Delhi University

Opportunity for pharmacy professionals in COPD research at VPCI

The Vallabhbhai Patel Chest Institute (VPCI) is a unique postgraduate medical institution devoted to research, teaching and patient care in the field of chest diseases. It is a University of Delhi maintained institution and is funded entirely by the Ministry of Health and Family Welfare, Government of India. The Institute is ideally located in the heart of the main campus of the University of Delhi, providing the requisite academic environment. The Institute fulfills the national need for providing relief to large number of patients in the community suffering from Chest Diseases. It has eminently discharged its role and has earned a unique place in the field of Chest Medicine.

Post : Senior Research Fellow

Walk-in at Vallabhbhai Patel Chest Institute, University of Delhi as Research Associate

The Vallabhbhai Patel Chest Institute (VPCI) is a unique postgraduate medical institution devoted to the study of chest diseases. It is a University of Delhi maintained institution and is funded entirely by the Ministry of Health and Family Welfare, Government of India. The institute is ideally located in the heart of the main campus of the University of Delhi, providing the requisite academic environment.

FORMULATION, DEVELOPMENT AND EVALUATION OF ANTI-IMPLANTATION ACTIVITY OF INTRAUTERINE SYSTEM OF CENTCHROMAN (SAHELI) USING WISTAR ALBINO RATS

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ABOUT AUTHORS:
Himani Devliyal*, S.S Agarwal
Department of Pharmacology,
Delhi Institute of Pharmaceutical Sciences and Research, Delhi University, New Delhi
himanidevliyal@gmail.com

ABSTRACT
Centchroman – A Non-steroidal, post-coital anti-implantation drug which is generally popular as SAHELI is one of the best agents available. The fundamental aim of this study  was to formulate such an Intra-uterine System of Centchroman which should be safe and acceptable. This new drug delivery system surpasses the first pass metabolism, thus increasing the bioavailability and reducing the drug load. This formulation delivered the drug upto 21 days. Polylactic-co-glycolic acid served as the best fit polymer for delivering the drug. The best optimized formulation was selected and subjected to stability studies.  The effect of the foreign bodies was also observed on the fertility, mating behaviour and estrous cycle of the rats along with anti-implantation activity of the IUS. This formulation was tested on Wistar albino rats and is proved to be safe at the optimized dose level. The formulation exhibited pre-implantation loss of 100% and post-implantation loss of 0% in Wistar albino rats at a particular dose when delivered on 1st day and 4th day post-coital. Experimental part on animals showed that any foreign body, if put inside the uterus would not affect the fertility unless the size is more than 6mm. Results showed that 3mm objects had no effect on fertility. The foreign bodies and the IUS showed neither any alteration in the estrous cycle nor on the mating behavior of the animals.

Vacancies for the positions of JRF/ SRF at University of Delhi

Eligible candidates are requested to send a copy of resume along with the attested copies of the certificates/testimonials by 31st December at the address given below for the temporary position of JRF/ SRF for the period of one year, extended till the operation of project, under DST sponsored project of Dr. Vibha Tandon (PI) entitled

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