Karnataka

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Post : Product Engineering Software Architect - Medical System

Vacancy at Raichur, Karnataka at pharma industry (API plant)

Reputed Pharma Company from Karnataka

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ABOUT AUTHORS
Balasubramanian Sathyamurthy*, Sushmitha.H.S
Department of Biochemistry,
Ramaiah College of Arts, Science and Commerce,
Bangalore, Karnataka, India

ABSTRACT:
The key proteins involved in causing dengue are seven major proteins, which are considered as major therapeutic targets for dengue drug development. Recent studies have reported positively for NS1 protein in dysregulation of causing dengue process in humans. Dragon fruit seed phytochemicals are reported to have antioxidant and antiviral properties. In the present study we studied binding efficiency of 11 compounds that are present in the dragon fruit seeds with NS1 Protein through Insilico methods. By our virtual screening and docking result, we found that the Compound A, Compound B and Compound C have highest binding affinity with the NS1 Protein and also we predicted the binding site amino acid residues and the nature of hydrogen bonding. However more invivo experimental validation of our results with animal models will enlighten the development of more potent drugs from these compounds for treatment of dengue.

Acharya & BM Reddy College of Pharmacy, affiliated to Rajiv Gandhi University of Health Sciences (RGUHS), Karnataka, Bengaluru, approved by Pharmacy Council of India (PCI) and All India Council for Technical Education (AICTE). Accredited by National Board of Accreditation (NBA) and Life Sciences Sector Skill Development Council (LSSSDC), New Delhi. The college is Re-accredited by National Assessment and Accreditation Council (NAAC) with CGPA 3.26 on 4.00. It is Recognized as Scientific and Industrial Research Organization (SIRO) by DSIR, Ministry of Science & Technology, Govt. of India and is Recognized by Government of Karnataka and University Grants Commission (UGC). Received the Best Industry Linked Pharmacy Institute in India award by AICTE-CII Survey-2016.

Post : Junior Research Fellow

Covance is one of the world’s largest and most comprehensive drug development services companies with more than 11,000 employees in 60 countries. Through its nonclinical, clinical and commercialization services, Covance has helped pharmaceutical and biotech companies develop one-third of all prescription medicines in the market today.

Post : Assistant Manager, Safety Sciences

B.E.A. School of Pharmacy was merged into Bapuji Pharmacy College. The college had envisioned as premier institute of Pharmacy Education and preparing students with orientation for National and International needs. As a part of development, an independent college building with 21st Century infrastructure has been developed. The institutions are committed for excellence in Pharmacy Education with the culmination of team work by the experienced teaching staff with good educational practices. The institutions are committed also to the philosophy of Learn How to Learn.

Post : Teaching job

Research at inStem addresses the genetic mechanisms of potency, differentiation and proliferation in human pluripotent cells, examines clinical manifestations of diseases that can potentially be treated by stem cells, models human diseases using stem cells, uses model organisms such as Planaria and Hydra to address fundamental questions in regenerative biology, develops platforms to interrogate signaling pathways with new chemical entities, and finally, develops tools that will help to better understand the biology driving stem cells and eventually treat disease states.At inStem, research is primarily carried out by groups who work on tightly-knit themes, crossing boundaries and developing new approaches to address questions larger than the expertise of individual researchers.

Post : Research Assistant

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