoreceptors involved in vision under low-light conditions, while central vision can remain relatively preserved for many years.
  • Cigarette Smoke and Vaping May Reprogram Blood-Forming Stem Cells, Study Finds
    Cigarette Smoke and Vaping May Reprogram Blood-Forming Stem Cells, Study Finds

    Cigarette smoke and e-cigarette aerosol may have lasting effects on the body's immune system and blood-forming cells, according to a new study by researchers at the University of California, Irvine. The research found that exposure to cigarette smoke and e-cigarette vapor altered immune responses and affected hematopoiesis, the process through which blood cells are produced. The findings raise concerns about the potential long-term consequences of both conventional smoking and vaping on immune function and the hematopoietic system.

  • VEGFR Inhibitors Show Strong Pancreatic Tumor Control in Metastatic Kidney Cancer Study
    VEGFR Inhibitors Show Strong Pancreatic Tumor Control in Metastatic Kidney Cancer Study

    A new study published in Acta Clinica Belgica has found that vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR-TKIs) can produce substantial tumor shrinkage in patients with metastatic clear-cell renal cell carcinoma (ccRCC) involving the pancreas.

  • Adalimumab Emerges as Most Cost-Efficient Biologic for Hidradenitis Suppurativa, Study Finds
    Adalimumab Emerges as Most Cost-Efficient Biologic for Hidradenitis Suppurativa, Study Finds
    A new economic evaluation published in JAMA Dermatology has found that adalimumab 40 mg administered weekly offers the most consistent balance between treatment effectiveness and cost among currently approved monoclonal antibody therapies for hidradenitis suppurativa (HS).
  • Dry Eye Remains an Overlooked Menopause Symptom, Bausch and Lomb Survey Reveals
    Dry Eye Remains an Overlooked Menopause Symptom, Bausch and Lomb Survey Reveals
    Dry eye is significantly underrecognized as a symptom associated with perimenopause and menopause, according to findings from a new survey conducted by Bausch + Lomb. The survey highlights a substantial awareness gap among women and points to the need for greater attention to eye health during this stage of life.
  • Robot-assisted surgery shows clinical advantages over laparoscopic surgery for gastric cancer
    Robot-assisted surgery shows clinical advantages over laparoscopic surgery for gastric cancer
    Surgery remains the primary curative treatment for gastric cancer, with laparoscopic gastrectomy (LG) established as a standard minimally invasive approach. While LG offers faster recovery than open surgery, it remains technically demanding because surgeons must operate within a confined space using rigid instruments that can amplify hand tremors.
  • A smart cancer drug developed by India, could replace chemotherapy
    A smart cancer drug developed by India, could replace chemotherapy

    New ‘Smart’ Cancer Drug Targets Tumor Cells While Sparing Healthy Tissue. Scientists in India have developed a promising experimental cancer drug designed to activate mainly inside cancer cells, potentially offering a more selective approach than conventional chemotherapy.

  • Beyond Weight Loss: Scientists Uncover How GLP-1 Drugs May Reduce Addictive Cravings
    Beyond Weight Loss: Scientists Uncover How GLP-1 Drugs May Reduce Addictive Cravings

    Drugs such as Ozempic and other GLP-1 receptor agonists, widely known for their effects on diabetes and weight management, may have potential beyond appetite control, with emerging research suggesting they could also help reduce cravings associated with addiction. A recent report published by The Conversation highlights new evidence pointing to a specific brain pathway that may explain how these medicines influence reward-driven behaviours.

  • Breakthrough Study Identifies Circular RNAs as Promising Targets to Reduce Cancer Therapy Side Effects
    Breakthrough Study Identifies Circular RNAs as Promising Targets to Reduce Cancer Therapy Side Effects

    As cancer treatments continue to improve survival rates, managing treatment-related side effects remains one of the biggest challenges in oncology. A new scientific review has highlighted the significant role of circular RNAs (circRNAs) in understanding and potentially reducing the toxic effects associated with chemotherapy, radiotherapy, and immunotherapy.

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