siRNA TECHNOLOGY:AN EMERGING TREND IN THERAPEUTICS
About Authors:
Vaibhav Patel*, Punit Bhatnagar, Gopal Rai, Alok Pal Jain
Guru Ramdas Khalsa Institute of Science & Technology (Pharmacy),
Jabalpur
*vaibhavpatel281@gmail.com
Introduction
Gene therapy by small interfering RNAs (siRNAs) hasbeen emerging as innovative nucleic acid medicines with increasing knowledge on the molecular mechanisms of endogenous RNA interference. Gene silencingis a promising tool for the treatment of numerous human diseases that cannot be cured by rational therapies. The primary success of siRNA applications depends on suitable vectors to deliver therapeutic genes.

The newly carved West Central Railway Zone with its headquarters at Jabalpur comprises of Jabalpur and Bhopal divisions of erstwhile Central Railway and Kota division of erstwhile Western Railway. The formal gazette notification announcing the formation of this new zonal railway was issued on 4th July 2002 by the Ministry of Railway, Govt. of India.

