• PharmaTutor
    10 August 2012

    PHARMACODYNAMIC INFLUENCE OF VITAMIN E AND ESOMEPRAZOLE ON GASTRO PROTECTION IN PYLORUS LIGATION INDUCED ULCERS IN RATS

    About Authors:
    NITIN M, MOHAN REDDY U*
    Department of Pharmacology,
    H.K.E.S’s, Matoshree Taradevi Rampure Institute of Pharmaceutical Sciences,
    Sedam Road, Gulbarga- 585 105, Karnataka
    *mohanreddy.udumula@gmail.com

    ABSTRACT
    Gastric ulcer is one of the most prevalent gastrointestinal disorders, which affects approximately    5-10% of people during their life. The present study was aimed to find out the pharmacodynamic influence of vitamin E and esomeprazole and their combination on gastro intestinal parameters in pylorus ligation induced ulcers in rats in single and multiple dose studies.  Various parameters were studied in  pylorus ligation induced ulcer model viz. gastric volume, pH, total acidity, free acidity, and ulcer index.The antiulcer effect of the combination of vitamin E 0.9 mg/200 g and esomeprazole 0.54 mg/200 g b.w orally was compared with the reference standard esomeprazole 0.54 mg/200 g b.w orally. The ulcer index was calculated and other biochemical parameters of gastric juice were estimated. The ulcer index of combination showed significant (P < 0.05) reduction while other biochemical parameters like volume, pH, free acidity and total acidity of gastric juice showed highly significant (P < 0.001) reduction when compared to control and standard esomeprazole.

  • 6 August 2012
    Filling up of posts of Technical/ Scientific services of Food Safety and Standards Authority of India - 32 posts

    The Food Safety and Standards Authority of India (FSSAI) is an autonomous statutory Authority set up under the Food Safety and Standards Act, 2006 for laying down science based standards for articles of food and to regulate their manufacture, storage, distribution, sale and import to ensure availability of safe and wholesome food for human consumption.

  • 31 July 2012
    Biocon opens for post of Junior Executive in Production - Freshers can apply

    Biocon is a research-driven, global healthcare company with a strong matrix of capabilities along the biopharmaceutical value chain. Focusing on unmet medical needs in cancer, diabetes and inflammatory diseases, it offers novel therapies on a platform of affordable innovation.

  • 31 July 2012
    EVALUATION OF ANTI-STRESS (ADAPTOGENIC) ACTIVITY OF LUFFA CYLINDRCIA FRUIT EXTRACT

    About Authors:
    Sachin Kaushik*, Dr. shivakumar Hugar
    P.G. Department of Pharmacology,
    B.L.D.E.A.’s college of Pharmacy,
    Bijapur- 586103,
    Karnataka,India
    *sachin_2004_kaushik@yahoo.com

    ABSTRACT:
    In the present study antistress activity was assessed against anoxia tolerance, swimming endurance and cold restraint stress models. In anoxia tolerance test, the mean time of appearing first convulsion in mice was taken as end point to determine the time of anoxia.  In swimming endurance test the mean time of swimming performance was recorded.The end point taken was when the animals remained at the bottom of swimming tank for 10 sec. Biochemical estimation like glucose, cholesterol, triglycerides and BUN and weight of organs were measured in cold restraint stress model.

  • 30 July 2012
    Job as Assistant General Manager - Production in Biocon

    Biocon is a research-driven, global healthcare company with a strong matrix of capabilities along the biopharmaceutical value chain. Focusing on unmet medical needs in cancer, diabetes and inflammatory diseases, it offers novel therapies on a platform of affordable innovation.

  • 23 July 2012
    Career as Marketing - Preclinical research in Natural Remedies

    Natural Remedies, a pioneer in phytopharmaceuticals is today credited with integrating scientific approach to search medicines and health supplements ensuring purity, safety and affordability.

  • 16 July 2012
    Multiple Vacancies in OMEGA HEALTHCARE as Trainee Coders - Freshers

    Omega Healthcare has extensive experience in providing services in a variety of hospital-based and office-based physician specialties.  We also have experience in providing services to A/R Management companies and their hospital clients for their credit balance account, regular accounts receivable and facility coding needs.  Our delivery organization is driven by quality and Six Sigma methodologies, which ensure improved processes and client satisfaction.

  • 15 July 2012
    REGIONAL MEDICAL RESEARCH CENTRE opens for Scientist C

    Applications are invited upto 28th July 2012 for one post of Scientist ‘C’ (Organic Chemistry / Natural Product Chemistry) in the Pay Band PB-3 Rs.15600-39100 + Grade Pay Rs. 6600/- at the ICMR's Regional Medical Research Centre, Belgaum.

    Post: Scientist C

    [adsense:336x280:8701650588]

  • 14 July 2012
    Opportunity for M.Sc / B.Pharm / M.Pharm to work as Executive – QA & QC in Himalaya

    The Himalaya Drug Company was founded in 1930 by Mr. M. Manal with a clear vision to bring Ayurveda to society in a contemporary form and to unravel the mystery behind the 5,000 year old system of medicine. This included referring to ancient ayurvedic texts, selecting indigenous herbs and subjecting the formulations to modern pharmacological, toxicological and safety tests to create new drugs and therapies.

  • 13 July 2012
    Require Product executive / Medical representative in Finition Solutions - 10 posts

    Finition Solutions is involved in businesses as diverse as HR Services, Information Technology, Manufacturing and Bio (Environmental Solutions).
    • HR Services
    • Information Technology
    • Environmental Solutions

    Post: product executive/medical representative

    [adsense:336x280:8701650588]

Subscribe to Karnataka