Uttar Pradesh

Tweet India Pharmaceuticals Pvt. Ltd. is being headed by Mr. A. K. Arora, who is backed up by his more than 35 years practical and successful experiences of Pharmaceutical Industry and has given his precious and valuable guidance in formulating latest strategies which is followed by many Pharmaceutical Companies, and has been the milestone for the Pharmaceutical Industries.

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Ministry of Defence Kanpur Invites Application for 270 Tradesman Mate, pharmacists and Various Posts

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ABOUT AUTHORS
Abdul Waheed*, Swati Pathak, Roohi Mirza
Department of Pharmacology,
Amity Institute of Pharmacy,
Amity University, Noida, U.P., India
*abdul.waheed2050@gmail.com

ABSTRACT
Epilepsy is a chronic brain disorder characterized by tendency to recurrent seizures or fits. The seizures can leads to loss of consciousness, disturbance of movement, muscle spasms, autonomic and mental functions. Epilepsy is developed because of imbalance in nerve signalling chemical called neurotransmitters. During epilepsy, the level of excitatory neurotransmitter glutamate increases and the level of inhibitory neurotransmitter GABA decrease. These lead to abnormal signalling in brain causes epilepsy. Primary diagnosis of epilepsy includes eye–witness and family history. Electroencephalograph (EEG) is the cornerstone for diagnosis of epilepsy and measures the brain wave activity. Neuroimaging like computed tomography (CT) scan, magnetic resonance imaging (MRI) and positron emission tomography (PET) techniques are used to diagnose abnormalities in structure and function of brain. Video recording is also useful for the monitoring of epileptic events. The most common approach of treatment is to prescribe antiepileptic drugs (AEDs). Three generations of AEDs including phenytoin, valproate, carbamazapine, lamotrigine, Oxcarbazepine, Primidone,Phenobarbitone,Gabapentin, Topiramate, Levetiracetam, Felbamate, Rufinamide, Zonisamide, Tiagabinand Vigabatrin etc. are prescribed. These AEDs have some teratogenic effects on  pragnent woman and lactating mother; need precautions. Instead of  pharmacological approaches, Non-pharmacological approaches also used for the treatment of epileptic seizures like ketogenic diet, atkins diet, yoga etc. Thr purpose of this review is to update the current knowledge on epilepsy classification, diagnostics, approaches of treatment, pathophysiology, mechanism of epileptogenesis and teratogenic effects.

The UP Rural Institute of Medical Sciences & Research is a premier autonomous institute established by Govt. of U.P. under Act 2005. The institute is running full-fledged medical college and fully equipped Multi Specialty 700 bedded hospital.

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National Investigation Agency (NIA) invites application from reputed individuals/ firms/ agencies for competent Scientific consultants for engagement/ empanelment as Scientific resource persons or consultants who are keen to work in agency on short term contract basis against the following posts initially for a period of 01 year which can be extended further as per mutual consent. They will be engaged on need basis and periodicity of engagement may vary depending upon case to case basis. They will not be entitled to any other allowance like House Rent Allowance, Medical reimbursement, Leave Travel Concession etc. However, they will be entitled to TA/DA as payable to their counterparts in the regular cadre of the NIA or as per the decision of competent authority in NIA. The person so engaged shall not have may right to claim regularisation/ absorption in the organisation after the expiry of period of contract. The total vacancies of Scientific consultants location and rank-wise are as under:

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